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  • Amita Gupta Lab

    Principal Investigator:
    Amita Gupta, M.D., M.H.S.
    Medicine

    The Amita Gupta Lab focuses on drug trials to prevent and treat HIV, tuberculosis (TB) and othe...r co-morbidities in adults, including pregnant women and children who reside in low-income settings. We also conduct cohort studies assessing HIV, inflammation and nutrition in international settings; TB in pregnancy; and risk factors for TB in India (CTRIUMPH). We collaborate with several faculty in the Center for TB Research, Division of Infectious Diseases and the School of Public Health. view more

    Research Areas: global health, nutrition, infectious disease, HIV, inflammation, tuberculosis
  • Andrew Lane Lab

    The Lane laboratory is focused on understanding molecular mechanisms underlying chronic rhinosi...nusitis, particularly the pathogenesis of nasal polyps, as well as inflammation on the olfactory epithelium. Diverse techniques in molecular biology, immunology, and physiology are utilized to study epithelial cell innate immunity, olfactory loss, and response to viral infection. Ongoing work explores how epithelial cells of the sinuses and olfactory mucosa participate in the immune response and contribute to chronic inflammation. The lab creates and employs transgenic mouse models of chronic nasal/sinus inflammation to support research in this area. Collaborations are in place with the School of Public Health to explore mechanisms of anti-viral immunity in influenza and COVID-19. view more

    Research Areas: nasal polyps, immunology, COVID-19, olfaction, cell culture, transgenic mice, chronic rhinosinusitis, innate immunity, neuroscience, molecular biology
  • Ariel Green Lab

    Research in the Ariel Green Lab focuses on informing and improving decisions surrounding the us...e of invasive medical technologies for older adults with complex medical diseases. Our long-term goals are to conduct epidemiologic research, create public health initiatives, and help shape policies that improve the lives of older adults. view more

    Research Areas: epidemiology, health care policy, decision making, gerontology
  • Bakker Memory Lab

    Lab Website

    Research in the Bakker Memory Laboratory is focused on understanding the mechanisms and brain n...etworks underlying human cognition with a specific focus on the mechanisms underlying learning and memory and the changes in memory that occur with aging and disease. We use a variety of techniques including neuropsychological assessments, experimental behavioral assessments and particularly advanced neuroimaging methods to study these questions in young and older adults and patients with mild cognitive impairment, Alzheimer’s disease, Parkinson’s disease and epilepsy.

    Through our collaborations with investigators in both basic science and clinical departments, including the departments of Psychiatry and Behavioral Sciences, Psychological and Brain Sciences, Neurology and Public Health, our research also focuses on brain systems involved in spatial navigation and decision-making as well as cognitive impairment in neuropsychiatric conditions such as schizophrenia, eating disorders, obsessive-compulsive disorders, depression and anxiety.
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    Research Areas: epilepsy, depression, Parkinson's disease, Alzheimer's disease
  • Casey Overby Lab

    Principal Investigator:
    Casey Taylor, Ph.D.
    Medicine

    Research in the Casey Overby Lab focuses on the intersection of public health genomics and biom...edical informatics. We’re currently developing applications to support the translation of genomic research to clinical and population-based health care settings. We’re also working to develop knowledge-based ways to use big data — including electronic health records — to improve population health. view more

    Research Areas: public health, genomics, electronic health records, bioinformatics
  • Cervical Dysplasia Research Lab

    Lab Website

    We are interested in how immune responses occur in the cervix. The focus of our translational ...research is on developing immune therapies for disease caused by human papillomavirus (HPV). HPV infection causes more cancers than any other virus in the world. Cervical cancer is the most common cancer caused by HPV, and although we have known how to screen for it for over half a century, it remains the second most common cause of cancer death in women. Although the preventive vaccines are a public health milestone, they prevent HPV infections, but are not designed to make immune responses to treat HPV. We are testing different strategies to make immune responses that could treat HPV disease. Our dedicated researchers are working to extend the techniques used in HPV vaccine development to the creation of vaccines targeting other cancers with defined tumor antigens. view more

    Research Areas: cervical cancer, HPV, cancer vaccines
  • Cochlear Center for Hearing and Public Health

    Lab Website

    The Cochlear Center for Hearing and Public Health is dedicated to training clinicians, research...ers and public health experts to study and address the impact that hearing loss has on older adults and public health. We aim to make measured local, national and global impacts through a macro level (e.g., public policy legislation), micro level (e.g., programs to deliver hearing care to individuals in a particular community), and everywhere in between (e.g., influential research publications, etc.) to adhere to our center’s overall mission and vision of effectively optimizing the health and function of an aging society and become the premier global resource for ground-breaking research and training on hearing loss and public health. view more

