Human Stem Cell and Related Research

Human Stem Cell and Related Research Guidance

There are several resources and processes for faculty conducting Human Stem Cell and related research at The Johns Hopkins University.

Committees and Related Entities

Due to the nature of human stem cell and related research, a Principal Investigator (PI) may need to submit more than one application. In addition, related committees may need to review research proposals to confirm they meet current safety, ethical, and administrative requirements.

Below are links to charts that briefly describe the function of committees/entities with oversight responsibilities for some human stem cell and research, which types of research they oversee, and related links. In addition, there are some examples of potential proposed research and how the application may flow through the approval process.

Be aware that the following guides were formulated relevant to the JHU SOM. Researchers from other JHU faculties may also find this guide helpful, but know that certain processes or points of contact may differ.

Committee and Entity Chart

Committees and entities are categorized into Primary Oversight Committees, Ancillary Committees, and Institutional Agreement Entities.

  • Primary Oversight Committees are PI-facing and require direct submission of materials from the PI. 
  • Ancillary Committees are generally triggered as applicable through the eIRB or eISCRO application and evaluate relevant parts of the research proposal internally. In some cases, submission of materials to an ancillary committee may be required. 
  • A PI might interact with an Institutional Agreement Entity for matters pertaining to contracts, grants, agreements, and procurement of commercial materials.

Example Scenarios

The example scenarios may be used to understand how certain reviews may be triggered and which applications should be submitted. Proposed actions or items that may trigger a review are underlined and color coded, which corresponds to the color of the respective committee or entity on the chart. Included are also explanations of why such an item may trigger a review and which entity or committee such a review’s jurisdiction falls under. Note that the examples are hypothetical and should be used for reference only.

 

Relevant Policies, Documents, and Resources