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Displaying 11 to 14 of 14 results for pathology

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  • Richard W. TeLinde Endowed Gynecologic Pathology Lab

    Our scientists pursue out-of-the-box approaches at the very edge of knowledge to:
    1) Elucidate the molecular/cellular/physiological landscapes of ovarian and uterine cancers.
    2) Understand the earliest events in their development and mechanisms of tumor evolution/dormancy and drug resistance.
    3) Deliver promises for better prevention, detection and treatment to women who have diseases or are at an increased risk to have these cancers.

    Research Areas: uterine cancer, gestational trophoblastic disease, ovarian cancer

  • Schneck Lab

    Effective immune responses are critical for control of a variety of infectious disease including bacterial, viral and protozoan infections as well as in protection from development of tumors. Central to the development of an effective immune response is the T lymphocyte which, as part of the adaptive immune system, is central in achieving sterilization and long lasting immunity. While the normal immune responses is tightly regulated there are also notable defects leading to pathologic diseases. Inactivity of tumor antigen-specific T cells, either by suppression or passive ignorance allows tumors to grow and eventually actively suppress the immune response. Conversely, hyperactivation of antigen-specific T cells to self antigens is the underlying basis for many autoimmune diseases including: multiple sclerosis; arthritis; and diabetes. Secondary to their central role in a wide variety of physiologic and pathophysiologic responses my lab takes a broad-based approach to studying T cell re...sponses. view more

    Research Areas: t-cell responses, pathologic diseases, autoimmune diseases, pathology, immune system

    Lab Website

    Principal Investigator

    Jonathan Schneck, M.D., Ph.D.

    Department

    Pathology

  • The Sfanos Lab

    The Sfanos Lab studies the cellular and molecular pathology of prostate disease at the Johns Hopkins University School of Medicine. We are specifically interested in agents that may lead to chronic inflammation in the prostate, such as bacterial infections and prostatic concretions called corpora amylacea. Our ongoing studies are aimed at understanding the influence of prostate infections and inflammation on prostate disease including prostate cancer and benign prostatic hyperplasia (BPH). The laboratory also focuses on the influence of the microbiome on prostate disease development, progression, and/or resistance to therapy.

    Research Areas: disease resistance, prostate cancer, prostate, benign prostatic hyperplasia, prostate disease, chronic inflammation

    Lab Website

    Principal Investigator

    Karen Sfanos, M.S., Ph.D.

    Department

    Pathology

  • Weiss Lab

    The Weiss Lab, which features a multi-disciplinary team at Johns Hopkins as well as at Cedars Sinai Medical Center in Los Angeles, is dedicated to identifying the most important clinical, genetic, structural, contractile and metabolic causes of sudden cardiac death as well as the means to reverse the underlying pathology and lower risk.

    Current projects include research into energy metabolism in human heart failure and creatine kinase metabolism in animal models of heart failure.

    Robert G. Weiss, MD, is professor of medicine, Radiology and Radiological Science, at the Johns Hopkins University.

    Research Areas: energy metabolism, creatine kinase metabolism, imaging, heart failure, aging, cardiology, sudden cardiac death

    Lab Website

    Principal Investigator

    Robert Weiss, M.D.

    Department

    Medicine

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