The Mitzner Laboratory studies the physiologic and pathologic basis of lung health and diseases such as emphysema and asthma. We are currently researching why chronic changes in the lung remain for long periods after initial insults have disappeared. Using phenotyping in whole animal models alongside the assessment of the immunologic status of cells and interactive signaling, we examine lung-tissue damage that creates a chronic immunologic response.
The Phenotyping Core promotes functional genomics and other preclinical translational science at Johns Hopkins. We assist and collaborate in the characterization and use of genetically and phenotypically relevant animal models of disease and gene function.