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July 2017
FUNDING OPPORTUNITIES- Back

NIH Directors' Early Independence Awards (DP5)

Internal deadline: July 18, 2017

The NIH Director's Early Independence Awards provide an opportunity for exceptional junior scientists to accelerate their entry into an independent research career by forgoing the traditional post-doctoral training period. Though most newly graduated doctoral-level researchers would benefit by post-doctoral training, a small number of outstanding junior investigators would benefit instead by launching directly into an independent research career. For these select investigators, who have established a record of scientific innovation and research productivity and who have demonstrated unusual leadership, drive, and maturity, post-doctoral training would unnecessarily delay their entry into performing independent research. By the end of the award period, the Early Independence investigator is expected to be competitive for continued funding of his/her research program and for a permanent research oriented position. The NIH Director's Early Independence Awards also provide an opportunity for institutions to invigorate their research programs by bringing in the fresh perspectives of the awardees that they host. Johns Hopkins is invited to make two nominations for this $1,250,000 (in direct costs) award.

Eligibility & Requirements:

  • Given the focus on early research independence, the date of receipt of the terminal doctoral degree or completion of clinical residency of the PD/PI must be between June 1, 2016 and September 30, 2018. The clinical fellowship period is NOT included in the clinical residency or equivalent training period. The date of degree receipt is that which appears on the official transcript for the degree. In addition, at the time of application, the PD/PI must not have served as a post-doctoral fellow following a previous doctoral degree for more than twelve months.
  • At the time of award, either 1) the Early Independence investigator must have received a PhD, MD, DO, DC, DDS, DVM, OD, DPM, ScD, EngD, Dr PH, DNSc, ND (Doctor of Naturopathy), PharmD, DSW, PsyD, or equivalent doctoral degree from an accredited domestic or foreign institution
  • See all eligibility requirements here.

Internal Nomination Process:
Interested applicants should send the following documents in sequence in one PDF to resapp@jhu.edu no later than 4 p.m. on the internal deadline:

  1. JHU Limited Submission Cover Sheet
  2. Proposal (maximum of two pages of text only, single spaced: 12-pt font and one-inch margins) (Note: figures, tables, and other reference material may be included in addition to the 2 pg. text limit)
  3. Curriculum Vitae of investigator, including current external research support and publications
  4. Budget (two pages maximum)
  5. Letter of Recommendation from the Department Chair/Director: Letters of Recommendation can be submitted separately to resapp@jhu.edu stating applicant's name in the subject line).

Each applicant should expect to receive a confirmation of receipt of their materials. Applicants not receiving an acknowledgement, or having any questions, should contact the team via resapp@jhu.edu. For more details on this funding opportunity, view the entire RFA here.


Searle Scholar Fund - Searle Scholars Program

Internal Deadline: July 18, 2017

The Searle Scholars Program is a limited submission award program which makes grants to selected academic and research institutions to support the independent research of outstanding early-career scientists who have recently been appointed as assistant professors on a tenure-track appointment. The Searle Scholars Program Scientific Advisory Board is primarily interested in the potential of applicants to make innovative and high-impact contributions to research over an extended period of time. Applicants for the 2018 competition (awards which will be activated on July 1, 2018) are expected to be pursuing independent research careers in biochemistry, cell biology, genetics, immunology, neuroscience, pharmacology, and related areas in chemistry, medicine, and the biological sciences.

Eligibility & Requirements:

  • Applicants should have begun their appointment as an independent investigator at the assistant professor level on or after July 1, 2016. The appointment must be their first tenure-track position (or its nearest equivalent) at an invited institution.
  • The Searle Scholars Program does not ordinarily support purely clinical research but has supported research programs that include both clinical and basic components. Potential applicants who are unsure if their research is appropriate for our Program are encouraged to examine the research interests of present and former Searle Scholars on this website.
  • Applicants who were nominated for awards in the previous competition year but were not awarded may still meet the eligibility criteria for the current competition.

