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January 2019
FUNDING OPPORTUNITIES- Back

Johns Hopkins University | Emerson Collective Cancer Research Fund Request for Proposals

The Emerson Collective is proud to announce another round of funding for cancer research at Johns Hopkins University. Johns Hopkins University | Emerson Collective Cancer Research Fund is requesting individual or team proposals for research projects related, but not limited to, immunotherapy, metabolic therapies, early detection advancements, 'high risk/high reward' initiatives and/or -omic approaches cancer and drug development. Positive criteria include the potential of a project to significantly impact our understanding of and/or approaches to the prevention, diagnosis, or treatment of cancer.

Eligibility Criteria
This RFP is open to all faculty undertaking research relevant to cancer at Johns Hopkins. A team of Johns Hopkins | Emerson Collective Cancer Research Fund employees and associates will evaluate the applicant pool.

Applicants will be evaluated on the following positive criteria:

  • The audacity and innovation of the research proposal. Incremental research will not be funded.
  • The potential of the proposed research to affect multiple cancer types
  • The potential to translate said research into further experiments, and clinical trials
  • The applicant's lack of resources to pursue the proposed research
  • Compliance with a two-year maximum timeframe for research The applicant's prior experimental track record will not be the principal determining factor in evaluation.

Timeline

  • RFP Launch: Monday, January 7, 2019
  • Proposals Due: Monday, March 11, 2019 5 p.m. EST.
  • Award Decisions: Monday, May 6, 2019
  • Funding Available: Monday, June 3, 2019
  • One-Year Progress Report Due: Monday, May 4, 2020 " Final Report Due: Monday, May 3, 2021

Amount of Funding
Gift awards range from $50,000 up to $200,000 for up to 2 years for both direct and indirect costs. It may be possible to apply for renewal with additional funding on subsequent RFP rounds. However, new projects will be prioritized. This fund does not support incremental research.

Proposal Submission Guidelines
Applications must be submitted by Monday, March 11, 2019 at 5 p.m EST via the Emerson Collective online submission portal. PLEASE NOTE: The Johns Hopkins institution code (required for application) is EC7.

Research Proposal Guidelines (up to 4 pages)
A recommended outline includes:

  • Title Page (one page): Project title; PI name, title, department, address, phone, and email address; Co-PI(s) name, title, department, address, phone, and email address
  • Lay abstract/Proposal Overview (½ page)
  • Background, Significance and Innovation (½ page)
  • Specific Aims (one page)
  • Scientific Approach and Methods (2 pages): Should include an aim overview, preliminary studies, experimental plan, anticipated results and potential shortcomings. Research proposals must be single-spaced, with margins of no less than ½ inch and in Arial or Helvetica font, size 11 or larger.

Other Documents Guidelines
Milestones, References, Illustrations, Biosketch and budget forms.

  • References (up to 1 page; REQUIRED)
  • Illustrations (no page recommendation; OPTIONAL)
  • Milestones/Deliverables (½ page; REQUIRED)
  • All PI and Co-PI(s) must include an NIH style biosketch describing their educational background, positions held, and key publications (up to 4 pages per investigator).
  • Budget form must also be submitted for each year of funding requested; see template here.
    • Funding is available to support personnel, supplies, equipment, and other general costs associated with the project. Provide a categorical budget outline for the project, see budget template for details. A 15% indirect charge applies to the project costs and should be included in your budget request. Total budget request including the both direct and indirect costs should not exceed $200K.
      o All proposed budgeting must conform to the general policies of the institution.

Acceptance or Rejection
This RFP is not an offer to contract. Due to the high volume of applications, reviewers will be unable to provide feedback on proposals that are not selected. Acceptance of a proposal neither commits Emerson Collective to award a contract to any supplier nor limits Emerson Collective's rights to 1) accept or reject any proposals part or in whole; 2) request further clarification on any specific response, omission or claim made in a response to the RFP; 3) to further evaluate one or more proposals via additional interviews/presentations, or other additional criteria; and 4) to further negotiate the terms submitted in a proposal, including price, prior to the final award.

