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Sibley Memorial Hospital

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About Urologic Oncology

At Sibley Memorial Hospital, urologic oncology patients have access to the world-class care and expertise of Johns Hopkins Medical Institute. Whatever the symptoms, Sibley’s experts can help diagnose, stage and treat a wide range of problems.

What is urologic cancer?

Urologic cancer is any of the cancers affecting the genitourinary tract, including kidney, ureter, bladder, urethra and penile cancer.

In the modern age, majority of these cancers are diagnosed incidentally. Early detection and treatment is essential to a successful course of treatment, and our oncologists use a number of methods to detect early-stage urological cancer:

Risk Factors

  • Smoking
  • Age
  • Chemical Exposure
  • Previous cancer treatment medications
  • Chronic inflammation
  • Family history


  • Blood in urine
  • Difficulty urinating
  • A palpable mass or enlargement of the testis
  • Small lesions or ulcers in the penile/groin area


At Sibley, we employ a wide range of detection methods that can be used to detect and stage disease, including:

  • Biopsy
  • Endoscopy
  • Imaging
  • Blood tests


A wide range of cancers are treated by the Sibley urologic oncology team. Some of the most common of these are:

Bladder Cancer

Depending on whether the cancer is muscle invasive or non-invasive, bladder cancer treatments differ. Non-muscle invasive cancers can be treated with cystoscopic removal with or without a follow-up intravesical treatment. Muscle-invasive cancers are best treated with cystectomy and reconstruction of urinary reservoir (continent or incontinent).

Prostate Cancer

Insidious cancer can be subject to active surveillance. Intermediate type cancers can be treated with surgery or radiation with or without hormonal therapy. Advanced and metastatic cancers need systemic treatment with hormonal therapy or chemotherapy.

Kidney Cancer

Nephron-sparing surgery, where only part of the kidney is removed, can be considered for most kidney neoplasms. Surgery offers the only chance for a lasting cure of kidney cancer.

Other Urologic Cancers

Sibley's physicians also specialize in the care and treatment of more uncommon urologic cancers, including:

  • Adrenal
  • Testis
  • Penile

Learn about Bladder Cancer with Armine Smith, M.D.

Armine Smith, M.D., director, urologic oncology at Sibley answers questions about bladder cancer, diagnosis and treatment options available.