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Displaying 1 to 27 of 27 results for public health

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  • Alain Labrique Lab

    The Alain Labrique Lab conducts research on infectious diseases and public health. Our team studies the various factors that lead to maternal and neonatal mortality, particularly in underserved populations in South Asia, using the tools of infectious disease epidemiology, molecular biology and biostatistics. We work to better understand factors such as the interface of micronutrient deficiency and maternal/infant mortality and the prevention of nosocomial infections through mechanistic or nutritional interventions. We also have a longstanding interest in technologies that may enable early detection of disease.

    Research Areas: epidemiology, mobile health, Hepatitis, neonatal, infectious disease, public health, biostatistics, nosocomial infections, molecular biology

  • Amita Gupta Lab

    The Amita Gupta Lab focuses on drug trials to prevent and treat HIV, tuberculosis (TB) and other co-morbidities in adults, including pregnant women and children who reside in low-income settings. We also conduct cohort studies assessing HIV, inflammation and nutrition in international settings; TB in pregnancy; and risk factors for TB in India (CTRIUMPH). We collaborate with several faculty in the Center for TB Research, Division of Infectious Diseases and the School of Public Health.

    Research Areas: global health, nutrition, infectious disease, HIV, inflammation, tuberculosis

    Principal Investigator

    Amita Gupta, M.D.

    Department

    Medicine

  • Anderson Lab

    Research in the Anderson laboratory focuses on cellular signaling and ionic mechanisms that cause heart failure, arrhythmias and sudden cardiac death, major public health problems worldwide. Primary focus is on the multifunctional Ca2+ and calmodulin-dependent protein kinase II (CaMKII). The laboratory identified CaMKII as an important pro-arrhythmic and pro-cardiomyopathic signal, and its studies have provided proof of concept evidence motivating active efforts in biotech and the pharmaceutical industry to develop therapeutic CaMKII inhibitory drugs to treat heart failure and arrhythmias.

    Under physiological conditions, CaMKII is important for excitation-contraction coupling and fight or flight increases in heart rate. However, myocardial CaMKII is excessively activated during disease conditions where it contributes to loss of intracellular Ca2+ homeostasis, membrane hyperexcitability, premature cell death, and hypertrophic and inflammatory transcription. These downstream targets a...ppear to contribute coordinately and decisively to heart failure and arrhythmias. Recently, researchers developed evidence that CaMKII also participates in asthma.

    Efforts at the laboratory, funded by grants from the National Institutes of Health, are highly collaborative and involve undergraduate assistants, graduate students, postdoctoral fellows and faculty. Key areas of focus are:
    • Ion channel biology and arrhythmias
    • Cardiac pacemaker physiology and disease
    • Molecular physiology of CaMKII
    • Myocardial and mitochondrial metabolism
    • CaMKII and reactive oxygen species in asthma

    Mark Anderson, MD, is the William Osler Professor of Medicine, the director of the Department of Medicine in the Johns Hopkins University School of Medicine and physician-in-chief of The Johns Hopkins Hospital.
    view more

    Research Areas: heart failure, arrhythmia, cardiovascular diseases, sudden cardiac death

    Lab Website

    Principal Investigator

    Mark Anderson, M.D., Ph.D.

    Department

    Medicine

  • Andrew Lane Lab

    The Lane laboratory is focused on understanding molecular mechanisms underlying chronic rhinosinusitis and particularly the pathogenesis of nasal polyps.  Diverse techniques in molecular biology, immunology, physiology, and engineering are utilized to study epithelial cell innate immunity, olfactory loss, the sinus microbiome, and drug delivery to the nose and sinus cavities. Ongoing work explores how epithelial cells participate in the immune response and contribute to chronic sinonasal inflammation. The lab creates and employs transgenic mouse models of chronic sinusitis to support research in this area. Collaborations are in place with the School of Public Health to explore mechanisms of anti-viral immunity in influenza and rhinovirus, and with the University of Maryland to characterize the bacterial microbiome of the nose and sinuses in health and disease.

    Research Areas: nasal polyps, olfaction, cell culture, transgenic mice, chronic rhinosinusitis, innate immunity, molecular biology

  • Ariel Green Lab

    Research in the Ariel Green Lab focuses on informing and improving decisions surrounding the use of invasive medical technologies for older adults with complex medical diseases. Our long-term goals are to conduct epidemiologic research, create public health initiatives, and help shape policies that improve the lives of older adults.

