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Displaying 1 to 2 of 2 results for herpesvirus

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  • Gary S. Hayward Laboratory

    Research in the Gary S. Hayward Laboratory is related to human herpesvirus. Specifically, researchers are seeking to understand how the different classes of herpes viruses take control of transcription, DNA replication, cell cycle and other nuclear processes of their host cells and how they also block or evade apoptotic and immune responses in both the lytic and latent state.

    Research Areas: immunology, herpesvirus, pathogenesis, transcriptional regulation

    Lab Website

    Principal Investigator

    Gary Hayward, Ph.D.

    Department

    Oncology

  • Richard F. Ambinder Lab

    Epstein-Barr virus and Kaposi's sarcoma herpesvirus are found in association with a variety of cancers. Our laboratory studies are aimed at better defining the role(s) of the virus in the pathogenesis of these diseases and the development of strategies to prevent, diagnose or treat them. We have become particularly interested in the unfolded protein response in activation of latent viral infection. Among the notions that we are exploring is the possibility that activation of virus-encoded enzymes will allow the targeted delivery of radation. In addition, we are investigating a variety of virus-related biomarkers including viral DNA, antibody responses, and cytokine measurements that may be clinically relevant.

    Research Areas: virology, antiviral therapy

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