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Current Research in Cornea, Cataract and External Disease

The research faculty of the Cornea, Cataract and External Disease Division at the Johns Hopkins Wilmer Eye Institute are engaged in research aimed at improving how corneal disease is diagnosed, treated and managed.

Research in Action

Dr. Soiberman and CXL procedure

Innovative New Treatments

Wilmer now offers corneal collagen cross-linking, a minimally-invasive, advanced therapy that slows or stops the progression of keratoconus.

Drs. Schein and Merali

Quality and Safety Research

Dr. Farhan Merali researches the science of quality and safety in eye care.


Areas of Research

Contact Lenses

  • Dr. Divya Srikumaran is researching the burden of contact lenses fittings for patients with keratoconus and similar ocular diseases.

Corneal Collagen Cross-linking

Corneal Transplantation

  • Dr. Albert Jun is researching cell-based approaches for corneal transplantation.
  • Dr. Christina Prescott is engaged in research relating to pediatric corneal surgery, to determine which surgical modifications and post-operative management strategies are most successful in pediatric corneal transplantation.

Ebola Eye Disease

  • Dr. Allen Eghrari is co-leading the PREVAIL III eye substudy, the largest Ebola eye study.
PREVAIL study in West Africa

A Medical Science Mission for Eye Care in Ebola Survivors

Among the less-discussed impacts of defeating Ebola: a host of lingering health effects, including long-term vision problems. Allen Eghrari, M.D., leads a field study in West Africa to catalog and characterize the eye complications of Ebola. Read More.

Dry Eye and Sjogren's Syndrome

  • Dr. Esen Akpek is exploring the association of dry eye disease and Sjögren’s syndrome.

Fuchs Dystrophy 

  • Dr. Albert Jun is exploring the cellular causes and non-surgical treatments for Fuchs Corneal Dystrophy.
  • Dr. Allen Eghrari is researching the epidemiology of Fuchs Dystrophy and novel approaches to its treatment.

Global Eyebanking

Keratoconus

topography of the eye

Exploring the Cellular and Genetic Causes of Keratoconus

The causes of keratoconus? and underlying pathogenic changes are poorly understood. The keratoconus research team, comprised of some of the most accomplished experts in research and clinical care, are trying to change that. Learn More.

Lasers in Eye Surgery

  • Dr. Yassine Daoud is exploring outcomes and additional uses of lasers in ocular surgery.

Surgical Education

  • Dr. Shameema Sikder is exploring the use of technology to improve surgical education, beginning with applications in cataract surgery and partial-thickness cornea transplant procedures (DMEK).

Tissue Engineering

  • Dr. Oliver Schein is developing cornea replacement tissue and related ocular materials through materials science and engineering approaches, such as leveraging stem cells, biomaterials and tissue-derived scaffolds to regenerate corneal endothelium. 

Technology in Ophthalmology

  • Dr. Allen Eghrari is focusing on mobile technology and ophthalmology (development of portable eye exams and validation of these mobile resources).