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Johns Hopkins Neuromyelitis Optica (NMO) Clinic
The Johns Hopkins NMO Clinic launched in July 2009 and now follows 210 patients with NMO or NMO Spectrum Disorder (last count March 31, 2014), along with 81 patients with idiopathic transverse myelitis, 45 patients with recurrent transverse myeltis and small handful with recurrent optic neuritis. We also follow a few patients with multiple sclerosis who thought they might have NMO.
Until 2005, 90% of NMO patients were misdiagnosed as multiple sclerosis and treated with medications that did not help. We've become much better at identifying NMO and treating it correctly. Whereas 30% of patients used to be blind or paralyzed within 5 years of diagnosis, now > 70% of our patients are remission without any progression of disease using safe medications.
Dr. Michael Levy directs the NMO Clinic and sees NMO patients in clinic every other Monday. He completed the MD/PhD program at Baylor College of Medicine in Houston, TX (where he grew up), and trained in the neurology residency and fe...llowship programs at Johns Hopkins before joining the faculty in 2009. In addition seeing patients with NMO, Dr. Levy also runs clinical trials in NMO (see the clinical trials page) and runs a basic science laboratory devoted to the finding the cure to NMO.
Maureen Mealy, RN, is the program director for the Johns Hopkins Transverse Myelitis Center and the NMO Clinic. Maureen graduated from the University of Maryland and obtained her nursing degree from the Johns Hopkins School of Nursing. She has 7 years of experience in neurocritical care nursing and 6 years of experience working with patients with NMO.
Regina Brock-Simmons, RN, is the clinical coordinator for all of the trials in NMO. While Regina is relatively new to NMO, she has 10 years of experience running clinical trials at Johns Hopkins and is also trained in phlebotomy and infusions. view less
The research activities of the Neuroimmunopathology Laboratory focus on studies of immunological and molecular mechanisms involved in the pathogenesis of neurological disorders. Our main areas of research include studies of neurological complications of HIV infection and AIDS, multiple sclerosis, transverse myelitis, autism and epilepsy. We seek to explore and identify immunopathological mechanisms associated with neurological disease that may be the target of potential therapeutic interventions. The laboratory collaborates with other researchers and laboratories at Johns Hopkins and other institutions in projects related with studies of the interaction between the immune and central nervous systems in pathological processes leading to neurological dysfunction.
The Calabresi Lab is located in the department of Neurology at the Johns Hopkins University School of Medicine. Our group investigates why remyelination occasionally fails following central nervous system demyelination in diseases like multiple sclerosis. Our primary focus is on discovering the role of t-cells in promoting or inhibiting myelination by the endogenous glial cells.