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Courtney Robertson Lab
Work in the Courtney Robertson Lab is focused on identifying interventions that could minimize the neurological deficits that can persist after pediatric traumatic brain injury (TBI). One study used a preclinical model to examine potential disruption of mitochondrial function and alterations in cerebral metabolism. It was found that a substantial amount of mitochondrial dysfunction is present in the first six hours after TBI. In addition, we are using nuclear magnetic resonance spectroscopy to evaluate global and regional alterations in brain metabolism after TBI. We're also collaborating with researchers at the University of Pennsylvania to compare mitochondrial function after head injury in different clinically relevant models.
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The Koliatsos Lab
Founded in the late 1980s, our Lab has been exploring the fundamental mechanisms of neural responses to traumatic and degenerative signals as well as mechanisms of neural repair. Our current interests include: traumatic brain injury and models; mechanisms and treatments of traumatic axonopathies; molecular neuropathology of traumatic brain injury; induced pluripotent stem cells as models of disease.
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