    Research Areas: epidemiology, health care policy, decision making, gerontology

    Principal Investigator

    Ariel R. Green, M.D., M.P.H., Ph.D.

    Department

    Medicine

  • Bakker Memory Lab

    Research in the Bakker Memory Laboratory is focused on understanding the mechanisms and brain networks underlying human cognition with a specific focus on the mechanisms underlying learning and memory and the changes in memory that occur with aging and disease. We use a variety of techniques including neuropsychological assessments, experimental behavioral assessments and particularly advanced neuroimaging methods to study these questions in young and older adults and patients with mild cognitive impairment, Alzheimer’s disease, Parkinson’s disease and epilepsy.

    Through our collaborations with investigators in both basic science and clinical departments, including the departments of Psychiatry and Behavioral Sciences, Psychological and Brain Sciences, Neurology and Public Health, our research also focuses on brain systems involved in spatial navigation and decision-making as well as cognitive impairment in neuropsychiatric conditions such as schizophrenia, eating disorders, obsessiv...e-compulsive disorders, depression and anxiety. view more

    Research Areas: epilepsy, depression, Parkinson's disease, Alzheimer's disease

  • Casey Overby Lab

    Research in the Casey Overby Lab focuses on the intersection of public health genomics and biomedical informatics. We’re currently developing applications to support the translation of genomic research to clinical and population-based health care settings. We’re also working to develop knowledge-based ways to use big data — including electronic health records — to improve population health.

    Research Areas: public health, genomics, electronic health records, bioinformatics

    Principal Investigator

    Casey Taylor, Ph.D.

    Department

    Medicine

  • Cervical Dysplasia Research Lab

    We are interested in how immune responses occur in the cervix. The focus of our translational research is on developing immune therapies for disease caused by human papillomavirus (HPV). HPV infection causes more cancers than any other virus in the world. Cervical cancer is the most common cancer caused by HPV, and although we have known how to screen for it for over half a century, it remains the second most common cause of cancer death in women. Although the preventive vaccines are a public health milestone, they prevent HPV infections, but are not designed to make immune responses to treat HPV. We are testing different strategies to make immune responses that could treat HPV disease. Our dedicated researchers are working to extend the techniques used in HPV vaccine development to the creation of vaccines targeting other cancers with defined tumor antigens.

    Research Areas: cervical cancer, HPV, cancer vaccines

  • Cochlear Center for Hearing and Public Health

    The Cochlear Center for Hearing and Public Health is dedicated to training clinicians, researchers and public health experts to study and address the impact that hearing loss has on older adults and public health. We aim to make measured local, national and global impacts through a macro level (e.g., public policy legislation), micro level (e.g., programs to deliver hearing care to individuals in a particular community), and everywhere in between (e.g., influential research publications, etc.) to adhere to our center’s overall mission and vision of effectively optimizing the health and function of an aging society and become the premier global resource for ground-breaking research and training on hearing loss and public health.

    Research Areas: otolaryngology, public health, audiology, gerontology, hearing loss, societal perspectives

  • David Dowdy Lab

    The David Dowdy Lab conducts research in the field of infectious disease epidemiology. We use an interdisciplinary approach that involves infectious disease modeling, health economics, classical epidemiology, and operational and implementation science. Much of our work explores the diagnosis and treatment of tuberculosis. We also have a longstanding interest in “translational epidemiology,” with a goal of developing methods to help medical professionals who use epidemiological data make decisions that are in the best interest of patients and public health.

    Research Areas: health economics, epidemiology, infectious disease, tuberculosis

    Principal Investigator

    David Dowdy, M.D., M.Sc., Ph.D., Sc.M.

    Department

    Medicine

  • Elizabeth Selvin Lab

    The Elizabeth Selvin Lab examines the intersection of epidemiology, clinical policy and public health policy. One of our key goals is to use the findings of epidemiologic research to inform the screening, diagnosis and treatment of diabetes, cardiovascular disease and kidney disease. Much of our work looks at biomarkers and diagnostics related to diabetes and diabetes complications. Our findings — linking hemoglobin A1c (HbA1c) to diabetic complications and identifying the role of A1c in diabetes diagnosis — have influenced clinical practice guidelines.

    Research Areas: epidemiology, biomarkers, kidney diseases, obesity, diabetes, health care policy, cardiovascular diseases

    Principal Investigator

    Elizabeth Selvin, M.P.H., Ph.D.

