Current News Releases
Current News Releases
Findings highlight dynamic nature of disease and need for ongoing risk assessment
A Johns Hopkins-led study of outcomes among 1,200 people with implanted defibrillators — devices intended to prevent sudden cardiac death from abnormal heart rhythms — shows that within a few years of implantation, one in four experienced improvements in heart function substantial enough to put them over the clinical threshold that qualified them to get a defibrillator in the first place.
Named the #1 hospital in Maryland and the only Maryland hospital to be nationally ranked in 15 medical specialties in the Best Hospitals 2015-16 list
The Johns Hopkins Hospital ranked in the top five in nine specialties and #3 overall in the nation in the U.S. News & World Report annual Best Hospitals list, sharing the spot with UCLA Medical Center, in this year’s ranking of 4,716 hospitals. In the magazine’s ranking of hospitals in the state, The Johns Hopkins Hospital was again ranked #1 in all specialties. It also ranked #1 in all specialties in Baltimore.
Johns Hopkins study reveals potential of cellphone interventions among diverse inner city pregnant and postpartum women
In a survey of a diverse group of almost 250 young, low-income, inner-city pregnant and postpartum women, Johns Hopkins researchers have learned that more than 90 percent use smartphones or regular cellphones to give and get information.
New method moves promising strategy closer to clinical use
Experiments show neurons firing as rats plan their next move
By using electrode implants to track nerve cells firing in the brains of rats as they plan where to go next, Johns Hopkins scientists say they have learned that the mammalian brain likely reconstructs memories in a way more like jumping across stepping stones than walking across a bridge. A summary of their experiments, published in the journal Science on July 10, sheds light on what memories are and how they form, and gives clues about how the system can fail.
“Pairing” model designed to address Baltimore’s “food deserts”
Buying fresh fruits and vegetables can be hard for families living in low-income urban neighborhoods, many of which are known as “food deserts” for their lack of full-service grocery stores that stock healthy food.
Borrowing a page from a winning team’s playbook, Johns Hopkins endocrinologist Nestoras Mathioudakis, M.D., and his colleagues are taking on the topic of managing hospital patients’ diabetes.
New nerve cell connections on sensory cells in mice could be at fault
Conventional wisdom has long blamed age-related hearing loss almost entirely on the death of sensory hair cells in the inner ear, but research from neuroscientists at Johns Hopkins has provided new information about the workings of nerve cells that suggests otherwise.
In a genome-sequencing study of pancreatic cancers and blood in 101 patients, Johns Hopkins Kimmel Cancer Center scientists say they found at least one-third of the patients’ tumors have genetic mutations that may someday help guide precision therapy of their disease. Results of blood tests to detect DNA shed from tumors, they say, also predicted cancer recurrence more than half a year earlier than standard imaging methods.
In a review of nearly 2,000 surveys with people whose loved ones died of cancer, researchers led by Johns Hopkins experts say they found a 40 percent increase over a 12-year period in the number of patients with cancer who participated in one form of advance care planning — designating durable power of attorney privileges to a loved one — but no corresponding impact on their rates of aggressive medical care received in the last weeks of life.
Study reveals likely differences in processing among individuals, areas of the body
Research with human tissue and cells suggests that genetic variations, in addition to failure to comply with treatment regimens, may account for some failures of an anti-HIV drug to treat and prevent HIV infection.
Johns Hopkins Medicine study challenges current standard recommendations
A new study led by Johns Hopkins Medicine researchers of patients hospitalized with anorexia nervosa shows that a faster weight gain during inpatient treatment — well beyond what national standards recommend — is safe and effective.
Johns Hopkins researchers have found that offspring born to mother rats stressed during pregnancy lost weight faster and failed to turn on appropriate brain hunger signals in response to exercise and food restriction, compared to offspring from non-stressed mothers. The research reveals a specific combination of stress, personality, and environmental factors that may contribute to anorexic behaviors.
The Johns Hopkins Armstrong Institute for Patient Safety and Quality and The Queen’s Health Systems in Honolulu have entered into a collaboration agreement to improve patient safety and quality of care initiatives at hospitals in the state of Hawaii.
The Johns Hopkins Drug Discovery (JHDD) program, created with the mission of identifying novel drug targets arising from Johns Hopkins faculty research and translating them into new therapeutics, and the Institute of Organic Chemistry and Biochemistry , The Czech Academy of Sciences (IOCB Prague) have entered into a five-year drug discovery research agreement to develop small-molecule and peptide drugs for a range of therapeutic areas including neurological diseases, cancer, and gastrointestinal disorders.
New protein found to help cells move from behind
When Greek mythology and cell biology meet, you get the protein Callipygian, recently discovered and named by researchers at The Johns Hopkins University for its role in determining which area of a cell becomes the back as it begins to move.
Basic research seriously challenges a long-standing hope that blocking calcium from entering energy-making mitochondria inside heart cells could prevent heart attack damage
Researchers have long had reason to hope that blocking the flow of calcium into the mitochondria of heart and brain cells could be one way to prevent damage caused by heart attacks and strokes. But in a study of mice engineered to lack a key calcium channel in their heart cells, Johns Hopkins scientists appear to have cast a shadow of doubt on that theory. A report on their study is published online this week in Proceedings of the National Academy of Sciences.
Machinery helps guide chromosomes during division
For cell division to be successful, pairs of chromosomes have to line up just right before being swept into their new cells, like the opening of a theater curtain. They accomplish this feat in part thanks to structures called centrioles that provide an anchor for the curtain’s ropes. Researchers at Johns Hopkins recently learned that most cells will not divide without centrioles, and they found out why: A protein called p53, already known to prevent cell division for other reasons, also monitors centriole numbers to prevent potentially disastrous cell divisions.
New research from The Johns Hopkins University suggests that a molecule commonly found “decorating” brain cells in higher animals, including humans, may affect brain structure. The study showed that small changes made in how sialic acid attaches to cell surfaces can cause damaged brain structure, poor motor skills, hyperactivity and learning difficulties in mice. The findings suggest that sialic acid plays a significant role in how brain cells communicate, possibly shedding light on the underlying causes of certain brain disorders.
The drug approved to treat patients infected with the hepatitis C virus needs no help from other antivirals, according to a study released online this week in the journal Hepatology.