Research Lab Results for diabetes
Adrian Dobs LabPrincipal Investigator:
Adrian Dobs, M.D., M.H.S.
Researchers in the Adrian Dobs Lab study topics that include gonadal dysfunction, hyperlipidemi...a, diabetes mellitus, and the relationship between sex hormones and heart disease. We currently are investigating male gonadal function—with particular interest in new forms of male hormone replacement therapy—and hormonal changes related to aging. view moreResearch Areas: diabetes mellitus, hormones, hyperlipidemia, male gonadal function, cardiovascular diseases, endocrinology
Aniket Sidhaye LabLab WebsitePrincipal Investigator:
Aniket Sidhaye, M.D.
Dr. Sidhaye is interested in improving the care of persons with cystic fibrosis, type 1 diabete...s mellitus and hospitalized person with diabetes. research topics include bone health of persons with CF undergoing lung transplant, CF-related diabetes mellitus, Care of persons with type 1 diabetes mellitus transitioning from pediatrics to adult specialty clinics, Management of hospitalized persons with diabetes. view moreResearch Areas: biochemistry, obesity, hormones, diabetes, transitional care, endocrinology, thyroid
Edgar Miller LabPrincipal Investigator:
Edgar Miller, M.D., Ph.D.
Research in the Edgar Miller Lab focuses on nutrition, hypertension and kidney disease. Current... projects include a National Heart, Lung, and Blood Institute study on dietary carbohydrate and glycemic index effects on markers of oxidative stress, inflammation and kidney function; and a National Institute of Diabetes and Digestive and Kidney Diseases randomized controlled trial that examines the effects of omega-3 fatty acid supplementation on urine protein excretion in diabetic kidney disease. view moreResearch Areas: nutrition, kidney diseases, diabetes, inflammation
Elizabeth Selvin LabPrincipal Investigator:
Elizabeth Selvin, Ph.D., M.P.H.
The Elizabeth Selvin Lab examines the intersection of epidemiology, clinical policy and public ...health policy. One of our key goals is to use the findings of epidemiologic research to inform the screening, diagnosis and treatment of diabetes, cardiovascular disease and kidney disease. Much of our work looks at biomarkers and diagnostics related to diabetes and diabetes complications. Our findings — linking hemoglobin A1c (HbA1c) to diabetic complications and identifying the role of A1c in diabetes diagnosis — have influenced clinical practice guidelines. view moreResearch Areas: epidemiology, biomarkers, kidney diseases, obesity, diabetes, health care policy, cardiovascular diseases
Fu LabLab WebsitePrincipal Investigator:
Dax Fu, Ph.D.
The Fu Lab is a basic research lab that studies zinc transport, with a particular focus on whic...h step in the zinc transport process may be modulated and how. Dr. Fu's lab uses parallel cell biology and proteomic approaches to understand how these physiochemical principles are applied to mammalian zinc transporters and integrated to the physiology of pancreatic beta cells. This research has implications for understanding how zinc transport is related to diabetes and insulin intake. view moreResearch Areas: cell biology, proteomics, zinc, pancreatic cells, diabetes
Hsin-Chieh Yeh LabLab WebsitePrincipal Investigator:
Jessica Yeh, Ph.D.
Work in the Hsin-Chieh Yeh Lab focuses on clinical trials and cohort studies of diabetes, obesi...ty and behavioral intervention, cancer and hypertension. Recent investigations have focused on novel risk factors and complications related to obesity and type 2 diabetes, particularly lung function, smoking and cancer. We recently co-led a randomized clinical trial of tailored dietary advice for consumption of dietary supplements to lower blood pressure and improve cardiovascular disease risk factors in hypertensive urban African Americans. view moreResearch Areas: epidemiology, African Americans, cancer, obesity, hypertension, diabetes, behavioral medicine
J. Hunter Young LabPrincipal Investigator:
Jeffery Young, M.D., M.H.S.
Research in the J. Hunter Young Lab focuses on the genetic epidemiology and physiology of cardi...ovascular disease and its risk factors, especially hypertension, diabetes and obesity. Current activities include an observational study of hypertension among African Americans; a genetic epidemiology study of worldwide cardiovascular disease susceptibility patterns; and several population-based observational studies of cardiovascular and renal disease. A recent focus group study found that changes in housing and city policies might lead to improved environmental health conditions for public housing residents. view moreResearch Areas: epidemiology, kidney diseases, obesity, hypertension, diabetes, genomics, physiology, cardiovascular diseases
Jeanne Clark Lab: GIM ResearchLab WebsitePrincipal Investigator:
Jeanne Clark, M.D., M.P.H.
Research in the Jeanne Clark Lab covers a wide range of fields, employing various research tech...niques, methods and procedures to generate and disseminate the knowledge required to prevent disease and its consequences. Our most recent research program, Look AHEAD, focuses on the health of overweight volunteers with type 2 diabetes. We are examining the long-term effects of an intensive lifestyle intervention program designed to achieve and maintain weight loss by decreased caloric intake and increased physical activity. view moreResearch Areas: epidemiology, diabetes mellitus, obesity, diabetes, Nonalcoholic Fatty Liver Disease, liver diseases
Jodi Segal LabPrincipal Investigator:
Jodi Segal, M.D., M.P.H.
Research in the Jodi Segal Lab focuses on developing methodologies to use observational data to... understand the use of new drugs, particularly drugs for treating diabetes, blood disorders and osteoporosis. We apply advanced methods for evidence-based review and meta-analysis, and—in collaboration with Johns Hopkins biostatisticians—we have developed new methodologies for observational research (using propensity scores to adjust for covariates that change over time) and methods to account for competing risks and heterogeneity of treatment effects in analyses. view moreResearch Areas: blood disorders, osteoporosis, diabetes, drugs, evidence-based medicine
Katherine Wilson LabPrincipal Investigator:
Katherine Wilson, Ph.D.
Research in the Wilson Lab focuses on three components of nuclear lamina structure: lamins, LEM...-domain proteins (emerin), and BAF.Research Areas: cell biology, Emery-Dreifuss muscular dystrophy (EDMD), accelerated aging, chromatin, diabetes, genomics, emerin, nuclear lamina, lipodystrophy, cardiomyopathy
These three proteins all bind each other directly, and are collectively required to organize and regulate chromatin, efficiently segregate chromosomes and rebuild nuclear structure after mitosis. Mutations in one or more of these proteins cause a variety of diseases including Emery-Dreifuss muscular dystrophy (EDMD), cardiomyopathy, lipodystrophy and diabetes, and accelerated aging.
We are examining emerin's role in mechanotransduction, how emerin and lamin A are regulated, and whether misregulation contributes to disease.