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Clinical Trials

We are constantly researching future treatments for liver and pancreatic cancers, including the role of immunotherapy. Our center has a number of clinical trials for which we are recruiting patients. Learn more about our open trials

Clinical Trial TitlePrimary InvestigatorCo-Investigator(s)
Changes in Biomarkers From Blood Over Time in Patients With Pancreatic AdenocarcinomaChristopher Wolfgang, M.D.Martin Makary, M.D.; Jin He, M.D.; Richard Burkhart, M.D.; Jun Yu, M.D.
Pilot study to determine feasibility of using ICG dye and SPY cam to observe lymphatic drainage in patients undergoing pancreatic surgery for pancreatic tumorsChristopher Wolfgang, M.D.Martin Makary, M.D.; Jin He, M.D.
A pilot study to assess the feasibility of obtaining genetic signatures by next generation sequencing of fine needle aspirates from patients with resectable pancreatic cancerChristopher Wolfgang, M.D.Martin Makary, M.D.; Jin He, M.D.
Prospective evaluation of the use of NLR (neutrophil to lymphocyte ratio) as a predictor of malignant transformation of Intraductal papillary mucinous neoplasmChristopher Wolfgang, M.D.Martin Makary, M.D.; Jin He, M.D.
Clinical Correlates to Pancreatic and Peripancreatic TumorsChristopher Wolfgang, M.D.Michael Goggins, M.D.Martin Makary, M.D.; Jin He, M.D.
Evaluation of a Novel Optical Modality to Diagnose and Evaluate Pancreatic TumorsChristopher Wolfgang, M.D.Xingde Li, Ph.D.Martin Makary, M.D.; Jin He, M.D.
Prospective Trial Evaluating the Effect of Closed Suction Drainage Versus Straight Drainage After Distal  Pancreatectomy Christopher Wolfgang, M.D.;  Martin Makary, M.D.; Jin He, M.D.
A randomized control trial of Prevena Peel & Place Dressing versus standard closure for patients undergoing pancreaticoduodenectomy who have undergone neoadjuvant chemotherapy or biliary stent placement Christopher Wolfgang, M.D.; Martin Makary, M.D.; Jin He, M.D.
Prospective Chart Review of Aggressive Multimodal Therapy in Stage IV Pancreatic Cancer Christopher Wolfgang, M.D.; Martin Makary, M.D.; Jin He, M.D.
Patient-Centered Outcomes Research Institute Clinical Effectiveness Research  
The prognostic values of ZIP4 and related catabolic pathway in patients with pancreatic cancerJin He, M.D.Christopher Wolfgang, M.D.; Martin Makary. M.D.
A021501 Preoperative Extended Chemotherapy vs. Chemotherapy Plus Hypofractionated Radiation Therapy for Borderline Resectable Adenocarcinoma of the Head of the PancreasJin He, M.D.Christopher Wolfgang, M.D.Martin Makary, M.D.
Changes in Biomarkers from Blood Over Time in Patients with Colorectal Cancer with liver metastasisJin He, M.D.Christopher Wolfgang, M.D.; Martin Makary, M.D.
Multiple Institutional Borderline TrialJHH and MGHChristopher Wolfgang, M.D.; Martin Makary, M.D.; Jin He, M.D.; Richard Burkhart, M.D.
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