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Research Lab Results for kidney diseases

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  • Chirag Parikh Lab

    Lab Website
    Principal Investigator:
    Chirag Parikh, M.B.B.S., Ph.D.
    Medicine

    Dr. Parikh's research focuses on the translation and validation of novel biomarkers for the dia...gnosis and prognosis of acute kidney injury. Progress in kidney diseases has been hamstrung by significant heterogeneity within the current disease definitions, which are largely based on serum creatinine. Dr. Parikh's research has addressed this critical challenge by developing biomarkers of renal tubular injury, repair, and inflammation to dissect this heterogeneity. He has assembled multicenter longitudinal prospective cohorts for translational research studies across several clinical settings of acute kidney injury and chronic kidney disease for the efficient translation of novel biomarkers.



    His research is dedicated to the process of applying discoveries generated in the laboratory and in preclinical experiments, the development of clinical studies, and the design of clinical trials. Dr. Parikh's studies have refined the clinical definition in perioperative acute kidney injury and hepatorenal syndrome, developed strategies to reduce kidney discard in deceased donor transplantation, and advanced regulatory approvals of kidney injury biomarkers. He has also developed biomarkers to identify rapid progressors of early diabetic kidney disease before derangements in serum creatinine. Dr. Parikh's research goal is to translate our understanding of pathophysiological mechanisms into clinical practice and improve the outcomes in patients with kidney disease.



    Dr. Parikh has also been the recipient of numerous honors, including the 2017 Young Investigator Award from the American Society of Nephrology.
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    Research Areas: acute kidney injury, biomarkers, Kidney Transplantation, chronic kidney disease
  • Edgar Miller Lab

    Principal Investigator:
    Edgar Miller, M.D., Ph.D.
    Medicine

    Research in the Edgar Miller Lab focuses on nutrition, hypertension and kidney disease. Current... projects include a National Heart, Lung, and Blood Institute study on dietary carbohydrate and glycemic index effects on markers of oxidative stress, inflammation and kidney function; and a National Institute of Diabetes and Digestive and Kidney Diseases randomized controlled trial that examines the effects of omega-3 fatty acid supplementation on urine protein excretion in diabetic kidney disease. view more

    Research Areas: nutrition, kidney diseases, diabetes, inflammation
  • Mark Sulkowski Lab

    Lab Website
    Principal Investigator:
    Mark Sulkowski, M.D.
    Medicine

    Research in the Mark Sulkowski Lab focuses on hepatitis B and hepatitis C. We've conducted clin...ical research related to the management of viral hepatitis, including novel agents. Other studies focus on adult patients at the Johns Hopkins site of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Hepatitis B Clinical Research Network as well as the National Institute of Allergy and Infectious Diseases Adult AIDS Clinical Trials Group. view more

    Research Areas: infectious disease, hepatitis B, hepatitis C
  • Mohamed Atta Lab

    Dr. Atta and his research team explore the epidemiological and clinical interventions of a vari...ety of kidney diseases. Our goal is not only to advance the understanding of many kidney diseases but also to capitalize on novel discoveries of basic science to treat a wide range of rare and common kidney disorders.




    • Multi-international observational study of a rare form of amyloid (LECT2 amyloid) to understand its natural history with the ultimate interest of treating this condition.

    • Our group has launched a project investigating the impact of COVID19 on the kidney to identify risk factors influencing outcome across different clinical phenotypes

    • In collaboration with the Division of Infectious Diseases and the School of Public Health, our research has focused on the epidemiology of HIV and kidney disease. We also study clinical markers and contributing factors in the progression of kidney disease, and the association between kidney disease and heart disease.

    • Our research group is participating in a multicenter consortium serving as a clinical core site to study the pathogenesis of HIV-associated kidney disease by providing well-characterized clinical specimens and corresponding clinical and laboratory data.

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    Research Areas: kidney diseases, HIV, hepatitis C
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