    Department

    Medicine

  • Eric Bass Lab

    Work in the Eric Bass Lab focuses on evidence-based medicine, comparative effectiveness research, and community health partnerships. Our work is closely aligned with the Center for Health Services and Outcomes Research and the Johns Hopkins Evidence-Based Practice Center.

    Research Areas: clinical medicine, research methods, public health, health care policy, evidence-based medicine

    Principal Investigator

    Eric B. Bass, M.D., M.P.H.

    Department

    Medicine

  • Graham Mooney Lab

    Work in the Graham Mooney Lab focuses on the history of public health interventions as well as the impact of public health policies on population health outcomes. Our research includes topics such as the history of public health in the United Kingdom and United States during the 19th and 20th centuries, and the historical geographies of health and medicine. We also explore infectious disease surveillance and control and historical epidemiology and demography.

    Research Areas: epidemiology, infectious disease, public health, history of medicine

    Lab Website

    Principal Investigator

    Graham Mooney, Ph.D.

    Department

    History of Medicine

  • Hadi Kharrazi Lab

    Research in the Hadi Kharrazi Lab focuses primarily on contextualizing clinical decision support (CDS) into population health informatics (PHI) to be used at different HIT levels of managed care, including electronic health records (EHRs) and consumer health informatics (CHI) solutions. Our team has modified and regenerated electronic quality measures (eQM) based on PHI-derived CDS to represent a population aspect of the health quality measurements. Through the Center for Population Health IT (CPHIT) at the Bloomberg School of Public Health, we are pursuing PHI research that provides direct population-based CDS to providers, patients and payers.

    Research Areas: informatics, electronic health records, quality of care

  • IndoUS Clinical Research

    Our IndoUS team, based both in Baltimore and in India, specializes in international clinical research (cohort studies and clinical trials), public health implementation science and education in infectious diseases, HIV/AIDS, tuberculosis (TB), vaccine preventable illnesses, antimicrobial resistant infections, and more recently COVID. Since 2003, our work has been focused primarily on India, where we are engaged in several Indo-JHU and international research collaborations. We partner with several leading medical and research institutions in India (e.g. BJGMC, DY Patil, Hinduja Hospital, KEM, Bharati Vidyapeeth, NIRT, JIPMER, CMC, Medanta, IISER, YRG, IIT), as well as others in sub-Saharan Africa, US and Brazil. We are actively involved in the following consortia: 1) Indo-US Vaccine Action Program sponsored RePORT India TB research consortium, which is funded by the US National Institutes of Health (NIH) and the government of India, Department of Biotechnology. 2) RePORT International T...B Research Consortium, a multilateral global consortia for TB research, 3) US NIH funded multi-country HIV and TB trials consortia of the AIDS Clinical Trials Group (ACTG) and the International Maternal Pediatric Adolescent AIDS Trials Network (IMPAACT) Network, 4) NIH and AmFAR funded IeDea HIV/TB Working Group and the Treat Asia-IeDEA HIV and TB epidemiology databases, and 5) CDC SHEPHERD AMR studies.

    Our group has been awarded research grants from the US NIH, US CDC, UNITAID, Indian government, and several philanthropic foundations to investigate infectious diseases of importance to India and beyond.
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    Research Areas: international health, infectious disease, antimicrobial resistance, HIV, COVID in adults including pregnant women and children, tuberculosis

    Lab Website

    Principal Investigator

    Amita Gupta, M.D.

    Department

    Medicine

  • Jonathan Weiner Lab

    The Jonathan Weiner Lab researches the impact of electronic health records (EHRs), e-health and other health information technology (HIT) on populations, integrated delivery systems and public health agencies.

    Research Areas: primary care, health IT, public health, electronic health records, predictive modeling, quality of care

    Principal Investigator

    Jonathan Weiner, D.P.H.

    Department

    Health Sciences Informatics

  • Larry Chang Lab

    Research in the Larry Chang Lab focuses on innovative, multidisciplinary and pragmatic approaches to impacting the HIV/AIDS pandemic. Our research investigates ways to improve HIV/AIDS care in low- and middle-income settings through strategies that include quantitative methods, qualitative methods, community-based trial designs, and behavioral science and economic evaluations. In addition, we research mobile technologies for health (mHealth) strategies for improving global public health and clinical care, including novel applications for intimate-partner violence intervention, dengue surveillance, and HIV care, surveillance and prevention.

