Research in the Kendall Moseley Lab is focused on the interplay between type 2 diabetes, aging ...and osteoporosis. We also study the function of bone stem cells in the regulation of bone remodeling. view more

Research in the Mark Sulkowski Lab focuses on hepatitis B and hepatitis C. We've conducted clin...ical research related to the management of viral hepatitis, including novel agents. Other studies focus on adult patients at the Johns Hopkins site of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Hepatitis B Clinical Research Network as well as the National Institute of Allergy and Infectious Diseases Adult AIDS Clinical Trials Group. view more

The Wolfgang Laboratory is interested in understanding the metabolic properties of neurons and ...glia at a mechanistic level in situ. Some of the most interesting, enigmatic and understudied cells in metabolic biochemistry are those of the nervous system. Defects in these pathways can lead to devastating neurological disease. Conversely, altering the metabolic properties of the nervous system can have surprisingly beneficial effects on the progression of some diseases. However, the mechanisms of these interactions are largely unknown.

We use biochemical and molecular genetic techniques to study the molecular mechanisms that the nervous system uses to sense and respond to metabolic cues. We seek to understand the neurometabolic regulation of behavior and physiology in obesity, diabetes and neurological disease.

Current areas of study include deconstructing neurometabolic pathways to understand the biochemistry of the nervous system and how these metabolic pathways impact animal behavior and physiology, metabolic heterogeneity and the evolution of metabolic adaptation. view more

Research in the Mihail Zilbermint Lab focuses on diabetes, adrenal disease and thyroid disease.... Recent areas of focus include pseudohypoaldosteronism type 1 related to novel variants of SCNN1B gene, genetic variance in the ARMC5 gene in primary macronodular adrenocortical hyperplasia and hyperaldosteronism due to de novo KCNJ5 mutation. view more

The Nestoras Mathioudakis Lab focuses on improving patient safety and quality for hospitalized ...diabetes patients. Our interests include inpatient glucose management, type 2 diabetes mellitus and diabetic foot ulcers. view more

The Nisa Maruthur Lab studies primary care; individualized medicine for the prevention and trea...tment of type 2 diabetes and obesity; pharmacogenomics of type 2 diabetes; and comparative effectiveness. view more

Hypertension in children is a major cause of disease, including early onset heart disease. Up t...o 25% of children who are overweight or obese have hypertension (high blood pressure), and children with obesity are at greater risk for having other cardiovascular disease risk factors such as high cholesterol and diabetes. The ReNEW Clinic at The Johns Hopkins University provides an innovative multidisciplinary approach to the evaluation and treatment of obesity-related hypertension to help prevent and treat cardiovascular disease. This clinic is designed for children with elevated blood pressure (prehypertension and hypertension) and a BMI at or above the 85th percentile. Many children in this clinic are enrolled in a longitudinal registry to help researchers learn how to better care for children with multiple risk factors for heart disease.

Read more about the ReNEW clinic: Childhood Obesity: A Focus on Hypertension