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November 2018
FUNDING OPPORTUNITIES- Back

Mallinckrodt Scholar Award

Internal deadline: December 4, 2018

The Edward Mallinckrodt, Jr. Foundation is a private foundation that funds basic biomedical research in St. Louis and throughout the United States. The mission of the Foundation is to support early stage investigators engaged in biomedical research that has the potential to significantly advance the understanding, diagnosis, or treatment of disease. Each year, institutions are invited to submit candidates for the Mallinckrodt Scholar Award. The institutions are selected by the Mallinckrodt Board based on their history of quality grant applications and award selection.

Eligibility & Requirements:

  • PI must hold a M.D. and/or PhD degree(s)
  • PI must be in their fifth to eighth year of a tenure-track position, with support to move the project forward to the point where other independent funding can be obtained
  • Candidates may have an R01

Internal Nomination Process:

Interested applicants should submit the following documents to foundationrelations@jhu.edu:

  1. JHU Limited Submission Cover Sheet
  2. Proposal (maximum of two pages of text only, single spaced: 12-pt font and one-inch margins) (Note: figures, tables, and other reference material may be included in addition to the 2 pg. text limit)
  3. Biosketch of investigator, including current external research support and publications
  4. Budget (two pages maximum)


National Science Foundation (NSF) Major Research Instrumentation Program (MRI) Instrument Acquisition or Development

Internal deadline: December 4, 2018

Opportunity Summary:
The goal of the Major Research Instrumentation (MRI) Program is to increase access to shared-use/multi-user instrumentation for scientific and engineering research and research training. MRI is intended to be a capacity-building program that builds research capabilities across diverse institution types (institutions of higher education and not-for-profit scientific/engineering research organizations). An MRI research instrument need not be physically located in a conventional laboratory setting, nor does an instrument need to be "physical" at all. MRI continues to support distributed/networked instruments and cyberinstrumentation that is not appropriate for support through other NSF programs.

Instrument Acquisition: An MRI acquisition proposal is characterized by a purchase or upgrade of a generally available, yet sophisticated, instrument with little or no modification and risk.

Instrument Development: A development proposal should demonstrate the need for a new or extensively upgraded instrument with new performance, enabling enhanced or potentially transformative research opportunities, open up new areas of research and research training and/or have potential as a commercial product.

Any MRI proposal may request support for either the acquisition or development of a research instrument.

  • Track 1: Track 1 MRI proposals are those that request funds from NSF greater than or equal to $100,000 and less than $1,000,000.
  • Track 2: Track 2 MRI proposals are those that request funds from NSF greater than or equal to $1,000,000 up to and including $4,000,000.

Eligibility & Requirements:

  • No PI limits.
  • The MRI program will not accept proposals for an instrument that augments an NSF Major Research Equipment and Facilities Construction (MREFC) project unless the project is receiving operations funding outside of the MREFC account.
  • Proposals for the acquisition or development of an instrument involving another Federal agency or one of their Federally Funded Research and Development Centers (FFRDCs) [4] must be submitted as a consortium proposal by an MRI submissioneligible organization as described in item 3(b) under "Eligibility Information".
  • The MRI Program does not provide support for instrumentation to be used in medical education (such as medical school courses).
  • Track 1 requests from NSF for less than $100,000 will be accepted only for disciplines of mathematics or social, behavioral and economic sciences.

Internal Nomination Process:
Interested applicants should send the following documents:

  1. JHU Limited Submission Cover Sheet
  2. Proposal (maximum of two pages of text only, single spaced: 12-pt font and one-inch margins) (Note: figures, tables, and other reference material may be included in addition to the 2 pg. text limit)
  3. Curriculum Vitae of investigator, including current external research support and publications
  4. Budget (two pages maximum).

Apply here and contact resapp@jhu.edu with any questions.


Michael J. Fox Foundation (MJFF) Challenge

No application deadline

The Michael J. Fox Foundation is sponsoring a $2 million prize to the first team to develop a viable selective alpha-synuclein PET tracer and agree to make that tracer available broadly.

The ability to image alpha-synuclein deposition in the brain would be a game-changing achievement for the Parkinson's disease (PD) field. The accumulation of aggregated alpha-synuclein is a pathological hallmark of PD and a priority target for drug development given its hypothesized contribution to neurodegeneration. In vivo imaging of alpha-synuclein pathology could be useful as a biomarker of the presence of disease and disease progression and as a pharmacodynamic tool for drug development. With this prize, the Foundation seeks to attract research teams and accelerate momentum to speed the development of such a tracer.

Contestants: Anyone is eligible for the prize who agrees to all contest rules. Contestants may be MJFF funded or not and can be from either academia or industry.

Contest rules:

  1. Contestants must apply for the prize with pre-clinical and clinical data supporting the broad use of their alpha-synuclein radiotracer. Judges may ask for additional data, including but not limited to raw imaging data.
  2. NOTE: All contestants must agree to make the winning radiotracer available for use by The Michael J. Fox Foundation and MJFF awardees through a nonexclusive license or other MJFF-approved mechanism.

Criteria for winning: The winning contestant must demonstrate that the radiotracer binds with relatively high selectivity to alpha-synuclein according to pre-specified criteria and must demonstrate proof-of-concept in human subjects, including people with Parkinson's disease and/or another synucleinopathy. See below for more details on submission requirements.

Timeline: There is no deadline for submissions. The $2 million award will be issued to the first contestant who submits compelling evidence of a viable selective tracer and agrees to its widespread use. If no award is given by mid-2018, The Michael J. Fox Foundation will evaluate the state of the field and utility of such a prize.


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November 2018 articles:
Trends in Clinical Research Program
Clinical Research Annual Reports
Change in JHM IRB Review Fees for Commercially-Funded Studies
Data and Safety Monitoring Board Training Manual Now Available
Good Clinical Practice (GCP) Fundamentals: Understanding and Applying GCP to Human Subject Research
Fee Schedule Adjustment for Hospital Services Charged to Clinical Trial Budgets
Change in Federalwide Assurance [FWA] Numbers
Changes to NIH-funded Human Subjects Research
Free Resources for Longitudinal Clinical Research Studies
NIH Requirement for Single IRB (sIRB)
JHM IRB Reliance Requests
Sharing Partnership for Innovative Research in Translation
Johns Hopkins Institute for Clinical and Translational Research
Johns Hopkins Clinical Research Network
 
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement
Health, Safety, and Environment (HSE) presents: Safety in Research Updates
Mallinckrodt Scholar Award
National Science Foundation (NSF) Major Research Instrumentation Program (MRI) Instrument Acquisition or Development
Michael J. Fox Foundation (MJFF) Challenge
NIH Loan Repayment Programs - Action required by November 9
Prohibited Mention of Prior Review for New Replacement Applications
NIH Policy on Foreign Component Involvement
Why Project Outcomes Matter in your Interim and Final Research Performance Progress Report (RPPR)
NIH Matchmaker, A Tool For Finding Similar NIH Projects
NIH Video Tutorials on How to Apply for Grants

This Month's Departmental Listings

Upcoming Deadlines for November, December and January

November Events at the Genetic Resources Core Facility
       

 

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