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  • Adult Cardiac Catheterization Laboratory

    Principal Investigator:
    Jon Resar, M.D.
    Medicine

    Our group is interested in the evaluation of basic pathophysiology in patients undergoing cardi...ac procedures, development and evaluation of new therapeutic strategies, and improving patient selection and outcomes following interventional procedures. view more

    Research Areas: cardiac catheterization, Acute Myocardial Infarction
  • Alicia Arbaje Lab

    Research in the Alicia Arbaje Lab aims to help older adults maintain dignity and quality of lif...e as they age. We are particularly interested in creating health care systems to improve safety and outcomes for older adults. view more

    Research Areas: safety, gerontology, health care systems
  • Alison E. Turnbull Lab

    Lab Website

    Research in the Alison E. Turnbull Lab focuses on patient-clinician interactions. We study deci...sion-making processes for ICU patients and their families and focus on the long-term outcomes of ICU survivors. Additional research examines ways to improve end-of-life care for patients. view more

    Research Areas: epidemiology, palliative care, medical decision making, ICU
  • Allan Gelber Lab

    The Allan Gelber Lab conducts research on the clinical epidemiology of rheumatic disorders. Our... recent studies have explored topics that include the predicting factors of prevalent and incident gout; cardiovascular disease burden and risk in patients with rheumatoid arthritis; autoantibodies in both primary and secondary SjogrenÕs syndrome; and predictors of outcomes in patients with scleroderma. In addition, we have a long-standing interest in the ways in which racial differences affect disease manifestations in relation to rheumatic disorders. view more

    Research Areas: rheumatology, gout, Sjogren's syndrome, scleroderma, race, health disparities, rheumatoid arthritis
  • Ana-Marie Orbai Lab

    Lab Website
    Principal Investigator:
    Ana-Maria Orbai, M.D., M.H.S.
    Medicine

    The Ana-Marie Orbai Lab focuses on inflammatory arthritis. Current clinical research projects i...n the lab examine patient symptoms and experiences in rheumatic diseases and inflammatory arthritis. We focus on stiffness in rheumatoid arthritis and patient-reported outcomes. Previous research in the lab focused on systemic lupus erythemaous (SLE). view more

    Research Areas: autoimmune rheumatic diseases, arthritis, rheumatoid arthritis
  • Ari Cedars Laboratory

    Principal Investigator:
    Ari Cedars, M.D.
    Medicine

    Ari Cedars, M.D., and his team have three primary research goals. First, the Cedars Lab is inte...rested in patient-centered outcomes in congenital heart disease, which they investigate using a digital tracking system to record participants’ symptoms and quality of life. Second, the Cedars Lab investigates outcomes with mechanical circulatory support and transplant in congenital heart disease, with a focus on those with end-stage heart disease and a Fontan circulation. Third, the Cedars Lab is interested in the biological mechanisms underlying circulatory deterioration and end-organ dysfunction in patients with a Fontan circulation. view more

    Research Areas: heart disease, congenital heart disease
  • Ashikaga Lab

    Lab Website

    We specialize in unconventional, multi-disciplinary approaches to studying the heart at the int...ersection of applied mathematics, physics and computer science. We focus on theory development that leads to new technology and value delivery to the society. Currently we have three research programs:

    1. Precision Medicine
    To develop a quantitative approach to personalized risk assessment for stroke and dementia based on patent-specific heart anatomy, function and blood flow.
    Disciplines: Cardiac Hemodynamics; Medical Imaging Physics; Continuum Mechanics; Computational Fluid Dynamics

    2. Information Theory
    To quantify and perturb cardiac fibrillation that emerges as a macro-scale behavior of the heart from micro-scale behaviors of inter-dependent components.
    Disciplines: Cardiac Electrophysiology; Spiral Wave; Information Theory; Complex Networks

    3. Artificial Intelligence
    To develop artificial intelligence algorithms to predict the future risk of heart attack, stroke and sudden death, and to assist surgical interventions to prevent these outcomes.
    Disciplines: Medical Imaging Physics; Artificial Intelligence; Robotically Assisted Interventions
    view more

    Research Areas: complex systems, Computational Fluid Dynamics, spiral wave, artificial intelligence, informational theory
  • Biophotonics Imaging Technologies (BIT) Laboratory

    Lab Website
    Principal Investigator:
    Xingde Li, Ph.D.
    Biomedical Engineering

    Research in the Biophotonics Imaging Technologies (BIT) Laboratory focuses on developing optica...l imaging and nano-biophotonics technology to reduce the random sampling errors in clinical diagnosis, improve early disease detection and guidance of biopsy and interventions, and improve targeted therapy and monitoring treatment outcomes. The imaging technologies feature nondestructiveness, unique functional and molecular specificity, and multi-scale resolution (from organ, to architectural morphology, cellular, subcellular and molecular level). The nano-biophotonics technologies emphasize heavily on biocompatibility, multi-function integration and fast track clinical translation. These imaging and nano-biophotonics technologies can also be potentially powerful tools for basic research such as for drug screening, nondestructive assessment of engineered biomaterials in vitro and in vivo, and for studying brain functions on awake animals under normal or controlled social conditions. view more

    Research Areas: drug screening, imaging, brain, nano-biophotonics
  • Bradford Winters Lab

    The Bradford Winters Lab conducts research on patient safety and quality of care. Our team focu...ses on the topics of patient care in the intensive care unit, evidence-based medicine, quality health care, and the measurement and evaluation of safety efforts. Currently our work involves evaluating pain management techniques in post-craniotomy patients, developing guidelines for policy development of patient safety initiatives and creating measures for rapid-response system outcomes. view more

    Research Areas: patient safety, ICU, evidence-based medicine, quality of care
  • Brain Tumor Laboratory

    Lab Website
    Principal Investigator:
    Henry Brem, M.D.
    Neurology
    Neurosurgery

    At the brain tumor laboratory, Henry Brem, M.D. and Betty Tyler, along with more than 350 train...ees, have conducted scientific research, contributed to scientific literature, amended clinical practice, and illuminated new pathways for improving clinical outcomes.



    The laboratory has advanced the understanding of gene therapy, angiogenesis, intracranial implantation of biodegradable polymers to treat malignant glioma, tumor genetics and proteomics, microchip drug delivery and drug resistance studies. Dr. Brem and his colleagues have designed and led many multi-institutional clinical trials to improve and expand the range of therapeutic options for patients with brain tumors.
    view more

    Research Areas: brain tumor drug delivery, brain tumor
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