    Research Areas: otolaryngology, public health, audiology, gerontology, hearing loss, societal perspectives
  • Elizabeth Selvin Lab

    Principal Investigator:
    Elizabeth Selvin, Ph.D., M.P.H.
    Medicine

    The Elizabeth Selvin Lab examines the intersection of epidemiology, clinical policy and public ...health policy. One of our key goals is to use the findings of epidemiologic research to inform the screening, diagnosis and treatment of diabetes, cardiovascular disease and kidney disease. Much of our work looks at biomarkers and diagnostics related to diabetes and diabetes complications. Our findings — linking hemoglobin A1c (HbA1c) to diabetic complications and identifying the role of A1c in diabetes diagnosis — have influenced clinical practice guidelines. view more

    Research Areas: epidemiology, biomarkers, kidney diseases, obesity, diabetes, health care policy, cardiovascular diseases
  • Hadi Kharrazi Lab

    Lab Website
    Principal Investigator:
    Hadi Kharrazi, M.D., Ph.D., M.S.
    Medicine

    Research in the Hadi Kharrazi Lab focuses primarily on contextualizing clinical decision suppor...t (CDS) into population health informatics (PHI) to be used at different HIT levels of managed care, including electronic health records (EHRs) and consumer health informatics (CHI) solutions. Our team has modified and regenerated electronic quality measures (eQM) based on PHI-derived CDS to represent a population aspect of the health quality measurements. Through the Center for Population Health IT (CPHIT) at the Bloomberg School of Public Health, we are pursuing PHI research that provides direct population-based CDS to providers, patients and payers. view more

    Research Areas: informatics, electronic health records, quality of care
  • IndoUS Clinical Research

    Lab Website
    Principal Investigator:
    Amita Gupta, M.D., M.H.S.
    Medicine

    Our IndoUS team, based both in Baltimore and in India, specializes in international clinical re...search (cohort studies and clinical trials), public health implementation science and education in infectious diseases, HIV/AIDS, tuberculosis (TB), vaccine preventable illnesses, antimicrobial resistant infections, and more recently COVID. Since 2003, our work has been focused primarily on India, where we are engaged in several Indo-JHU and international research collaborations. We partner with several leading medical and research institutions in India (e.g. BJGMC, DY Patil, Hinduja Hospital, KEM, Bharati Vidyapeeth, NIRT, JIPMER, CMC, Medanta, IISER, YRG, IIT), as well as others in sub-Saharan Africa, US and Brazil. We are actively involved in the following consortia: 1) Indo-US Vaccine Action Program sponsored RePORT India TB research consortium, which is funded by the US National Institutes of Health (NIH) and the government of India, Department of Biotechnology. 2) RePORT International TB Research Consortium, a multilateral global consortia for TB research, 3) US NIH funded multi-country HIV and TB trials consortia of the AIDS Clinical Trials Group (ACTG) and the International Maternal Pediatric Adolescent AIDS Trials Network (IMPAACT) Network, 4) NIH and AmFAR funded IeDea HIV/TB Working Group and the Treat Asia-IeDEA HIV and TB epidemiology databases, and 5) CDC SHEPHERD AMR studies.

    Our group has been awarded research grants from the US NIH, US CDC, UNITAID, Indian government, and several philanthropic foundations to investigate infectious diseases of importance to India and beyond.
    view more

    Research Areas: international health, infectious disease, antimicrobial resistance, HIV, COVID in adults including pregnant women and children, tuberculosis
  • Larry Chang Lab

    Principal Investigator:
    Larry Chang, M.D., M.P.H.
    Medicine

    Research in the Larry Chang Lab focuses on innovative, multidisciplinary and pragmatic approach...es to impacting the HIV/AIDS pandemic. Our research investigates ways to improve HIV/AIDS care in low- and middle-income settings through strategies that include quantitative methods, qualitative methods, community-based trial designs, and behavioral science and economic evaluations. In addition, we research mobile technologies for health (mHealth) strategies for improving global public health and clinical care, including novel applications for intimate-partner violence intervention, dengue surveillance, and HIV care, surveillance and prevention. view more

    Research Areas: global health, infectious disease, AIDS, HIV, mHealth
  • Maternal-Fetal Medicine Research

    Lab Website

    The Division of Maternal-Fetal Medicine is engaged in clinical, basic bench and epidemiological... research as one of its primary missions. Our strength lies in the expertise and diverse interests of our faculty, as well as in the collaborations with multiple other disciplines and departments throughout the School of Medicine, The Bloomberg School of Public Health, and the School of Biomedical Engineering. The strong research infrastructure of the Johns Hopkins University forms a solid foundation for the success of our integrated research program for Maternal-Fetal Medicine. view more

    Research Areas: maternal health, fetal medicine
  • Mohamed Atta Lab

    Dr. Atta and his research team explore the epidemiological and clinical interventions of a vari...ety of kidney diseases. Our goal is not only to advance the understanding of many kidney diseases but also to capitalize on novel discoveries of basic science to treat a wide range of rare and common kidney disorders.