Internal Nomination Process:
Interested applicants should send the following documents in sequence in one PDF to resapp@jhu.edu no later than 4 p.m. on the internal deadline:

  1. JHU Limited Submission Cover Sheet
  2. Proposal (maximum of two pages of text only, single spaced: 12-pt font and one-inch margins) (Note: figures, tables, and other reference material may be included in addition to the 2 pg. text limit)
  3. Curriculum Vitae of investigator, including current external research support and publications
  4. Budget (two pages maximum)

Each applicant should expect to receive a confirmation of receipt of their materials. Applicants not receiving an acknowledgement, or having any questions, should contact the team via resapp@jhu.edu.
For more information on this opportunity, visit the Searle Scholars Program website.


Department of Defense Peer Reviewed Orthopaedic Research Program (PRORP)

The PRORP will only consider applications that specifically address the critical needs of the orthopaedic research community in one or more of the FY17 Focus Areas. The PRORP will solicit research applications that address at least one of the following FY17 Focus Areas (note that focus area requirements vary by award mechanism):

Surgical Care Focus Areas:

  • Peripheral Nerve Injuries: Treatment strategies to improve outcomes from segmental peripheral nerve defects of motor and mixed (motor and sensory) peripheral nerve damage from crush or complete injury.
  • Prevention of Heterotopic Ossification: Techniques to retard or prevent the development of human post-traumatic heterotopic ossification in the upper extremity.
  • Volumetric Muscle Loss: Techniques to regenerate functional, innervated muscle units in treatment of volumetric muscle loss.
  • Extremity Fractures: Strategies to optimize patient outcomes after extremity fracture (i.e., time to begin rehabilitation, weight-bearing strategy, etc.)
  • Pelvic Ring Injuries: Treatment strategies to improve outcomes of complex pelvic ring injuries.
  • Compartment Syndrome: Strategies to improve current diagnoses for compartment syndrome.
  • Gaps in Clinical Practice Guidelines: Address gaps in current orthopaedic clinical practice guidelines (CPG) and recommendations

(http://www.usaisr.amedd.army.mil/cpgs.html). Applications under this Focus Area must specify which orthopaedically relevant CPG their application is intended to support. Applicants should also highlight the expected impact of their research on orthopaedic clinical practice.

  • Surgical Techniques to Optimize Gait: Validate surgical techniques to optimize gait efficiency and outcomes for patients with amputation or limb salvage.
  • Soft Tissue Trauma: Strategies to develop and/or identify musculoskeletal extremity soft tissue trauma treatments optimizing return to duty, work, or reintegration.
  • Osteoarthritis: Treatment strategies involving large animal studies, clinical research, or clinical trials to improve outcomes of osteoarthritis and/or post-traumatic osteoarthritis.

Rehabilitation Focus Areas:

  • Post-Operative Pain Management: Develop and/or validate strategies for post-operative pain management following orthopaedic trauma that minimize or eliminate opioid use. The primary outcome measures should relate to rehabilitation endpoints and not focus solely on pain scores.
  • Prosthetic and/or Orthotic Device Function: Development and optimization of novel, innovative technologies to improve prosthetic and/or orthotic device function and durability, including intuitive efferent (motor) and afferent (sensory) user interfaces and considerations for interoperability.
  • Secondary Physical Health Effects: Techniques or technologies that improve prediction, identification, and reduction of secondary physical health effects (e.g., obesity, arthrosis, osteoporosis, cardiovascular disease) following severe/high-energy traumatic neuromusculoskeletal non-spinal cord injury. The focus should be on injuries sustained between the ages of 18-50 and secondary physical health effects that develop within 5 years of injury.
  • Physical or Occupational Therapy: Development and/or validation of optimal physical or occupational therapy treatment strategies and sequence of progression throughout the rehabilitation continuum to maximize functional outcomes following severe neuromusculoskeletal injury, excluding central nervous system. Examples include optimal timing, frequency, duration, and intensity of rehabilitation interventions.
  • Barriers to Successful Therapy Outcomes: Identify, quantify, and stratify confounding treatable factors (e.g., pain, sleep, nutrition, compliance, etc.) that inhibit or delay optimal orthopaedic rehabilitation outcomes.
  • Rehabilitation Outcomes: Development and/or validation of standardized measures to objectively assess and improve rehabilitation outcomes, including multi-extremity trauma and/or psychosocial resiliency and reintegration, following neuromusculoskeletal injury.
  • Osteoarthritis: Development and/or validation of optimal physical or occupational therapy treatment strategies to improve outcomes of osteoarthritis and/or post-traumatic osteoarthritis.

