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Research Lab Results for physiology

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  • Pluznick Lab

    Lab Website
    Principal Investigator:
    Jennifer Pluznick, Ph.D.
    Physiology

    The Pluznick Lab is interested in the role that chemosensation plays in regulating physiologica...l processes, particularly in the kidney and the cardiovascular system. We have found that sensory receptors (olfactory receptors, taste receptors, and other G-protein coupled receptors) are expressed in the kidney and in blood vessels, and that individual receptors play functional roles in whole-animal physiology. We are currently working to identify the full complement of sensory receptors found in the kidney, and are working to understand the role that each receptor plays in whole-animal physiology by using a variety of in vitro (receptor localization, ligand screening) and in vivo (whole-animal physiology) techniques. view more

    Research Areas: sensory receptors, cardiovascular, physiology, chemosensation, renal
  • Robert H. Brown Lab

    Lab Website

    Work in the Robert H. Brown Lab explores several topics within pulmonary physiology, with a lon...g-term goal of understanding the structural changes in the lungs that lead to the pathophysiology of lung disease. Our core studies examine the structure-function relationship of pulmonary airways and vessels as well as their role in chronic obstructive pulmonary disease (COPD) and reactive airway disease. Recent research has involved studying the mechanisms and treatment of COPD progression, new methods for treating asthma, and lung inflation and airway hyperresponsiveness. We are also exploring the impact of HIV infection on the etiology of lung disease and the pathophysiologic consequences of lung distention. view more

    Research Areas: asthma, HIV, pulmonary physiology, lung disease, COPD, reactive airway disease
  • Ronald Schnaar Lab

    The Ronald Schnaar Lab is involved in the rapidly expanding field of glycobiology, which studie...s cell surface glycans, lectins, and their roles in cell physiology.

    Current projects in our lab study include (1) Glycans and glycan-binding proteins in inflammatory lung diseases, (2) Ganglioside function in the brain, and (3) HIV-Tat and HIV-associated neurocognitive disorders.
    view more

    Research Areas: cell physiology, HIV, neurocognitive disorders, glycobiology
  • Sensorimotor Adaptation - Vestibular and Oculomotor

    Research in the Sensorimotor Adaptation--Vestibular and Oculomotor group focuses on sensorimoto...r adaptation to space flight and fractal statistics in physiology. Our projects aim to understand sensory processing for motor control with an emphasis on adaptive capabilities and mathematical modeling. view more

    Research Areas: sensorimotor adaptation, physiology, space flight, fractal statistics
  • Sleep Apnea Pathogenesis

    Lab Website
    Principal Investigator:
    Vsevolod Polotsky, M.D., Ph.D.
    Medicine

    Our research laboratory is staffed by a dedicated and experienced team of sleep scientists, fel...lows, technicians, engineers, and students. Currently, we are focused on the following areas:

    -Novel treatments for sleep apnea using electrical and nerve stimulation and chemogenetic techniques

    -Cardiovascular and metabolic effects of sleep apnea and hypoxia

    -Leptin and its impact on breathing and cardiovascular physiology

    -Sleep disordered breathing at high altitude

    -Dietary impacts on asthma
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    Research Areas: hypoxia, sleep apnea
  • Swallowing Investigation in Physiology (SIP) Lab

    Lab Website

    The SIP Lab studies the mechanisms of normal and disordered swallowing. The team conducts resea...rch in the areas of swallowing rehabilitation after stroke, effects of aging on swallowing and measurement of swallowing physiology. view more

    Research Areas: deglutition, swallowing disorders, dysphagia, neurophysiology, stroke, aging, 320-row area detector, MRI, swallowing, physiology, videofluoroscopy, rehabilitation
  • Welling Laboratory

    Lab Website
    Principal Investigator:
    Paul Welling, M.D.
    Medicine

    Dr. Paul A. Welling and his research team explore the genetic and molecular underpinnings of el...ectrolyte physiology, potassium balance disorders, hypertension and kidney disease. A major thrust of current research activity is devoted to understanding how faulty genes and environmental stresses drive hypertension. The research is providing new insights into how the Western diet triggers deleterious responses of salt-sensitivity genes. The Welling laboratory employs a multidisciplinary approach, spanning from gene discovery, molecular biology, genetically engineered mouse models to translational studies in humans. By illuminating pathophysiological mechanisms and translating the discoveries to develop more effective diagnostic and therapeutic strategies, Welling’s group is striving to improve the health of at-risk individuals and patients with kidney disease and hypertension.



    Dr. Welling is the Joseph S. and Esther Hander Professor of Laboratory Research in Nephrology. He has been continuously funded by the National Institutes of Health for over 25 years. Currently he serves as Coordinator of a Global Research Network, funded by the LeDucq Foundation. More about his research can be found at https://www.wellinglab.com/
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    Research Areas: genetic and molecular underpinnings of electrolyte physiology, kidney diseases, hypertension, potassium balance disorders
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