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• Alison Moliterno Lab

  The Alison Moliterno Lab studies the molecular pathogenesis of myeloproliferative disorders (MPDs), including polycythemia vera, essential thrombocytosis and idiopathic myelofibrosis. Our research is focused on the genetic and epigenetic lesions associated with MPDs, with the goal of improving diagnosis and treatment for these disorders.

  Research Areas: blood disorders, idiopathic myelofibrosis, essential thrombocytosis, epigenetics, genomics, polycythemia vera, myeloproliferative disorders

  

  Principal Investigator

  Alison Moliterno, M.D.

  Department

  Medicine
  

• Jerry Spivak Lab

  Research in the Jerry Spivak Lab focuses on chronic myeloproliferative disorders, particularly their molecular mechanisms and methods for distinguishing them diagnostically and interventionally. By analyzing gene expression in polycythemia vera stem cells, we have learned that patients with polycythemia vera can be differentiated from those with erythrocytosis and can be diagnosed as having either aggressive or slow-growing disease. We are also studying the roles played by specific molecular markers in the pathogenesis and diagnosis of polycythemia vera.

  Research Areas: stem cells, pathogenesis, polycythemia vera, myeloproliferative disorders

  

  Principal Investigator

  Jerry Spivak, M.D.

  Department

  Medicine
  

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