Applied Research Award - Preapplication due July 12, 2017
Independent investigators at all academic levels (or equivalent) are eligible to submit applications.

  • Pre-application is required; Full application submission is by invitation only.
  • Supports applied research applications focused on advancing optimal treatment and restoration of function for military personnel with musculoskeletal injuries sustained during combat or combat-related activities.
  • Applications must address one and only one of the FY17 PRORP Focus Areas.
  • Proposed research should be supported by preliminary data and have the potential to make significant advancements toward clinical translation.
  • Applications are highly encouraged to include large animal studies in their research plan, where appropriate.

Clinical trials are not allowed under this award mechanism

  • Maximum funding of $750,000 for total costs
  • Maximum period of performance is 3 years
  • All direct and indirect costs of any subaward (subgrant or subcontract) must be included in the total direct costs of the primary award.
  • The applicant may request the entire maximum funding amount for a project that may have a period of performance less than the maximum 3 years.

Clinical Trial Award - Preapplication due July 12, 2017
Independent investigators at all academic levels (or equivalent) are eligible to submit applications.

  • Pre-application is required; Full application submission is by invitation only.
  • Supports the rapid implementation of clinical trials with the potential to have a major impact on military combat-related orthopaedic injuries, or non-battle injuries that significantly impact unit readiness and return-to-duty/work rates
  • Applications must address one and only one of the FY17 PRORP Focus Areas.
  • Funding must support a clinical trial and may not be used for preclinical research studies.
    Collaboration with military researchers and clinicians is encouraged.
  • Studies that include active duty military or Veteran participants as all or a portion of the study population will be considered.

Investigational New Drug or Investigational Device Exemption applications, if needed, should be submitted to the Food and Drug Administration within 6 months of the award date.

  • Maximum funding of $3 million (M) for direct costs (plus indirect costs)
  • Maximum period of performance is 4 years.
  • All direct and indirect costs of any subaward (subgrant or subcontract) must be included in the total direct costs of the primary award.
    The applicant may request the entire maximum funding amount for a project that may have a period of performance less than the maximum 4 years.

Integrated Clinical Trial Award - Preapplication due July 12, 2017

Independent investigators at all academic levels (or equivalent) are eligible to submit applications.

  • Pre-application is required; Full application submission is by invitation only.
  • Supports the rapid implementation of inter-disciplinary clinical trials with the potential to have a major impact on military combat-related orthopaedic injuries, or non-battle injuries that significantly impact unit readiness and return-to-duty/work
  • Applications must address at least two (minimum of one Surgical Care and one Rehabilitation) and a maximum of four of the FY17 PRORP Focus Areas.
  • Required Qualified Collaborator: To encourage meaningful and productive multidisciplinary collaborations, there must be at least one investigator with rehabilitation expertise and at least one clinician who specializes in orthopaedic or trauma care.
  • Collaboration with military researchers and clinicians is encouraged.
  • Studies that include active duty military or Veteran participants as all or a portion of the study population will be considered.

Investigational New Drug or Investigational Device Exemption applications, if needed, should be submitted to the Food and Drug Administration within 6 months of the award date.

  • Maximum funding of $4.5M for direct costs (plus indirect costs)
  • Maximum period of performance is 4 years.
  • All direct and indirect costs of any subaward (subgrant or subcontract) must be included in the total direct costs of the primary award.

The applicant may request the entire maximum funding amount for a project that may have a period of performance less than the maximum 4 years.

Clinical Translational Research Award - Preapplication due July 12, 2017
Independent investigators at all academic levels (or equivalent) are eligible to submit applications.

  • Pre-application is required; Full application submission is by invitation only.
  • Supports research that evaluates the effectiveness of health care practices and/or interventions with potential to impact the standard of care and contribute to evidence-based guidelines for the evaluation and care of Military or Veteran amputee and/or limb salvage patients.
  • Applications must address one and only one of the FY17 PRORP Rehabilitation Focus Areas.
  • Funding must support clinical research studies involving humans.
  • Preliminary or published data relevant to the proposed research project are required.
  • Collaboration with military researchers and clinicians is encouraged.
  • Studies that include active duty military or Veteran participants as all or a portion of the study population will be considered.

