Show: 10 · 20 · 50

1. 1

• Atul Bedi Lab

  The Atul Bedi Lab in the Head and Neck cancer research program provides fundamental insights into the molecular determinants and mechanisms by which tumor cells evade death signals entrained by the immune system and anticancer agents. Their recent studies show that tumor-induced immune tolerance limits the in vivo anti-tumor efficacy of tumor-targeted antibodies and that the tumor cell-autonomous expression of transforming growth factor-b (TGF-b) is a key molecular determinant of the de novo or acquired resistance of cancers to EGFR-targeted antibody. Their laboratory has developed novel bi-functional antibody-based strategies to simultaneously counteract immune tolerance in the tumor microenvironment and to enhance the anti-tumor efficacy of targeted antibody therapies for the treatment of cancer.

  Research Areas: targeted antibody therapies, transforming growth factor-b, cancer, head and neck cancer, tumor-targeted antibodies

  

  Principal Investigator

  Atul Bedi, M.B.B.S.

  Department

  Otolaryngology - Head and Neck Surgery
  

• Head and Neck Cancer Clinical Trials and Tissue Bank

  The Johns Hopkins Head and Neck Cancer Tissue Bank enrolls patients and collects research specimens from Head and Neck Tumor patients, both cancerous and benign, with particular focus on Head and Neck Squamous Cell Cancer patients. It provides specimens to researchers both within the institution and outside.

  Research Areas: benign, malignant, cancer, tumor, head and neck tumors, Squamous cell carcinoma

  

  Principal Investigator

  Zubair Khan, M.B.B.S., M.P.H.

  Department

  Otolaryngology - Head and Neck Surgery
  

• Mariana Brait Lab

  Description

  Research Areas: Circulating DNA, Salivary Gland Tumors, Translational Cancer Research, genetics, cancer biomarkers, epigenetics, Early Detection of Cancer, head and neck cancer

  

  Principal Investigator

  Mariana Brait, M.Sc., Ph.D.

  Department

  Otolaryngology - Head and Neck Surgery
  

1. 1