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Displaying 1 to 4 of 4 results for pulmonary fibrosis

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  • Edward Chen Lab

    Research efforts in the Edward Chen Lab focus on bleomycin-induced pulmonary fibrosis and granulomatous inflammation as well as clinical and translational studies in sarcoidosis. Our studies have included topics such as the etiologies of sarcoidosis, hylleraas hydride binding energy in diatomic electron affinities, and molecular convergence of neurodevelopmental disorders. We have also investigated the use of quantitative mass spectrometric analysis to better understand the mechanisms of phospho-priming and auto-activation of the checkpoint kinase Rad53 in vivo.

    Research Areas: pulmonary medicine, sarcoidosis, granulomatous inflammation, pulmonary fibrosis

    Principal Investigator

    Edward Chen, M.D.

    Department

    Medicine

  • Maureen Horton Lab

    The Maureen Horton Lab conducts research on pulmonary fibrosis through the use of both preclinical models and human trials. Our studies have helped to develop novel, genetic, tissue-specific models of immune dysfunction, which have aided in defining the immune regulation of fibrosis and in the development of treatment strategies. We have used T-cell skewing immunotherapy to prevent and reverse chemical-induced lung fibrosis and have conducted clinical trials for idiopathic pulmonary fibrosis (IPF), which led to one of the first treatments that helped to improve quality of life in IPF patients.

    Research Areas: interstitial lung diseases, idiopathic pulmonary fibrosis, pulmonary fibrosis, autoimmune diseases, occupational lung diseases, T cells

    Principal Investigator

    Maureen Horton, M.D.

    Department

    Medicine

  • Sonye Danoff Lab

    Research in the Sonye Danoff Lab includes both basic and translational studies of lung fibrosis. We have explored topics such as the role of support measures and palliative care, pulmonary manifestations of Sjogren's syndrome, idiopathic inflammatory myopathies and the treatment of cough in idiopathic pulmonary fibrosis. Our research has also involved investigating the lung as a potential target for the immune reaction in myositis.

    Research Areas: myositis, interstitial lung diseases, Sjogren's syndrome, lung disease, pulmonary fibrosis, autoimmune diseases

    Principal Investigator

    Sonye Danoff, M.D., Ph.D.

    Department

    Medicine

  • Stephen Mathai Lab

    The Stephen Mathai Lab focuses its research on pulmonary medicine. We're particularly interested in scleroderma-associated pulmonary hypertension, pulmonary complications of connective tissue disease, idiopathic pulmonary fibrosis and pulmonary hypertension.

    Research Areas: scleroderma, pulmonary medicine, hypertension, pulmonary fibrosis, connective tissue disease

    Principal Investigator

    Stephen Mathai, M.D., M.H.S.

    Department

    Medicine

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