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Photo of Dr. Howard Mark Lederman, M.D., Ph.D.

Howard Mark Lederman, M.D., Ph.D.

Director, Immunodeficiency Clinic
Professor of Pediatrics


Appointment Phone


Main Location

The Johns Hopkins Hospital

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »


  • Director, Immunodeficiency Clinic
  • Director, Ataxia-Telangiectasia Clinical Center
  • Director, Pediatric Immunology Laboratory
  • Professor of Pediatrics
  • Joint Appointment in Medicine

Centers & Institutes


  • Medicine - Infectious Diseases
  • Pathology
  • Pediatrics - Allergy and Immunology


The Johns Hopkins Hospital

Appointment Phone: 410-955-5883

600 N. Wolfe Street
Sheikh Zayed Tower Suite 1102
Baltimore, MD 21287 map
Phone: 410-955-5883
Fax: 410-955-0229


Allergy and Immunology, Antibody Deficiency, Ataxia-Telangiectasia, Chronic Granulomatous Disease, Common Variable Immunodeficiency, Complement Deficiency, DiGeorge Syndrome, Gamma Globulin Therapy, Hyper-IgE Syndrome, Hyper-IgM Syndrome, Hypogammaglobulinemia, IgA Deficiency, IgM Deficiency, Leukocyte Adhesion Deficiency, Primary Immunodeficiency Diseases, Severe Combined Immunodeficiency, Wiskott-Aldrich Syndrome, X-linked Agammaglobulinemia

Research Interests

Primary Immunodeficiency Diseases; Ataxia-Telangiectasia; IgA deficiency; Common variable immunodeficiency; Chronic granulomatous disease and other disorders of phagocytes; Severe combined immunodeficiency; Hypogammaglobulinemia; Immunoglobulin therapy; IVIG; DiGeorge syndrome; Wiskott-Aldrich syndrome; Hyper-IgM syndrome; Hyper-IgE syndrome; Complement deficiency; X-linked agammaglobulinemia; Antibody deficiency; IgM deficiency

    Additional Information

  • Education +


    • University of Michigan Medical School / MD (1977)


    • Johns Hopkins University School of Medicine / Pediatrics (1981)


    • Hospital for Sick Children / Immunology (1983)


    • American Board of Pediatrics / Pediatrics (1984)
  • Research & Publications +

    Clinical Trial Keywords: Immunoglobulin, Gamma globulin, Ataxia- Telangiectasia

  • Academic Affiliations & Courses +
  • Activities & Honors +


    • American Association of Immunologists 
    • American Society for Microbiology 
    • Clinical Immunology Society 
    • Infectious Diseases Society of America
    • Society for Pediatric Research 
  • Videos & Media +
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