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Displaying 11 to 20 of 25 results for pulmonary medicine

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  • Jonathan Orens Lab

    Research in the Jonathan Orens Lab examines topics such as clinical outcomes of lung transplantation, chronic allograft rejection and ischemic reperfusion injury, also known as primary graft dysfunction.

    Research Areas: ischemia-reperfusion injury, chronic allograft rejection, pulmonary medicine, lung transplant

    Principal Investigator

    Jonathan Orens, M.D.

    Department

    Medicine

  • Larissa Shimoda Lab

    Research in the Larissa Shimoda Lab focuses on several important topics within pulmonary and critical care medicine. We primarily study pulmonary arterial responses to chronic hypoxia as well as hypoxic pulmonary vasoconstriction and oxidant-mediated lung injury. Our recent research has included investigating the effects of chronic hypoxia on pulmonary circulation and the ways in which hypoxia-inducible factors impact pulmonary vascular responses to hypoxia. We have also studied vascular remodeling in patients with pulmonary hypertension.

    Research Areas: critical care medicine, lung injury, pulmonary medicine, lung disease, hypoxia

    Principal Investigator

    Larissa Shimoda, M.S., Ph.D.

    Department

    Medicine

  • Mark Liu Lab

    Research in the Mark Liu Lab explores several areas of pulmonary and respiratory medicine. Our studies primarily deal with allergic inflammation, chronic obstructive pulmonary disease (COPD) and asthma, specifically immunologic responses to asthma. We have worked to develop a microfluidic device with integrated ratiometric oxygen sensors to enable long-term control and monitoring of both chronic and cyclical hypoxia. In addition, we conduct research on topics such as the use of magnetic resonance angiography in evaluating intracranial vascular lesions and tumors as well as treatment of osteoporosis by deep sea water through bone regeneration.

    Research Areas: respiratory system, pulmonary medicine, asthma, COPD, inflammation, hypoxia

    Principal Investigator

    Mark Liu, M.D.

    Department

    Medicine

  • Noah Lechtzin Lab

    Research in the Noah Lechtzin Lab investigates several important aspects of cystic fibrosis (CF), including the impact of antibiotic-resistant bacterial infections in CF patients and new therapy options for individuals with CF. Our research into new CF therapies has included studies on home electronic symptom and lung function monitoring, transbronchial needle aspiration and bedside percutaneous endoscopic gastrostomy tube placement. We also explore the role of metabolic complications in CF patients by examining how the disease is impacted by factors such as vitamin D deficiency, osteoporosis and testosterone deficiency.

    Research Areas: osteoporosis, cystic fibrosis, pulmonary medicine, metabolism, antibiotic-resistant bacterial infections, testosterone

    Principal Investigator

    Noah Lechtzin, M.D., M.H.S.

    Department

    Medicine

  • Outcomes After Critical Illness and Surgery Group

    The Outcomes After Critical Illness and Surgery Group is focused on understanding and improving patient outcomes after critical illness and surgery. Research projects include improving long-term outcomes research for acute respiratory distress syndrome/acute respiratory failure (ARDS/ARF) patients; examining the long-term outcomes for acute lung injury/acute respiratory distress syndrome (ALI/ARDS) patients; and evaluating the effects of lower tidal volume ventilation and other aspects of critical illness and ICU care on the long-term physical and mental health outcomes of ALI/ARDS patients.

    Research Areas: critical care medicine, acute respiratory distress syndrome, pulmonary medicine, acute lung injury, rehabilitation

    Lab Website

    Principal Investigator

    Dale Needham, M.D., Ph.D.

    Department

    Medicine

  • Pali Shah Lab

    Research in the Pali Shah Lab focuses on lung transplants. Specifically, we’re interested in chronic rejection and quality and safety as they relate to lung transplants.

    Research Areas: health care quality, pulmonary medicine, safety, lung transplant

    Principal Investigator

    Pali Shah, M.D.

    Department

    Medicine

  • Rachel Damico Lab

    Work in the Rachel Damico Lab explores topics within the fields of vascular biology and pulmonary medicine, with a focus on acute lung injury and apoptosis in lung diseases. Our studies have included examining idiopathic and scleroderma-associated pulmonary arterial hypertension, vascular receptor autoantibodies, and the link between inflammation and the Warburg phenomenon in patients with pulmonary arterial hypertension. We have also researched the inhibitory factor of macrophage migration and its governing of endothelial cell sensitivity to LPS-induced apoptosis.

    Research Areas: critical care medicine, acute lung injury, lung disease, vascular biology, apoptosis

    Principal Investigator

    Rachel Damico, M.D., Ph.D.

    Department

    Medicine

  • Robert Wise Lab

    The Robert Wise Lab conducts clinical trials to study chronic obstructive lung diseases (COPD). We investigate inhaled corticosteroids in patients with mild to moderate COPD and the effectiveness of anti-inflammatories in allowing lung growth in mild to moderate asthmatic children. Our research includes exploring the efficacy of various treatments for asthmatic women who are pregnant and of lung-volume reduction surgery for emphysema patients. We also conduct studies of the clinical epidemiology, pathobiology and treatment of interstitial lung disease in patients with scleroderma.

    Research Areas: critical care medicine, emphysema, scleroderma, pulmonary medicine, asthma, lung-volume reduction surgery, COPD

    Principal Investigator

    Robert Wise, M.D.

    Department

    Medicine

  • Sean Agbor-Enoh Lab

    Research in the Sean Agbor-Enoh Lab explores topics within the field of pulmonary medicine. Our team also participates in clinical trials that explore new techniques for diagnosing rejection following an organ transplant. One current study is seeking to develop a new blood test that may be used instead of biopsies to diagnose rejection after transplant.

    Research Areas: transplants, pulmonary medicine, tranplant rejections

    Principal Investigator

    Sean Agbor-Enoh, M.D., Ph.D.

    Department

    Medicine

  • Shyam Sundar Biswal Lab

    xResearch in the Shyam Biswal Lab focuses on therapeutic resistance of cancer due to a gain-of-function mutation in transcription factor Nrf2. Using patient-derived xenografts in humanized immunocompetent mice and GEM models, we aim to understand the mechanisms of oncogenic cooperation and metabolic adaptation in cancer cells. We’re also investigating the systemic and pulmonary effects of air pollution as well as the health effects of recent tobacco products, such as electronic cigarettes and water pipes.

    Research Areas: Nrf2, tobacco use, genetics, cancer, pulmonary medicine, environment, lung cancer

    Principal Investigator

    Shyam Biswal, Ph.D.

    Department

    Medicine

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