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Work in the Ayse Gurses Lab examines several topics related to human factors, including methods for improving patient safety in the cardiac operating room, care coordination, transitions of care and compliance of providers with evidence-based guidelines. Our team also has an interest in research that explores the working conditions of nurses. We collaborate on studies related to the development of geriatrics health service delivery at all levels of the health system.
Principal Investigator
Department
The Bradford Winters Lab conducts research on patient safety and quality of care. Our team focuses on the topics of patient care in the intensive care unit, evidence-based medicine, quality health care, and the measurement and evaluation of safety efforts. Currently our work involves evaluating pain management techniques in post-craniotomy patients, developing guidelines for policy development of patient safety initiatives and creating measures for rapid-response system outcomes.
Principal Investigator
Department
Work in the Christopher Chute Lab involves the management of clinical data to enable effective evidence-based clinical practice and translational research. Recently, we developed an EHR-based genetic testing knowledge base to be integrated into the genetic testing ontology (GTO) and identified potential barriers to pharmacogenomics clinical decision support (CDS) implementation.
Work in the Eric Bass Lab focuses on evidence-based medicine, comparative effectiveness research, and community health partnerships. Our work is closely aligned with the Center for Health Services and Outcomes Research and the Johns Hopkins Evidence-Based Practice Center.
Research in the Felicia Hill-Briggs Lab focuses on assessment methods and clinical intervention in behavioral medicine, with an emphasis on patient self-management and outcomes in ethnic minorities with chronic diseases. We are interested in the application of problem-solving and decision-making models to self-management and health behavior change. Our recent research involves examining problem-solving training for cardiovascular disease risk self-management in African Americans with type 2 diabetes. We also have a long-standing interest in cognitive/neuropsychological processes in chronic diseases, translation of research to clinical practice settings and community-based settings, and evidence-based behavioral medicine.
Researchers in the Harold Lehmann Lab study evidence-based medicine. We are currently examining the informatics infrastructure of research and the secondary use of electronic health record data for research. The team is also evaluating the value of classic evidence reports versus social media versus links to community services for community health workers.
Research in the Jeremy Sugarman Lab focuses on biomedical ethics—particularly, the application of empirical methods and evidence-based standards to the evaluation and analysis of bioethical issues. Our contributions to medical ethics and health policy include work on the ethics of informed consent, umbilical cord blood banking, stem cell research, international HIV prevention research, global health and research oversight.
Research in the Jodi Segal Lab focuses on developing methodologies to use observational data to understand the use of new drugs, particularly drugs for treating diabetes, blood disorders and osteoporosis. We apply advanced methods for evidence-based review and meta-analysis, and—in collaboration with Johns Hopkins biostatisticians—we have developed new methodologies for observational research (using propensity scores to adjust for covariates that change over time) and methods to account for competing risks and heterogeneity of treatment effects in analyses.
The Johns Hopkins Evidence-Based Practice Center conducts comprehensive, systematic reviews of important medical topics using interdisciplinary teams that integrate clinical expertise in evidence-based methods, including meta-analysis, decision analysis, benefit-harms analysis and cost-effectiveness analysis.
Work in the Kelly Gebo Lab focuses on topics such as evidence-based practice, health utilization, policy generation, health disparities in patient access to health care, HIV/AIDS, aging and hepatitis. As part of the HIV Research Network (HIVRN), our lab gathers clinical and demographic data on HIV-infected patients to help develop a single, nationwide research database. In addition, our ongoing research explores evidence-based practice in relation to the management of hepatitis C as well as HIV/AIDS in mentally ill patients. We also investigate racial and gender disparities in patients who receive highly active antiretroviral therapy.
Research in the Laura Gitlin Lab focuses on aging in place, family caregiving, nonpharmacologic approaches to dementia care and functional disability. We study quality-of-life improvements for people with dementia or functional difficulties and their caregivers, including adaptive aids such as assistive devices and environmental modifications. Other research investigates disparities in mental health in older African Americans undergoing treatment for depression.
Research in the Samantha Pitts Lab focuses on care safety and quality in ambulatory patients. Specifically, our activities have included applying the Comprehensive Unit-based Safety Program (CUSP) in office-based practices and improving the delivery of evidence-based care through clinical care teams.
Work in the Sean Berenholtz Lab focuses on patient safety, ICU care, quality health care and evidence-based medicine. Two notable and successful projects include the National On The Cusp: Stop BSI project, which was implemented in 47 states with the goal of eliminating bloodstream infections, and the Agency for Healthcare Research and Quality (AHRQ)-funded Keystone ICU project, which improved communication and teamwork and reduced hospital-acquired infections in more than 100 ICUs in Michigan. One recent study focused on ventilator-associated pneumonia (VAP), one of the most common type of health care-associated infections in the ICU. Existing VAP prevention intervention bundles vary widely on the interventions, but our research team described a structured approach for developing a new VAP prevention bundle.
Work in the Srinivasa Raja Lab seeks to better understand both the peripheral and central mechanisms that cause neuropathic pain, including various methods for treatment. A large focus of our research is on exploring the role of opioid and adrenergic receptor mechanisms in the management of chronic neuropathic pain. Our team also studies the mechanisms of spinal cord stimulation for treating chronic pain, and we have conducted controlled clinical trials in an effort to improve evidence-based practices for pharmacological treatment of neuropathic pain.
The research mission of the Zackary Berger Lab is to bridge evidence-based medicine and shared decision-making in the context of patient-centered care. Lab studies investigate how to accomplish this in the common case of uncertainty, while seeking to clarify the ethics of decision-making and empirically describe how shared decision-making is and should be done.
Zackary Berger, MD, PhD, is an assistant professor in the Division of General Internal Medicine at the Johns Hopkins School of Medicine. In addition to his work as an internist and primary care physician, Dr. Berger is an associate faculty member in the Berman Institute of Bioethics, and core faculty in the Evidence Based Practice Center as well as the Center for Health Services and Outcomes Research.
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