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Keratoconus Research

Corneal cross linking diagram

The causes of keratoconus and underlying pathogenic changes are poorly understood. The keratoconus research team, comprised of some of the most accomplished experts in research and clinical care, are trying to change that. Basic science discoveries are being translated into increased understanding of the origins and progression of the disease, and exploration of new treatments and therapies.

Areas of Focus

Our keratoconus researchers are currently focused on:

  • Establishing a keratoconus patient database with clinical information including disease severity, associated medical problems, and family history
  • Identifying novel therapies for keratoconus through the study of biological pathways that govern the outermost layer of the cornea (epithelium)
  • Investigating the importance of mild, chronic inflammation as a cause of keratoconus
  • Identifying genes and testing DNA associated with keratoconus using new methods of genetic analysis
  • Developing and testing new treatments for keratoconus
  • Developing cell culture models of keratoconus to specifically study candidate gene functions

Read more about our current research.

Our Faculty

James Foster

James Foster, Ph.D.

Research Associate
Michelle Hessen

Michelle Hessen, O.D.,

Assistant Professor of Ophthalmology
Uri Soinerman

Uri Soiberman, M.D.

Assistant Professor of Ophthalmology
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