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Research Lab Results for motor learning

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  • David Linden Lab

    Principal Investigator:
    David Linden, Ph.D.
    Neuroscience

    The David Linden Laboratory has used both electrode and optical recording in cerebellar slice and culture model systems to explore the molecular requirements for induction and expression of these phenomena. Along the way, we discovered a new form of plasticity. In addition, we have expanded our analysis to include use-dependent synaptic and non-synaptic plasticity in the cerebellar output structure, the deep nuclei.

    Our investigations are central to understanding the cellular substrates of information storage in a brain area where the behavioral relevance of the inputs and outputs is unusually well defined. In addition, our investigations have potential clinical relevance for cerebellar motor disorders and for disorders of learning and memory generally.

    Research Areas: motor learning, synaptic plasticity, neurobiology, memory, cerebellum, brain
  • Human Brain Physiology and Stimulation Lab

    Lab Website

    The Human Brain Physiology and Stimulation Laboratory studies the mechanisms of motor learning and develops interventions to modulate motor function in humans. The goal is to understand how the central nervous system controls and learns to perform motor actions in healthy individuals and in patients with neurological diseases such as stroke. Using this knowledge, we aim to develop strategies to enhance motor function in neurological patients.

    To accomplish these interests, we use different forms of non-invasive brain stimulation techniques, such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), as well as functional MRI and behavioral tasks.

    Research Areas: motor learning, TMS, brain stimulation, neurologic rehabilitation, tDCS, stroke rehabilitation, stroke recovery
  • Laboratory of Vestibular NeuroAdaptation

    The Laboratory of Vestibular NeuroAdaptation investigates mechanisms of gaze stability in people with loss of vestibular sensation. A bulk of our research investigates motor learning in the vestibulo-ocular reflex (VOR) using different types of error signals. In addition, we investigate the synergistic relationship between the vestibular and saccadic oculomotor systems as trainable strategies for gaze stability. We are particularly interested in developing novel technologies to assess and deliver improved rehabilitation outcomes. We are validating a hand-held computer tablet for assessment of sensorimotor function and participating in a clinical trial comparing traditional vestibular rehabilitation against a device developed in our laboratory that can unilaterally or bilaterally strengthen the VOR.

    Members of the lab include physical therapists, physicians, engineers, statisticians and post-doctoral fellows. The laboratory is supported by generous grant funding from NASA, the NIH, ...the DOD and grateful patients
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    Research Areas: gaze stability, vestibular sensation, vestibulo-ocular reflex, rehabilitation, sensorimotor functions
  • Motion Analysis Laboratory

    Lab Website

    Our team is focused on understanding how complex movements are normally learned and controlled, and how damage to specific brain areas impairs these processes. We employ several techniques to quantify movement including: 3-dimensional tracking and reconstruction of movement, recordings of muscle activity, force plate recordings, and calculation of joint forces and torques. These techniques allow for very precise measurements of many different types of movements including: walking, reaching, leg movements, hand movements and standing balance. All studies are designed to test specific hypotheses about the function of different brain areas, the cause of specific impairments and/or the effects of different interventions.

    Research Areas: cerebellar function, neurological diseases, motor learning
  • Vikram Chib Lab

    Lab Website

    The goals of the Vikram Chib Lab are to understand how the nervous system organizes the control of movement and how incentives motivate our behaviors. To better understand neurobiological control, our researchers are seeking to understand how motivational cues drive our motor actions. We use an interdisciplinary approach that combines robotics with the fields of neuroscience and economics to examine neuroeconomics and decision making, motion and force control, haptics and motor learning, image-guided surgery and soft-tissue mechanics.

    Research Areas: soft-tissue mechanics, robotics, motor learning, neuroeconomics, movement, neurobiological control, neuroscience, image-guided surgery, economics, decision making, nervous system
  • Zanvyl Krieger Mind/Brain Institute

    Lab Website
    Principal Investigator:
    Charles Connor, Ph.D.
    Neuroscience

    The Zanvyl Krieger Mind/Brain Institute is dedicated to the study of the neural mechanisms of higher brain functions using modern neurophysiological, anatomical and computational techniques. Our researchers use various approaches to understand information processing and its influence on perception, memory, abstract thought, complex behavior and consciousness. Systems and cognitive laboratories use neurophysiology, brain imaging and psychophysics to develop a quantitative, network-level understanding of cognitive information processing. Other researchers use analytical approaches such as system identification, dimensionality reduction, information theory and network modeling to understand information processing. Other areas of research in the Institute include the study of how visual and tactile information processing leads to perception and understanding of two- and three-dimensional objects. Another focus is on neural processing and recognition of speech and other complex sounds. St...ill other laboratories study neural mechanisms of attention, memory formation, motor learning, decision-making and executive control of behavior. view more

    Research Areas: brain, neurophysiology, consciousness, neuroscience, perception
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