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Displaying 1 to 3 of 3 results for myositis

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  • Antony Rosen Lab

    Research in the Antony Rosen Lab investigates the mechanisms shared by the autoimmune rheumatic diseases such as lupus, myositis, rheumatoid arthritis, scleroderma and SjogrenÕs syndrome. We focus on the fate of autoantigens in target cells during various circumstances, such as viral infection, relevant immune effector pathways and exposure to ultraviolet radiation. Our recent research has sought to define the traits of autoantibodies that enable them to induce cellular or molecular dysfunction. We also work to better understand the mechanisms that form the striking connections between autoimmunity and cancer.

    Research Areas: myositis, lupus, rheumatology, Sjogren's syndrome, scleroderma, autoimmune rheumatic diseases, rheumatoid arthritis

    Principal Investigator

    Antony Rosen, M.B.Ch.B., M.S.

    Department

    Medicine

  • Livia Casciola-Rosen Lab

    Work in the Livia Casciola-Rosen Lab explores the shared mechanisms present in autoimmune rheumatic diseases, specifically scleroderma, Sjogren's syndrome and myositis. We use disease-specific autoantibodies to identify the factors that cause the autoimmune response in such diseases. Our current research involves identifying the antigen targets of autoimmune diseases, investigating the autoantigens targeted in cancers associated with rheumatic diseases and finding unique clinical biomarkers, such as the anti-HMGCR antibody specificity.

    Research Areas: autoantibodies, myositis, rheumatology, Sjogren's syndrome, scleroderma, autoimmune rheumatic diseases

    Principal Investigator

    Livia Casciola-Rosen, Ph.D.

    Department

    Medicine

  • Sonye Danoff Lab

    Research in the Sonye Danoff Lab includes both basic and translational studies of lung fibrosis. We have explored topics such as the role of support measures and palliative care, pulmonary manifestations of Sjogren's syndrome, idiopathic inflammatory myopathies and the treatment of cough in idiopathic pulmonary fibrosis. Our research has also involved investigating the lung as a potential target for the immune reaction in myositis.

    Research Areas: myositis, interstitial lung diseases, Sjogren's syndrome, lung disease, pulmonary fibrosis, autoimmune diseases

    Principal Investigator

    Sonye Danoff, M.D., Ph.D.

    Department

    Medicine

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