    Research Areas: global health, infectious disease, AIDS, HIV, mHealth

    Principal Investigator

    Larry Chang, M.D., M.P.H.

    Department

    Medicine

  • Marta Hanson Lab

    Research in the Marta Hanson Lab explores the history of Chinese science and medicine, specifically within the late imperial period. Our studies focus on topics such as the history of epidemics and disease in China; the relationship between visual and textual representations in the culture’s medical texts; and imperial, regional and local traditions in Chinese medicine. We also investigate the interaction between vernacular and elite medical knowledge as well as conceptions of space, the body, ethnicity and native-place identity in China.

    Research Areas: China, epidemics, public health, history of medicine

    Principal Investigator

    Marta Hanson, M.A., Ph.D.

    Department

    History of Medicine

  • Mohamed Atta Lab

    Dr. Atta and his research team explore the epidemiological and clinical interventions of a variety of kidney diseases. Our goal is not only to advance the understanding of many kidney diseases but also to capitalize on novel discoveries of basic science to treat a wide range of rare and common kidney disorders.




    • Multi-international observational study of a rare form of amyloid (LECT2 amyloid) to understand its natural history with the ultimate interest of treating this condition.

    • Our group has launched a project investigating the impact of COVID19 on the kidney to identify risk factors influencing outcome across different clinical phenotypes

    • In collaboration with the Division of Infectious Diseases and the School of Public Health, our research has focused on the epidemiology of HIV and kidney disease. We also study clinical markers and contributing factors in the progression of kidney disease, and the association between kidney disease and h...eart disease.

    • Our research group is participating in a multicenter consortium serving as a clinical core site to study the pathogenesis of HIV-associated kidney disease by providing well-characterized clinical specimens and corresponding clinical and laboratory data.

    view more

    Research Areas: kidney diseases, HIV, hepatitis C

    Principal Investigator

    Mohamed Atta, M.B.B.Ch., M.D., M.P.H.

    Department

    Medicine

  • Morgan Grams Lab

    Dr. Morgan Grams and her colleagues are involved in a wide range of clinical research projects applying quantitative methods to multidimensional data to develop actionable clinical indicators. Along with Dr. Josef Coresh, Dr. Grams leads the Chronic Kidney Disease (CKD) Prognosis Consortium, a global consortium of over 200 investigators and >11 million participants (https://ckdpc.org). They have developed and validated several risk calculators that are now widely used in clinical practice (https://ckdpcrisk.org). She holds a joint appointment in the Bloomberg School of Public Health, where she is a member of the Center of Drug Safety and Effectiveness. Her research in pharmacoepidemiology leverages electronic health records from multiple countries to evaluate the risks and benefits of commonly used medications across the spectrum of kidney function. Together with her team, Dr. Grams also focuses on identifying targetab...le pathways or biomarkers that underlie the development of chronic kidney disease using multi-omic approaches.



    Dr. Grams received the 2019 Frederick Brancati Mentoring Award. Currently, four of her mentees are supported by NIH K awards. More of their research can be found here: http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/40940579/?sort=date&direction=descending
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    Research Areas: organ donors, hyperglycemia, biomarkers, chronic kidney disease, health disparities

    Lab Website

    Principal Investigator

    Morgan Grams, M.D., M.H.S., Ph.D.

    Department

    Medicine

  • Nadia Hansel Lab

    Research in the Nadia Hansel Lab investigates the clinical, pathophysiologic and public health aspects of pulmonary diseases, with a focus on asthma and chronic obstructive pulmonary disease (COPD). We have explored how environmental exposures, nutrition and diet, comorbidity and other factors influence the outcomes of diseases such as asthma and COPD.

    Research Areas: airway diseases, immunology, asthma, allergies, lung disease, COPD

    Principal Investigator

    Nadia Hansel, M.D., M.P.H.

    Department

    Medicine

  • Neuro-Oncology Surgical Outcomes Laboratory

    Directed by Debraj “Raj” Mukherjee, MD, MPH, the laboratory focuses on improving access to care, reducing disparities, maximizing surgical outcomes, and optimizing quality of life for patients with brain and skull base tumors.



    The laboratory achieves these aims by creating and analyzing institutional and national databases, developing and validating novel patient-centered quality of life instruments, leveraging machine learning and artificial intelligence platforms to risk-stratify vulnerable patient populations, and designing novel surgical trials to push the boundaries of neurosurgical innovation.