Investigational New Drug or Investigational Device Exemption applications, if needed, should be submitted to the Food and Drug Administration within 6 months of the award date.

  • Maximum funding of $2M for direct costs (plus indirect costs)
  • Maximum period of performance is 4 years.
  • All direct and indirect costs of any subaward (subgrant or subcontract) must be included in the total direct costs of the primary award.

The applicant may request the entire maximum funding amount for a project that may have a period of performance less than the maximum 4 years.

A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final Program Announcements and General Application Instructions available for electronic downloading from the Grants.gov website. The application package containing the required forms for each award mechanism can also be found on Grants.gov. A listing of all CDMRP funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.


AHA Institute for Precision Cardiovascular Medicine

Uncovering New Patterns Grants

  • One-year grants to uncover new patterns and make new discoveries within and across existing datasets using cloud computing. Specifically, these grants will target the areas of data harmonization, testing new methods, identifying new biomarkers, and testing new hypothesis for as-of-yet unsolved problems in existing datasets.
  • $150,000 award amount.
  • DEADLINE EXTENDED: Thursday, August 24, 2017
  • Read the Institute Uncovering New Patterns Grant RFA (PDF)

Uncovering New Patterns Fellowships

  • Two-year fellowships to train a generation of postdoctoral fellows in the scientific area of cardiovascular diseases and stroke and cloud computing. Specifically, these grants will target the areas of data harmonization, testing new methods, identifying new biomarkers, and testing new hypothesis for as-of-yet unsolved problems in existing datasets.
  • $150,000 award amount.
  • DEADLINE EXTENDED: Thursday, August 24, 2017
  • Read the Institute Uncovering New Patterns Fellowships Grant RFA (PDF)


Sol Goldman Pancreatic Cancer Research Center Funding

The Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins is pleased to announce that funding is available for a limited number of novel developmental research programs (pilot projects) in the study of adenocarcinoma of the pancreas. This program funds important new pilot projects with promising translational potential that do not have sufficient data for an independently funded NIH grant. Projects of high priority should focus on new research directions, explore innovative ideas, test unconventional, but potentially important, new hypotheses, or ascertain the feasibility of new research approaches. Applications are due Thursday, August 31, 2017 at 5:00 p.m. Access application instructions and download application forms at: http://pilotprojects.onc.jhmi.edu.


Under Armour Women's Health & Breast Cancer Innovation Grant

Deadline: September 1, 2017

The Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Johns Hopkins and Under Armour are pleased to announce a continuation of the funding opportunity for Innovation Grants. Under Armour has gifted $1 million to the Johns Hopkins Breast Cancer Program for applications seeking seed funding that explore dynamic and innovative ways to help empower patients in their care, seek new and novel approaches to determine risk, or provide prevention and treatment strategies, patient engagement & empowerment and overall well-being. Applications can be in any area of research or patient care but should follow the mission of unique, innovative ideas that will lead to a change in the paradigm of women's health as related to breast cancer. A total of 10 grants will be awarded at $100,000 each (direct costs only). Two grants were awarded during the first cycle (December 1, 2015), 3 in the second cycle (June 1, 2016), 2 in the third cycle (December 1, 2016).

Under Armour's mission is "To Make All Athletes Better through passion, design and the relentless pursuit of innovation." Building upon this mission, faculty leveraging collaborations that consider efforts utilizing new and novel technologies are encouraged, as well as projects that allow the gathering of preliminary data to support innovative ideas with potential to shift paradigms in breast cancer and women's health as related to breast cancer. Applications which have entrepreneurial potential are particularly encouraged.

Eligibility Criteria:

  1. All tenure track JHU faculty members are eligible to apply.
  2. All research and or training support must be associated with the advancement of or innovation toward breast cancer and/or women's health as related to breast cancer.
  3. Proposals are encouraged to include multidisciplinary collaboration involving two or more academic divisions partnering together on research opportunities.
  4. Proposals should encompass efforts to be complete in a period no greater than 12 months.
  5. Translational impact for patient care is a requirement for applications. Faculty are encouraged to discuss with clinical oncology faculty the merits of their application for this criterion. Help in identifying individuals to discuss translational impact will be available upon request.

