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• Alyssa Parian Lab

  The Alyssa Parian Lab works to identify early markers of dysplasia. We also study inflammatory bowel disease-associated cancers, conduct IBD clinical trials and examine IBD extraintestinal manifestations.

  Research Areas: inflammatory bowel disease, cancer, displaysia

  

  Principal Investigator

  Alyssa Parian, M.D.

  Department

  Medicine
  

• Brindusa Truta Lab

  The Brindusa Truta Lab studies inflammatory bowel diseases, specifically Crohn’s disease and ulcerative colitis. Recent studies defined factors associated with the development of Crohn's disease after ileal pouch anal anastomosis; determined the value of histology in identifying Lynch syndrome in early-onset of colorectal cancer patients; and compared the phenotype and genotype in adenomatous polyposis patients with and without a family history.

  Research Areas: inflammatory bowel disease, Crohn’s disease, ulcerative colitis

  

  Principal Investigator

  Brindusa Truta, M.A.S., M.D.

  Department

  Medicine
  

• Heng Zhu Lab

  The Zhu lab is focused on characterizing the activities of large collection of proteins, building signaling networks for better understanding the mechanisms of biological processes, and identifying biomarkers in human diseases and cancers. More specifically, our group is interested in analyzing protein posttranslational modifications, and identifying important components involved in transcription networks and host-pathogen interactions on the proteomics level, and biomarkers in human IBD diseases.

  Research Areas: inflammatory bowel disease, biomarkers, cancer

  Lab Website

  

  Principal Investigator

  Heng Zhu, Ph.D.

  Department

  Pharmacology and Molecular Sciences
  

• IBD and Autoimmune Liver Diseases Laboratory

  Investigators in the IBD and Autoimmune Liver Diseases Laboratory conduct basic and translational research in inflammatory bowel disease (IBD) and autoimmune liver diseases. One area of focus is discovering and developing biomarkers for diagnosing and prognosticating IBD and other autoimmune liver diseases (AILDs). We also are exploring the molecular pathogenesis of—and developing novel therapies for—IBD. In addition, we are working to understand the molecular reason why many IBD patients fail to respond to mainstay drug therapies—and to develop diagnostic assays that can predict non-responders before starting them on those therapies. These biomarker studies have led to our application for four U.S. and international patents.

  Research Areas: inflammatory bowel disease, Crohn’s disease, gastrointestinal system, colitis, autoimmune diseases, pathogenesis, celiac disease, liver diseases

  Lab Website

  

  Principal Investigator

  Xu Li, Ph.D.

  Department

  Medicine
  

• Joanna Peloquin Lab

  The Joanna Peloquin Lab focuses on inflammatory bowel disease (IBD). We're working on individualized care for IBD patients through functional genomic studies, specifically those related to diet, host and microbiota interactions.

  Research Areas: inflammatory bowel disease, gastroenterology, nutrition, microbiota, genomics

  

  Principal Investigator

  Joanna Melia, M.D.

  Department

  Medicine
  

• Sharon Dudley Brown Lab

  Research in the Sharon Dudley Brown Lab focuses on gastroenterology and hepatology, inflammatory bowel disease and ulcerative colitis.

  Research Areas: inflammatory bowel disease, gastroenterology, hepatology, ulcerative colitis

  

  Principal Investigator

  Sharon Dudley-Brown, Ph.D.

  Department

  Medicine
  

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