    Our research also investigates novel approaches to improve neurosurgical medical education including studying the utility of video-based surgical coaching and the design of new operative instrumentation.

    Research Areas: medical education, surgical outcomes, neurosurgery, machine learning, access to care, surgical coaching, population health, quality of life, public health, artificial intelligence, oncology, disparities

  • Randall Packard Lab

    The Randall Packard Lab investigates topics in the field of the history of medicine. Our current work seeks to explore the global history of dengue fever. Research is focused on the emergence and global spread of dengue as well as efforts to understand and control the disease. Part of our research involves establishing a better understanding of the complex biological, economic, environmental and social conditions that enabled the disease to rapidly expand worldwide during the 20th century.

    Research Areas: dengue fever, Africa, infectious disease, public health, history of medicine

    Principal Investigator

    Randall Packard, Ph.D.

    Department

    History of Medicine

  • Richard Chaisson Lab

    Research in the Richard Chaisson Lab primarily examines tuberculosis and HIV infection, with specific focus on global epidemiology, clinical trials, diagnostics and public health interventions. Our recent research has involved evaluating a molecular diagnostic test for tuberculosis in HIV patients; observing TB responses during treatment of pulmonary tuberculosis; and examining antiretroviral therapy adherence, virologic and immunologic outcomes in adolescents compared with adults in Southern Africa.

    Research Areas: global health, epidemiology, infectious disease, AIDS, HIV, tuberculosis

    Principal Investigator

    Richard Chaisson, M.D.

    Department

    Medicine

  • Robert Bollinger Lab

    The key research interests in the Robert Bollinger Lab include identifying biological and behavioral risk factors for HIV transmission as well as characterizing the clinical progression and treatment of HIV and related infectious diseases. We also have a long-standing interest in optimizing health care capacity and delivery in settings with limited resources. Our work includes implementing science research projects to explore the effectiveness of initiatives such as task-shifting, clinical education, distance learning and mobile health programs as a way to improve health care in these locations.

    Research Areas: mobile health, international health, infectious disease, HIV, public health, point-of-care diagnostics, tropical medicine, tuberculosis, health care capacity

    Principal Investigator

    Robert Bollinger, M.D., M.P.H.

    Department

    Medicine

  • The Ramanathan Lab

    Chronic rhinosinusitis (CRS) is a leading cause of morbidity globally and is the single most common self-reported chronic health condition and accounts for billions of dollars in health care costs and lost work days annually. Exposure to air pollutants is thought to be a critical modifier of CRS susceptibility. Despite marked reductions in air pollution levels in the United States, the fine particulate component of air pollution (PM2.5) and ultrafine pollutants secondary to traffic continue to remain a recalcitrant issue globally and in the United States. The Ramanathan Lab focuses on studying the role of air pollution (PM2.5) in CRS. In collaboration with scientists at the Bloomberg School of Public Health, we have utilized a state of the art air pollution exposure system to develop a novel mouse model of air pollution induced rhinosinusitis that mimics many of the features of CRS in humans. Our lab uses transgenic mouse models and novel immunologic/genomic techniques to study the mec...hanisms by which PM2.5 causes eosinophilic inflammation and sinonasal epithelial barrier dysfunction. We are also interested in the role of the antioxidant transcription factor, Nrf2, which has shown to stabilize the epithelial barrier and reduce eosinophilia in PM induced rhinosinusitis as a potential therapeutic target. view more

    Research Areas: nasal polyps, Nrf2, sinonasal epithelial barrier function, particulate matter, chronic rhinosinusitis, epithelial damage, Air pollution

  • Wu Lab

    Dr. Wu leads a multi-disciplinary team with collaborators from the Bloomberg School of Public Health, JHU Whiting School of Engineering, and JHU Krieger School of Arts and Sciences. She conducts ongoing investigations with the Multicenter AIDS Cohort Study and Women’s Inter-agency Health Study. Her lab’s goals are to develop, implement, and validate novel imaging-based metrics of cardiac structure and function to improve risk prediction and stratification at the individual patient-level.

    Research Focuses:

    Predictors of Sudden Cardiac Death by Magnetic Resonance Imaging
    Subclinical myocardial disease in people living with HIV
    Individualized risk prediction
    Cardiac structural and mechanical modeling

    Research Areas: AIDS, HIV, risk prediction, myocardial disease

    Principal Investigator

    Katherine Wu, M.D.

    Department

    Medicine

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