Funds Usage:

  • Funds may be used only to support research costs. Funds cannot be used for salary support and/or equipment.

Deliverable Requirement:

  • Research findings of awardees to be presented at a scientific retreat of all investigators and key personnel at JH and Under Armour.
  • A short final progress report with financial report at the end of the funding period.

Submission Requirements:

  • Title page to include:
    • Title of proposed research
    • Principal investigator information: name, academic rank, department, office address, phone number, email address
    • Co-PIs and other Key personnel (Co-investigators, collaborators, etc.)
    • Other Faculty information as requested
  • Submissions should include the following sections:
    • Lay Summary
    • Specific aims
    • Innovation
    • Significance
    • Background
    • Experimental Design
    • Long term goal and timeline
    • References
  • Format: 3-page limit (not including title page or references), single-space, 1 inch margins, 11 point, Arial font. Use this template. Please send submission as one PDF.
  • Please attach NIH biosketch (5 page max, each) for the PI and key investigators.
  • Proposals (PDF) should be sent to Kristen Wagner-Smith via email kwagner4@jhmi.edu by 5pm on September 1, 2017.


Michael J. Fox Foundation (MJFF) Challenge

No application deadline

The Michael J. Fox Foundation is sponsoring a $2 million prize to the first team to develop a viable selective alpha-synuclein PET tracer and agree to make that tracer available broadly.

The ability to image alpha-synuclein deposition in the brain would be a game-changing achievement for the Parkinson's disease (PD) field. The accumulation of aggregated alpha-synuclein is a pathological hallmark of PD and a priority target for drug development given its hypothesized contribution to neurodegeneration. In vivo imaging of alpha-synuclein pathology could be useful as a biomarker of the presence of disease and disease progression and as a pharmacodynamic tool for drug development. With this prize, the Foundation seeks to attract research teams and accelerate momentum to speed the development of such a tracer.

Contestants: Anyone is eligible for the prize who agrees to all contest rules. Contestants may be MJFF funded or not and can be from either academia or industry.

Contest rules:

  1. Contestants must apply for the prize with pre-clinical and clinical data supporting the broad use of their alpha-synuclein radiotracer. Judges may ask for additional data, including but not limited to raw imaging data.
  2. NOTE: All contestants must agree to make the winning radiotracer available for use by The Michael J. Fox Foundation and MJFF awardees through a nonexclusive license or other MJFF-approved mechanism.

Criteria for winning: The winning contestant must demonstrate that the radiotracer binds with relatively high selectivity to alpha-synuclein according to pre-specified criteria and must demonstrate proof-of-concept in human subjects, including people with Parkinson's disease and/or another synucleinopathy. See below for more details on submission requirements.

Timeline: There is no deadline for submissions. The $2 million award will be issued to the first contestant who submits compelling evidence of a viable selective tracer and agrees to its widespread use. If no award is given by mid-2018, The Michael J. Fox Foundation will evaluate the state of the field and utility of such a prize.


Return to top of Funding Opportunities

 
   
July 2017 articles:
Training Sessions: Preparing for NIH's Single IRB Review Requirement
Free Resources for Longitudinal Clinical Research Studies
New Fee Schedule for Commercially Funded Studies
NIH requirement for Single IRB (sIRB)
JHM IRB Reliance Requests
Johns Hopkins Institute for Clinical and Translational Research
Johns Hopkins Research Network
JHM HSR Recertification Training
 
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement
Health, Safety, and Environment (HSE) presents: Safety in Research Updates
NIH Directors' Early Independence Awards (DP5)
Searle Scholar Fund - Searle Scholars Program
Department of Defense Peer Reviewed Orthopaedic Research Program (PRORP)
AHA Institute for Precision Cardiovascular Medicine
Sol Goldman Pancreatic Cancer Research Center Funding
Under Armour Women's Health & Breast Cancer Innovation Grant
Michael J. Fox Foundation (MJFF) Challenge
NIH Video Tutorials on How to Apply for Grants
NIH Policy: Foreign Components Added to a Grant to a Domestic or Foreign Organization

This Month's Departmental Listings

Upcoming Deadlines for July, August and September

July Events at the Genetic Resources Core Facility
       

 

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