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September 2018

SANOFI Innovation Awards Program

Internal deadline: September 15, 2018

Johns Hopkins University School of Medicine and sixteen other major peer institutions (Brigham and Women’s Hospital, Columbia University, Massachusetts General Hospital, Boston Children’s Hospital, University of Pennsylvania, Weill Cornell Medical Center, Stanford University, UCLA, UCSF, New York University, Northeastern University, Children’s Hospital of Philadelphia, Dana Farber Cancer Center, Sinai Health (Toronto), Sunnybrook Health (Toronto) and University Health Network (Toronto)) have entered into an agreement with SANOFI for their fourth Innovations Awards Program. If proposed projects are selected they will receive a one-year award for $125,000 including indirect costs, which may be renewable for an additional year and/or successful Innovation Awards projects may receive additional ongoing sponsored awards beyond the Innovation Program. The Innovation Awards Agreement includes pre-negotiated terms of the Innovation Awards and additional follow-on Sponsored Awards with publication rights for the investigators and an IP option for SANOFI.

To be eligible for consideration, projects will go through a two stage review; 1) first submit to Karen Falter (kjustice@jhmi.edu) a brief non-confidential pre-proposal by September 15, 2018, and 2) SANOFI will select from the pre-proposals those projects that will be asked to prepare a more detailed confidential proposal by October 15th, under guidelines issued at that time. The requested detailed proposals will be due on November 5th and will be reviewed by a Joint Scientific Committee that includes a scientist from each of the participating institutions as well as from SANOFI. Selected awards are expected to be announced early December.

Please submit innovative translational research ideas that align with SANOFI's stated areas of interest in the RFP document. Unfunded previous internal and external proposals and new proposal ideas can be used. Funding Awards are only available for research conducted by researchers at this institution that does not involve a third-party collaborator. A third party-collaborator is considered (i) any researcher employed by an institution or entity that is not an institution/entity participating in the iAwards program, (ii) a funding source involving any organization or entity other than a state or federal government agency, or (iii) a third party for which the confidential information, materials, or methods or models described in the proposal involve third-party rights that may restrict the Parties’ intellectual property rights as set forth in the Funding Award Agreement template.

If you have any questions, please contact Karen Falter (kjustice@jhmi.edu).

9th Annual Mirowski Discovery Award

Application Deadline: Monday, October 1, 2018

The Johns Hopkins University School of Medicine announces a request for applications for the 9th Annual Discovery Fund in honor of Dr. Michel Mirowski and his wife Anna for Cardiovascular Research. This announcement seeks proposals for innovative cardiovascular research projects led by faculty of the Johns Hopkins University School of Medicine (SOM). This award of up to $75,000 is to catalyze innovative ideas that are high risk and would not ordinarily be funded by the NIH until sufficient preliminary data are gathered. This award is not intended to support already established projects or incremental extensions of ongoing research programs. Collaborations across all Johns Hopkins entities are eligible for consideration, but proposals must include a SOM faculty member as principal investigator.

The Mirowski Discovery Award will consist of up to $75,000, with an award term of one year. Applicants must describe a credible plan that they will make substantial progress with one year of funding.

The research proposal should be submitted as one PDF and contain the following:

  1. Limited submission form
  2. Title
  3. Investigator (departmental and divisional affiliation)
  4. Abstract
  5. Specific Aims
  6. Innovation and Impact
  7. Brief Experimental Plan:
    The research proposal section can be no more than three pages (single-spaced Arial font size 11), not including citations. Citations should be limited to 10. Shorter applications are encouraged. Since the Mirowski Discovery Award is intended for new collaborative projects, no preliminary data are required.
  8. A budget description that describes how the funding will be allocated to each investigator in the collaboration and how it will be apportioned for any personnel, supplies and equipment. A budget amount up to $75,000 can be proposed. Faculty salary and equipment costs can be included or excluded as desired. No indirect costs should be included in the budget.
  9. An NIH-style biosketch for the investigator, without the personal statement, that includes all current and pending support from all sponsored and nonsponsored sources. The biosketch is limited to four pages.

Applications should be submitted to: shayden@jhmi.edu

Michael J. Fox Foundation (MJFF) Challenge

No application deadline

The Michael J. Fox Foundation is sponsoring a $2 million prize to the first team to develop a viable selective alpha-synuclein PET tracer and agree to make that tracer available broadly.

The ability to image alpha-synuclein deposition in the brain would be a game-changing achievement for the Parkinson's disease (PD) field. The accumulation of aggregated alpha-synuclein is a pathological hallmark of PD and a priority target for drug development given its hypothesized contribution to neurodegeneration. In vivo imaging of alpha-synuclein pathology could be useful as a biomarker of the presence of disease and disease progression and as a pharmacodynamic tool for drug development. With this prize, the Foundation seeks to attract research teams and accelerate momentum to speed the development of such a tracer.

Contestants: Anyone is eligible for the prize who agrees to all contest rules. Contestants may be MJFF funded or not and can be from either academia or industry.

Contest rules:

  1. Contestants must apply for the prize with pre-clinical and clinical data supporting the broad use of their alpha-synuclein radiotracer. Judges may ask for additional data, including but not limited to raw imaging data.
  2. NOTE: All contestants must agree to make the winning radiotracer available for use by The Michael J. Fox Foundation and MJFF awardees through a nonexclusive license or other MJFF-approved mechanism.

Criteria for winning: The winning contestant must demonstrate that the radiotracer binds with relatively high selectivity to alpha-synuclein according to pre-specified criteria and must demonstrate proof-of-concept in human subjects, including people with Parkinson's disease and/or another synucleinopathy. See below for more details on submission requirements.

Timeline: There is no deadline for submissions. The $2 million award will be issued to the first contestant who submits compelling evidence of a viable selective tracer and agrees to its widespread use. If no award is given by mid-2018, The Michael J. Fox Foundation will evaluate the state of the field and utility of such a prize.

Return to top of Funding Opportunities

September 2018 articles:
Clinical Research Annual Reports
Change in JHM IRB Review Fees for Commercially-Funded Studies
Data and Safety Monitoring Board Training Manual Now Available
Good Clinical Practice (GCP) Fundamentals: Understanding and Applying GCP to Human Subject Research
Fee Schedule Adjustment for Hospital Services Charged to Clinical Trial Budgets
Change in Federalwide Assurance [FWA] Numbers
Changes to NIH-funded Human Subjects Research
Free Resources for Longitudinal Clinical Research Studies
NIH requirement for Single IRB (sIRB)
JHM IRB Reliance Requests
Sharing Partnership for Innovative Research in Translation
Johns Hopkins Institute for Clinical and Translational Research
Johns Hopkins Research Network
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement
Health, Safety, and Environment (HSE) presents: Safety in Research Updates
SANOFI Innovation Awards Program
NIH Director's Early Independence Award (DP5 - Clinical Trial Optional)
Michael J. Fox Foundation (MJFF) Challenge
Research Administration Training Program for Existing Staff
Why Project Outcomes Matter in your Interim and Final Research Performance Progress Report (RPPR)
NIH Matchmaker, A Tool For Finding Similar NIH Projects
NIH Video Tutorials on How to Apply for Grants
NIH Policy: Foreign Components Added to a Grant to a Domestic or Foreign Organization

This Month's Departmental Listings

Upcoming Deadlines for September, October and November

September Events at the Genetic Resources Core Facility


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