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Displaying 11 to 18 of 18 results for kidney diseases

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  • Michael Klag Lab

    The Michael Klag Lab focuses on the epidemiology and prevention of kidney disease, cardiovascular disease and hypertension. Our research determined that the U.S. was experiencing an epidemic of end-stage kidney disease, pinpointed the incidence of kidney disease and published scholarship on risk factors for kidney disease such as race, diabetes and socioeconomic status. Our Precursors Study has shown that serum cholesterol measured at age 22 years is a predictor for midlife cardiovascular disease, a finding that has influenced policy about cholesterol screening in young adults. We also research health behaviors that lead to hypertension and study how differences in these behaviors affect urban and non-urban populations.

    Research Areas: longitudinal data, kidney diseases, health behaviors, hypertension, cardiovascular diseases, cholesterol

    Principal Investigator

    Michael Klag, M.D., M.P.H.

    Department

    Medicine

  • Mohamed Atta Lab

    Dr. Atta and his research team explore the epidemiological and clinical interventions of a variety of kidney diseases. Our goal is not only to advance the understanding of many kidney diseases but also to capitalize on novel discoveries of basic science to treat a wide range of rare and common kidney disorders.




    • Multi-international observational study of a rare form of amyloid (LECT2 amyloid) to understand its natural history with the ultimate interest of treating this condition.

    • Our group has launched a project investigating the impact of COVID19 on the kidney to identify risk factors influencing outcome across different clinical phenotypes

    • In collaboration with the Division of Infectious Diseases and the School of Public Health, our research has focused on the epidemiology of HIV and kidney disease. We also study clinical markers and contributing factors in the progression of kidney disease, and the association between kidney disease and h...eart disease.

    • Our research group is participating in a multicenter consortium serving as a clinical core site to study the pathogenesis of HIV-associated kidney disease by providing well-characterized clinical specimens and corresponding clinical and laboratory data.

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    Research Areas: kidney diseases, HIV, hepatitis C

    Principal Investigator

    Mohamed Atta, M.B.B.Ch., M.D., M.P.H.

    Department

    Medicine

  • Rakhi Naik Lab

    The Rakhi Naik Lab studies sickle cell disease. We focus on complications related to the disease, including chronic kidney disease and venous thromboembolism. By defining the risks and factors for diseases related to the sickle cell trait, we hope to improve genetic counseling and screening and treatment recommendations. Other research in the lab examines the epidemiology and unique mechanisms of thrombosis in patients with hemoglobin disorders. Specifically, we are trying to identify mechanisms of hypercoagulability and develop treatments for patients with hemoglobinopathies.

    Research Areas: epidemiology, sickle cell diseases, kidney diseases, venous thromboembolism, hemoglobin disorders, genetic counseling

    Principal Investigator

    Rakhi Naik, M.D., M.H.S.

    Department

    Medicine

  • Raquel Greer Lab

    Work in the Raquel Greer Lab focuses primarily on health disparities in chronic kidney disease. Our most recent research explored the challenges perceived by primary care providers in educating patients about chronic kidney disease as well as physicians’ views on barriers to adequate preparation of patients for renal replacement therapy. We also are interested in examining how clinical-patient communication can impact quality of care in the primary care setting.

    Research Areas: primary care, kidney diseases, patient-provider relationships

    Principal Investigator

    Raquel Greer, M.D., M.H.S.

    Department

    Medicine

  • Sharon Turban Lab

    Research in the Sharon Turban Lab focuses on the effects of sodium and potassium on blood pressure and on kidney function. We lead the Chronic Kidney Disease-Potassium (CKD-K) clinical trial, funded by American Heart Association, which examines the benefits and safety of two levels of potassium intake in patients with kidney disease. Other research includes the Chronic Renal Insufficiency Cohort (CRIC) study, which aims to improve the understanding of chronic kidney disease and related cardiovascular illness.

    Research Areas: sodium, kidney diseases, potassium, chronic kidney disease, blood pressure

    Principal Investigator

    Sharon Turban, M.D.

    Department

    Medicine

  • Stephen Sozio Lab

    Dr. Sozio’s research focuses on 1) Clinical research related to chronic kidney disease and end stage renal disease, and 2) Educational research in undergraduate and graduate medical education.



    The Sozio lab pursues work related to stroke, cognitive impairment, manifestations of kidney disease, and systematic reviews on clinical topics, and collaborates on multiple projects with other key investigators. In particular, Dr. Sozio has been an active investigator in the Choices for Healthy Outcomes in Caring for ESRD (CHOICE) Study, Predictors of Arrhythmic and Cardiovascular Risk in End Stage Renal Disease (PACE) Study, Chronic Renal Insufficiency Cohort (CRIC) Study, and work funded through the Agency for Healthcare Research and Quality (AHRQ) and Johns Hopkins Evidence-Based Practice Center. In addition, the Sozio lab performs studies at the UME and GME levels, investing in understanding learners’ mentorship, research, and transitional experiences.

    Research Areas: end stage renal disease (ESRD), epidemiology, kidney diseases, stroke

    Principal Investigator

    Stephen Sozio, M.D.

    Department

    Medicine

  • Welling Laboratory

    Dr. Paul A. Welling and his research team explore the genetic and molecular underpinnings of electrolyte physiology, potassium balance disorders, hypertension and kidney disease. A major thrust of current research activity is devoted to understanding how faulty genes and environmental stresses drive hypertension. The research is providing new insights into how the Western diet triggers deleterious responses of salt-sensitivity genes. The Welling laboratory employs a multidisciplinary approach, spanning from gene discovery, molecular biology, genetically engineered mouse models to translational studies in humans. By illuminating pathophysiological mechanisms and translating the discoveries to develop more effective diagnostic and therapeutic strategies, Welling’s group is striving to improve the health of at-risk individuals and patients with kidney disease and hypertension.



    Dr. Welling is the Joseph S. and Esther Hander Professor of Laboratory Research in Nephrology. He ...has been continuously funded by the National Institutes of Health for over 25 years. Currently he serves as Coordinator of a Global Research Network, funded by the LeDucq Foundation. More about his research can be found at https://www.wellinglab.com/ view more

    Research Areas: genetic and molecular underpinnings of electrolyte physiology, kidney diseases, hypertension, potassium balance disorders

    Lab Website

    Principal Investigator

    Paul Welling, M.D.

    Department

    Medicine

  • William B. Guggino Lab

    Work in the William B. Guggino Lab focuses on the structure of the cystic fibrosis transmembrane conductance regulator (CFTR) and water channels; the molecular structure of transport proteins in epithelial cell membranes; and gene therapies to treat cystic fibrosis (CF) patients. We are also working to identify CF’s specific defect in chloride channel regulation. One recent study showed that insulin-like growth factor 1 (IGF-1) enhances the protein expression of CFTR.

    Research Areas: cell biology, cystic fibrosis, kidney diseases, gene therapy, ion channels

    Lab Website

    Principal Investigator

    William Guggino, Ph.D.

    Department

    Physiology

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