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Displaying 1 to 3 of 3 results for type 1 diabetes

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  • Aniket Sidhaye Lab

    Investigators in the Aniket Sidhaye Lab focus on the mechanism of nuclear hormone receptor action—with an emphasis on thyroid hormone receptors and PPAR-gamma obesity—and transitional care of patients with type 1 diabetes.

    Research Areas: biochemistry, obesity, hormones, diabetes, transitional care, endocrinology, thyroid

    Lab Website

    Principal Investigator

    Aniket Sidhaye, M.D.

    Department

    Medicine

  • The Hamad Lab

    Our research interest is crystalized into three main areas:
    1. Type-1 diabetes - Our focus is on understanding how the Fas death pathway regulates the disease and how extracted information can be used to protect high risk individuals and those with new-onset disease.
    2. Type 2 diabetes and Obesity - Our lab is studying the role of heparan sulfate proteoglycans (HSPG) in regulating body fat and glucose clearance.
    3. Double negative ??T cells - Our studies suggest a critical role for these cells in protecting kidneys from Ischemia reperfusion injury (IRI). Our current focus is understanding their origin and physiological functions.

    Research Areas: type 1 diabetes, type 2 diabetes, obesity, Double negative alpha/beta T cells, T cells

    Lab Website

    Principal Investigator

    Abdel-Rahim Hamad, M.V.Sc., Ph.D.

    Department

    Pathology

  • Thomas W. Donner Lab

    The Thomas W. Donner Lab focuses on type 1 and type 2 diabetes, with an emphasis on the prevention of complications in patients with these conditions. We’re currently collaborating with Dr. Abdel Hamad to inhibit B-regulatory cell apoptosis through a novel monoclonal antibody that targets the probable apoptotic factor. We also lead a multi-center, international consortium of researchers studying ways to prevent type 1 diabetes and preserve insulin secretion in people who have been recently diagnosed with the chronic condition.

    Research Areas: cell apoptosis, insulin, diabetes

    Principal Investigator

    Thomas Donner, M.D.

    Department

    Medicine

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