Questions? Please submit questions to Andrew Isaac in the Office of Foundation Relations (aisaac1@jhu.edu; 410-516-2319).

Ready to submit? Please submit proposals using the Emerson Collective's online submission portal - (LINK TO BE PROVIDED AFTER JANUARY 7TH).


Michael J. Fox Foundation (MJFF) Challenge

No application deadline

The Michael J. Fox Foundation is sponsoring a $2 million prize to the first team to develop a viable selective alpha-synuclein PET tracer and agree to make that tracer available broadly.

The ability to image alpha-synuclein deposition in the brain would be a game-changing achievement for the Parkinson's disease (PD) field. The accumulation of aggregated alpha-synuclein is a pathological hallmark of PD and a priority target for drug development given its hypothesized contribution to neurodegeneration. In vivo imaging of alpha-synuclein pathology could be useful as a biomarker of the presence of disease and disease progression and as a pharmacodynamic tool for drug development. With this prize, the Foundation seeks to attract research teams and accelerate momentum to speed the development of such a tracer.

Contestants: Anyone is eligible for the prize who agrees to all contest rules. Contestants may be MJFF funded or not and can be from either academia or industry.

Contest rules:

  1. Contestants must apply for the prize with pre-clinical and clinical data supporting the broad use of their alpha-synuclein radiotracer. Judges may ask for additional data, including but not limited to raw imaging data.
  2. NOTE: All contestants must agree to make the winning radiotracer available for use by The Michael J. Fox Foundation and MJFF awardees through a nonexclusive license or other MJFF-approved mechanism.

Criteria for winning: The winning contestant must demonstrate that the radiotracer binds with relatively high selectivity to alpha-synuclein according to pre-specified criteria and must demonstrate proof-of-concept in human subjects, including people with Parkinson's disease and/or another synucleinopathy. See below for more details on submission requirements.

Timeline: There is no deadline for submissions. The $2 million award will be issued to the first contestant who submits compelling evidence of a viable selective tracer and agrees to its widespread use. If no award is given by mid-2018, The Michael J. Fox Foundation will evaluate the state of the field and utility of such a prize.


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January 2019 articles:
Clinical Research Annual Reports
Change in JHM IRB Review Fees for Commercially-Funded Studies
Data and Safety Monitoring Board Training Manual Now Available
Good Clinical Practice (GCP) Fundamentals: Understanding and Applying GCP to Human Subject Research
Fee Schedule Adjustment for Hospital Services Charged to Clinical Trial Budgets
Change in Federalwide Assurance [FWA] Numbers
Changes to NIH-funded Human Subjects Research
Free Resources for Longitudinal Clinical Research Studies
NIH Requirement for Single IRB (sIRB)
JHM IRB Reliance Requests
Sharing Partnership for Innovative Research in Translation
Johns Hopkins Institute for Clinical and Translational Research
Johns Hopkins Clinical Research Network
 
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement
Health, Safety, and Environment (HSE) presents: Safety in Research Updates
Johns Hopkins University | Emerson Collective Cancer Research Fund Request for Proposals
Michael J. Fox Foundation (MJFF) Challenge
Disclosure of Payments from Foreign Educational Institutions and Government Agencies
New Institutional Letter of Support Required for Institutional Training Grant Applications
Notice to the Johns Hopkins Community Regarding the National Science Foundation Grant Reporting Requirement for Harassment Findings and Actions
Prohibited Mention of Prior Review for New Replacement Applications
NIH Policy on Foreign Component Involvement
Why Project Outcomes Matter in your Interim and Final Research Performance Progress Report (RPPR)
NIH Matchmaker, A Tool For Finding Similar NIH Projects
NIH Video Tutorials on How to Apply for Grants

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