Simon Best, MD

Assistant Professor, Otolaryngology-Head and Neck Surgery

OFFICE PHONE
410-955-1654

EDUCATION – Medical School
Yale University School of Medicine

EDUCATION – Residency
Johns Hopkins Hospital

EDUCATION – Fellowship
Massachusetts General Hospital, Center for Laryngeal Surgery and Voice Rehabilitation

CLINICAL INTERESTS

• Recurrent Respiratory Papillomatosis (RRP)
• Laryngeal cancer and precancerous vocal cord dysplasia
• Care of the performing and professional voice
• Vocal cord paralysis
• Laryngeal and Tracheal stenosis

RESEARCH INTERESTS

• Immunobiology of Recurrent Respiratory Papillomatosis (RRP)
• Development of novel therapeutic treatments for Recurrent Respiratory Papillomatosis (RRP)
• Voice and swallowing outcomes following skull base surgery

BOARD CERTIFICATION
American Board of Otolaryngology

PRINCIPAL HOSPITALS
The Johns Hopkins Hospital
Greater Baltimore Medical Center (GBMC)

PUBLICATIONS

Best SR, Friedman AD, Landau-Zemer T, Barbu AM, Burns JA, Freeman MW, Halvorsen YD, Hillman RE, Zeitels SM. The safety of bevacizumab (Avastin) for the treatment of Recurrent Respiratory Papillomatosis.  In press.

Best SR, Starmer HM, Agrawal Y, Chien WW, Hillel AT, Francis HW, Tamargo RJ, Akst LM. Risk factors for vagal palsy following cerebellopontine angle surgery. Otolaryngol Head Neck Surg. 2012 Mar 23.

Starmer HM, Best SR, Agrawal Y, Chien WW, Hillel AT, Francis HW, Tamargo RJ, Akst LM. Prevalence, characteristics, and management of swallowing disorders following cerebellopontine angle surgery. Otolaryngol Head Neck Surg. 2011 Nov 18.

Best SR, Ha PK, Blanco RG, Saunders JR Jr, Zinreich ES, Levine MA, Pai SI, Walker M, Trachta J, Ulmer K, Murakami P, Thompson R, Califano JA, Messing BP.  Factors associated with pharyngoesophageal stricture in patients treated with concurrent chemotherapy and radiation therapy for oropharyngeal squamous cell carcinoma.  Head Neck. 2011 Dec;33(12):1727-34.

Best SR, Fakhry C. The prevalence, diagnosis, and management of voice disorders in a National Ambulatory Medical Care Survey (NAMCS) cohort. Laryngoscope. 2011 Jan;121(1):150-7.

Peng S, Best SR, Hung CF, Loyo M, Lyford-Pike S, Flint PW, Tunkel DE, Saunders JR, Wu TC, Pai SI. Characterization of human papillomavirus type 11-specific immune responses in a preclinical model. Laryngoscope. 2010 Mar;120(3):504-10.

Best SR, Peng S, Juang CM, Hung CF, Hannaman D, Saunders JR, Wu TC, Pai SI. Administration of HPV DNA vaccine via electroporation elicits the strongest CD8+ T cell immune responses compared to intramuscular injection and intradermal gene gun delivery. Vaccine 2009 Sep 4;27(40):5450-9.