Research Lab Results for outcomes
Adult Cardiac Catheterization LaboratoryPrincipal Investigator:
Jon Resar, M.D.
Our group is interested in the evaluation of basic pathophysiology in patients undergoing cardi...ac procedures, development and evaluation of new therapeutic strategies, and improving patient selection and outcomes following interventional procedures. view moreResearch Areas: cardiac catheterization, Acute Myocardial Infarction
Alicia Arbaje LabPrincipal Investigator:
Alicia Arbaje, M.D., Ph.D., M.P.H.
Research in the Alicia Arbaje Lab aims to help older adults maintain dignity and quality of lif...e as they age. We are particularly interested in creating health care systems to improve safety and outcomes for older adults. view moreResearch Areas: safety, gerontology, health care systems
Alison E. Turnbull LabLab WebsitePrincipal Investigator:
Alison Turnbull, D.V.M., Ph.D., M.P.H.
Research in the Alison E. Turnbull Lab focuses on patient-clinician interactions. We study deci...sion-making processes for ICU patients and their families and focus on the long-term outcomes of ICU survivors. Additional research examines ways to improve end-of-life care for patients. view moreResearch Areas: epidemiology, palliative care, medical decision making, ICU
Allan Gelber LabPrincipal Investigator:
Allan Gelber, M.D., Ph.D., M.P.H.
The Allan Gelber Lab conducts research on the clinical epidemiology of rheumatic disorders. Our... recent studies have explored topics that include the predicting factors of prevalent and incident gout; cardiovascular disease burden and risk in patients with rheumatoid arthritis; autoantibodies in both primary and secondary SjogrenÕs syndrome; and predictors of outcomes in patients with scleroderma. In addition, we have a long-standing interest in the ways in which racial differences affect disease manifestations in relation to rheumatic disorders. view moreResearch Areas: rheumatology, gout, Sjogren's syndrome, scleroderma, race, health disparities, rheumatoid arthritis
Ana-Marie Orbai LabLab WebsitePrincipal Investigator:
Ana-Maria Orbai, M.D., M.H.S.
The Ana-Marie Orbai Lab focuses on inflammatory arthritis. Current clinical research projects i...n the lab examine patient symptoms and experiences in rheumatic diseases and inflammatory arthritis. We focus on stiffness in rheumatoid arthritis and patient-reported outcomes. Previous research in the lab focused on systemic lupus erythemaous (SLE). view moreResearch Areas: autoimmune rheumatic diseases, arthritis, rheumatoid arthritis
Ari Cedars LaboratoryPrincipal Investigator:
Ari Cedars, M.D.
Ari Cedars, M.D., and his team have three primary research goals. First, the Cedars Lab is inte...rested in patient-centered outcomes in congenital heart disease, which they investigate using a digital tracking system to record participants’ symptoms and quality of life. Second, the Cedars Lab investigates outcomes with mechanical circulatory support and transplant in congenital heart disease, with a focus on those with end-stage heart disease and a Fontan circulation. Third, the Cedars Lab is interested in the biological mechanisms underlying circulatory deterioration and end-organ dysfunction in patients with a Fontan circulation. view moreResearch Areas: heart disease, congenital heart disease
Biophotonics Imaging Technologies (BIT) LaboratoryLab WebsitePrincipal Investigator:
Xingde Li, Ph.D.
Research in the Biophotonics Imaging Technologies (BIT) Laboratory focuses on developing optica...l imaging and nano-biophotonics technology to reduce the random sampling errors in clinical diagnosis, improve early disease detection and guidance of biopsy and interventions, and improve targeted therapy and monitoring treatment outcomes. The imaging technologies feature nondestructiveness, unique functional and molecular specificity, and multi-scale resolution (from organ, to architectural morphology, cellular, subcellular and molecular level). The nano-biophotonics technologies emphasize heavily on biocompatibility, multi-function integration and fast track clinical translation. These imaging and nano-biophotonics technologies can also be potentially powerful tools for basic research such as for drug screening, nondestructive assessment of engineered biomaterials in vitro and in vivo, and for studying brain functions on awake animals under normal or controlled social conditions. view moreResearch Areas: drug screening, imaging, brain, nano-biophotonics
Bradford Winters LabPrincipal Investigator:
Bradford Winters, M.D., Ph.D.
Anesthesiology and Critical Care Medicine
The Bradford Winters Lab conducts research on patient safety and quality of care. Our team focu...ses on the topics of patient care in the intensive care unit, evidence-based medicine, quality health care, and the measurement and evaluation of safety efforts. Currently our work involves evaluating pain management techniques in post-craniotomy patients, developing guidelines for policy development of patient safety initiatives and creating measures for rapid-response system outcomes. view moreResearch Areas: patient safety, ICU, evidence-based medicine, quality of care
Brain Tumor LaboratoryLab WebsitePrincipal Investigator:
Henry Brem, M.D.
At the brain tumor laboratory, Henry Brem, M.D. and Betty Tyler, along with more than 350 train...ees, have conducted scientific research, contributed to scientific literature, amended clinical practice, and illuminated new pathways for improving clinical outcomes.Research Areas: brain tumor drug delivery, brain tumor
The laboratory has advanced the understanding of gene therapy, angiogenesis, intracranial implantation of biodegradable polymers to treat malignant glioma, tumor genetics and proteomics, microchip drug delivery and drug resistance studies. Dr. Brem and his colleagues have designed and led many multi-institutional clinical trials to improve and expand the range of therapeutic options for patients with brain tumors. view more
Cardiac Surgery Research LabLab WebsitePrincipal Investigator:
Jennifer Lawton, M.D.
Founded in 1942 by surgeon Alfred Blalock and surgical technician Vivien Thomas, the Cardiac Su...rgery Research Lab at The Johns Hopkins Hospital serves not only to spearhead discovery and innovation in cardiothoracic surgery, but also to train future leaders in the field. Active areas of investigation include the development of novel, nanoparticle-based therapeutics to mitigate acute lung injury, avoid neurological injury during cardiac surgery, and improve organ preservation during heart and lung transplantation. The lab is also active in a variety of clinical research projects aimed at improving outcomes for our patients.Research Areas: cardiac surgery, nanotechnology, cardiothoracic surgery, surgical models, heart transplant, lung transplant
Equally important, the lab plays a critical role in training residents for impactful careers in academic cardiothoracic surgery. Medical students, residents, and fellows receive hands-on simulation experiences to hone surgical skills outside of the operating room. The lab also serves as a training ground to develop research and investigation skills as trainees learn methods of advanced statistical analysis and academic writing. Special programs for undergraduates and medical students help develop their passion for cardiac surgery and surgical research, giving unique opportunities to young talent. view more