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Research Lab Results for nerve stimulation

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  • Machine Biointerface Lab

    Lab Website

    Dr. Fridman's research group invents and develops bioelectronics for Neuroengineering and Medical Instrumentation applications. We develop innovative medical technology and we also conduct the necessary biological studies to understand how the technology could be effective and safe for people.

    Our lab is currently focused on developing the "Safe Direct Current Stimulation" technology, or SDCS. Unlike the currently available commercial neural prosthetic devices, such as cochlear implants, pacemakers, or Parkinson's deep brain stimulators that can only excite neurons, SDCS can excite, inhibit, and even sensitize them to input. This new technology opens a door to a wide range of applications that we are currently exploring along with device development: e.g. peripheral nerve stimulation for suppressing neuropathic pain, vestibular nerve stimulation to correct balance disorders, vagal nerve stimulation to suppress an asthma attack, and a host of other neuroprosthetic applications.

    M...edical Instrumentation MouthLab is a "tricorder" device that we invented here in the Machine Biointerface Lab. The device currently obtains all vital signs within 60s: Pulse rate, breathing rate, temperature, blood pressure, blood oxygen saturation, electrocardiogram, and FEV1 (lung function) measurement. Because the device is in the mouth, it has access to saliva and to breath and we are focused now on expanding its capability to obtaining measures of dehydration and biomarkers that could be indicative of a wide range of internal disorders ranging from stress to kidney failure and even lung cancer.
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    Research Areas: medical instruments, bioelectricities, neuroengineering, nerve stimulation
  • Sleep Apnea Pathogenesis

    Lab Website
    Principal Investigator:
    Vsevolod Polotsky, M.D., Ph.D.
    Medicine

    Our research laboratory is staffed by a dedicated and experienced team of sleep scientists, fellows, technicians, engineers, and students. Currently, we are focused on the following areas:

    -Novel treatments for sleep apnea using electrical and nerve stimulation and chemogenetic techniques

    -Cardiovascular and metabolic effects of sleep apnea and hypoxia

    -Leptin and its impact on breathing and cardiovascular physiology

    -Sleep disordered breathing at high altitude

    -Dietary impacts on asthma

    Research Areas: hypoxia, sleep apnea
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