Research Lab Results for myeloproliferative disorders
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Alison Moliterno Lab
The Alison Moliterno Lab studies the molecular pathogenesis of myeloproliferative disorders (MP...Ds), including polycythemia vera, essential thrombocytosis and idiopathic myelofibrosis. Our research is focused on the genetic and epigenetic lesions associated with MPDs, with the goal of improving diagnosis and treatment for these disorders. view more
Research Areas: blood disorders, idiopathic myelofibrosis, essential thrombocytosis, epigenetics, genomics, polycythemia vera, myeloproliferative disorders -
Jerry Spivak Lab
Research in the Jerry Spivak Lab focuses on chronic myeloproliferative disorders, particularly ...their molecular mechanisms and methods for distinguishing them diagnostically and interventionally. By analyzing gene expression in polycythemia vera stem cells, we have learned that patients with polycythemia vera can be differentiated from those with erythrocytosis and can be diagnosed as having either aggressive or slow-growing disease. We are also studying the roles played by specific molecular markers in the pathogenesis and diagnosis of polycythemia vera. view more
Research Areas: stem cells, pathogenesis, polycythemia vera, myeloproliferative disorders
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