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The Alain Labrique Lab conducts research on infectious diseases and public health. Our team studies the various factors that lead to maternal and neonatal mortality, particularly in underserved populations in South Asia, using the tools of infectious disease epidemiology, molecular biology and biostatistics. We work to better understand factors such as the interface of micronutrient deficiency and maternal/infant mortality and the prevention of nosocomial infections through mechanistic or nutritional interventions. We also have a longstanding interest in technologies that may enable early detection of disease.
Research in the Alison E. Turnbull Lab focuses on patient-clinician interactions. We study decision-making processes for ICU patients and their families and focus on the long-term outcomes of ICU survivors. Additional research examines ways to improve end-of-life care for patients.
The Allan Gelber Lab conducts research on the clinical epidemiology of rheumatic disorders. Our recent studies have explored topics that include the predicting factors of prevalent and incident gout; cardiovascular disease burden and risk in patients with rheumatoid arthritis; autoantibodies in both primary and secondary SjogrenÕs syndrome; and predictors of outcomes in patients with scleroderma. In addition, we have a long-standing interest in the ways in which racial differences affect disease manifestations in relation to rheumatic disorders.
The Anna Durbin Lab evaluates experimental vaccines through human clinical trials. We have conducted both pediatric and adult clinical trials on vaccines for HIV, hepatitis C, HPV, influenza, malaria, dengue virus, rotavirus and other viruses. We also have a longstanding interest in better understanding the immunologic factors of dengue infection and disease. We’re working to identify the viral, host and immunologic factors that cause severe dengue illness.
Research in the Ariel Green Lab focuses on informing and improving decisions surrounding the use of invasive medical technologies for older adults with complex medical diseases. Our long-term goals are to conduct epidemiologic research, create public health initiatives, and help shape policies that improve the lives of older adults.
The Bryan Lau Lab is interested in epidemiological and statistical methods for cohort studies and the application of these methods primarily to HIV cohort studies. We’re particularly interested in developing new methods and using approaches from other disciplines as novel solutions to specific epidemiologic issues.
Research in the C. John Sperati Lab focuses on hypertension and kidney diseases. Topics of recent studies include novel treatments for these conditions, secondary hypertension and the genetic epidemiology of chronic kidney disease. Within the area of hypertension, we are particularly interested fibromuscular dysplasia, hyperaldosteronism, atherosclerotic renal arterial disease and genetic hypertensive syndromes.
Research in the Caleb Alexander Lab examines prescription drug use. This includes studies of population-based patterns and determinants of pharmaceutical use, clinical decision-making about prescription drugs, and the effect of changes in regulatory and payment policies on pharmaceutical utilization. We have special expertise in conducting survey-based studies and analyzing secondary data sources, including administrative claims, the Medical Expenditure Panel Survey and the National Ambulatory Medical Care Survey.
Dr. Clare Rock is an assistant Professor of Medicine, Division of Infectious Diseases at the Johns Hopkins University School of Medicine, Associate hospital Epidemiologist at the Johns Hopkins Hospital, and Faculty Member at Armstrong Institute for Patient Safety and Quality. Her research interest focuses the prevention of pathogen transmission in the hospital environment. This includes novel strategies of improving patient room cleaning and disinfection, including human factors engineering approaches, and conducting robust clinical trials to examine effectiveness of "no touch" novel technologies such as UV-C light. She has particular interest in carbapenem-resistant Enterobacteriaceae transmission in the hospital environment, including outbreak management, and transmission and epidemiology of Clostridium difficile. Her other area of interest is diagnostic stewardship, and the behavioral, cultural and human factors aspects of implementation of initiatives to enhance appropriate use of ...diagnostic tests. She leads a national initiative, as part of the High Value Practice Academic Alliance, examining strategies for appropriate testing for Clostridium difficile. This is a wider implementation of work that Dr. Rock conducted with The Johns Hopkins Health System facilities.
Dr. Rock has multiple sources of grant funding including from the Agency of Healthcare Research and Quality, Centers for Disease Control and Prevention, and industry. Dr. Rock is Vice Chair of the Society for Healthcare Epidemiology of America Research Network, and serves on the SHEA research committee. Dr. Rock earned her M.B.B.Ch. at the University College Dublin School of Medicine, National University of Ireland, and her MS masters of clinical science of research at the University of Maryland, where she received the MS scholar award for epidemiology. view less
Research in the Cullman Chemoprotection Center focuses on developing nutritional strategies for chronic disease prevention in humans. Our work draws from natural product chemistry, enzymology, nutritional epidemiology and clinical research. A number of our studies look at the glucosinolates and isothiocyanates found in cruciferous vegetables and in Moringa oleifera, also known as the “drumstick tree.” Our team has found that broccoli sprouts are a rich source of the enzyme inducers that detoxify carcinogens and that two of the inducers — sulforaphane in broccoli and isothiocyanate in Moringa oleifera — act as strong antibiotics against Helicobacter pylori, which can cause peptic ulcer disease and stomach cancer.
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