    • Multi-international observational study of a rare form of amyloid (LECT2 amyloid) to understand its natural history with the ultimate interest of treating this condition.

    • Our group has launched a project investigating the impact of COVID19 on the kidney to identify risk factors influencing outcome across different clinical phenotypes

    • In collaboration with the Division of Infectious Diseases and the School of Public Health, our research has focused on the epidemiology of HIV and kidney disease. We also study clinical markers and contributing factors in the progression of kidney disease, and the association between kidney disease and heart disease.

    • Our research group is participating in a multicenter consortium serving as a clinical core site to study the pathogenesis of HIV-associated kidney disease by providing well-characterized clinical specimens and corresponding clinical and laboratory data.

    view more

    Research Areas: kidney diseases, HIV, hepatitis C
  • Nadia Hansel Lab

    Principal Investigator:
    Nadia Hansel, M.D., M.P.H.
    Medicine

    Research in the Nadia Hansel Lab investigates the clinical, pathophysiologic and public health ...aspects of pulmonary diseases, with a focus on asthma and chronic obstructive pulmonary disease (COPD). We have explored how environmental exposures, nutrition and diet, comorbidity and other factors influence the outcomes of diseases such as asthma and COPD. view more

    Research Areas: airway diseases, immunology, asthma, allergies, lung disease, COPD
  • Richard Chaisson Lab

    Principal Investigator:
    Richard Chaisson, M.D.
    Medicine

    Research in the Richard Chaisson Lab primarily examines tuberculosis and HIV infection, with sp...ecific focus on global epidemiology, clinical trials, diagnostics and public health interventions. Our recent research has involved evaluating a molecular diagnostic test for tuberculosis in HIV patients; observing TB responses during treatment of pulmonary tuberculosis; and examining antiretroviral therapy adherence, virologic and immunologic outcomes in adolescents compared with adults in Southern Africa. view more

    Research Areas: global health, epidemiology, infectious disease, AIDS, HIV, tuberculosis
  • The Ramanathan Lab

    Chronic rhinosinusitis (CRS) is a leading cause of morbidity globally and is the single most co...mmon self-reported chronic health condition and accounts for billions of dollars in health care costs and lost work days annually. Exposure to air pollutants is thought to be a critical modifier of CRS susceptibility. Despite marked reductions in air pollution levels in the United States, the fine particulate component of air pollution (PM2.5) and ultrafine pollutants secondary to traffic continue to remain a recalcitrant issue globally and in the United States. The Ramanathan Lab focuses on studying the role of air pollution (PM2.5) in CRS. In collaboration with scientists at the Bloomberg School of Public Health, we have utilized a state of the art air pollution exposure system to develop a novel mouse model of air pollution induced rhinosinusitis that mimics many of the features of CRS in humans. Our lab uses transgenic mouse models and novel immunologic/genomic techniques to study the mechanisms by which PM2.5 causes eosinophilic inflammation and sinonasal epithelial barrier dysfunction. We are also interested in the role of the antioxidant transcription factor, Nrf2, which has shown to stabilize the epithelial barrier and reduce eosinophilia in PM induced rhinosinusitis as a potential therapeutic target. view more

    Research Areas: nasal polyps, Nrf2, sinonasal epithelial barrier function, particulate matter, chronic rhinosinusitis, epithelial damage, Air pollution
  • Wu Lab

    Principal Investigator:
    Katherine Wu, M.D.
    Medicine

    Dr. Wu leads a multi-disciplinary team with collaborators from the Bloomberg School of Public H...ealth, JHU Whiting School of Engineering, and JHU Krieger School of Arts and Sciences. She conducts ongoing investigations with the Multicenter AIDS Cohort Study and Women’s Inter-agency Health Study. Her lab’s goals are to develop, implement, and validate novel imaging-based metrics of cardiac structure and function to improve risk prediction and stratification at the individual patient-level.

    Research Focuses:

    Predictors of Sudden Cardiac Death by Magnetic Resonance Imaging
    Subclinical myocardial disease in people living with HIV
    Individualized risk prediction
    Cardiac structural and mechanical modeling
    view more

    Research Areas: AIDS, HIV, risk prediction, myocardial disease
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