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Open Clinical Research Studies

Studies are currently being conducted locally in the following specialty areas, with more specialty studies planned in the future.

Cardiovascular Studies

Contact: 443-546-1400

A multi-center, randomized, double-blind, active-controlled, parallel- group Phase 3 study to evaluate the efficacy and safety of LCZ696 compared to ramipril on morbidity and mortality in high risk patients following an acute myocardial infarction (LCZ696G2301)
Principal Investigator:  William R. Herzog, MD
Contact: 443-546-1400
A 52 week, open label evaluation of the effects of sacubitril/valsartan (LCZ696) therapy on biomarkers, myocardial remodeling and patient-reported outcomes in heart failure with reduced left ventricular ejection fraction (PROVE-HF)
Principal Investigator:  Keith Friedman, MD
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Effect of Dalcetrapib vs Placebo on CV Risk in a Genetically Defined Population With a Recent ACS (dal-GenE)
Principal Investigator: William R. Herzog, M.D.
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A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure (COMMANDER HF)
Principal Investigator: William R. Herzog, M.D.
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Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation  Acute Coronary Syndrome (UPSTREAM):  An ED_Based Clinical Registry.
Principal Investigator: William R. Herzog, M.D.
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Gastroenterology Studies

The Cancer of the Pancreas Screening-5 CAPS Study
Principal Investigator: Michael Goggins, M.D. / Mimi Canto, M.D.
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Multi-center Clinical Study to Evaluate the Coldplay Focal Ablation System for the Treatment of Patients With Previously Untreated Dysplastic Barrett's Epithelium
Principal Investigator: Mimi Canto, M.D.
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Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus
Principal Investigator: Mimi Canto, M.D.
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COLDPLAY 3: MULTI-CENTER CLINICAL STUDY TO EVALUATE THE COLDPLAY CRYOBALLOON FOCAL ABLATION SYSTEM FOR THE TREATMENT OF PATIENTS WITH PREVIOUSLY UNTREATED DYSPLASTIC BARRETT’S EPITHELIUM
Principal Investigator: Mimi Canto, M.D.
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Orthopedic Surgery

Contact: 443-546-1555

Liposomal Bupivacaine vs. Interscalene Nerve Block for Pain Control After Total Shoulder Arthroplasty: A Randomized Clinical Trial
Principal Investigator: Uma Srikumaran, M.D.
Contact: 443-546-1555
A prospective, single blinded, multi-center, randomized, controlled, pivotal study to assess the safety and effectiveness of the InSpace™ device for treatment of full thickness Massive Rotator Cuff Tears.
Principal Investigator: Uma Srikumaran, M.D.
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Arthroscopic Transosseous vs. Anchored Rotator Cuff Repair: A Randomized Clinical Trial
Principal Investigator: Uma Srikumaran, M.D.
Contact: 443-546-1555
Pyrocarbon IDE Study
Principal Investigator: Uma Srikumaran, M.D.
Contact: 443-546-1555