Research in the David Hager Lab focuses on critical care medicine. Recent studies includes an a...nalysis of advances in the management of the acute respiratory distress syndrome (ARDS) and the development of a targeted real-time early warning score predicting septic shock. Other interests include ventilator-induced lung injury and high-frequency ventilation. view more

Work in the Donald Shaffner Lab investigates several topics within critical care medicine. Our ...team conducts research on the mechanisms involved in neurologic injury from global ischemia as a result of cardiac arrest and resuscitation. We also study neurologic outcomes of pediatric patients who experience cardiac arrest. view more

Work in the Enid Neptune Lab focuses on topics within the fields of pulmonary and critical care... medicine. Our research centers primarily on therapeutic strategies for Marfan syndrome and hepatocyte growth factor signaling in airspace homeostasis. We also conduct research on chronic obstructive pulmonary disease (COPD), with a focus on its mechanisms and potential methods for preventing its progression. Our research within critical care has most recently involved investigating superoxide dismutase 3 dysregulation in neonatal lung injuries. view more

Research in the Ivor Berkowitz Lab targets pediatric critical care medicine. We are particularl...y interested in the pathophysiology behind the cerebrovascular dysfunction that occurs in bacterial meningitis as well as the anesthetic and perioperative complications of patients with dwarfing syndromes. view more

Research in the Larissa Shimoda Lab focuses on several important topics within pulmonary and cr...itical care medicine. We primarily study pulmonary arterial responses to chronic hypoxia as well as hypoxic pulmonary vasoconstriction and oxidant-mediated lung injury. Our recent research has included investigating the effects of chronic hypoxia on pulmonary circulation and the ways in which hypoxia-inducible factors impact pulmonary vascular responses to hypoxia. We have also studied vascular remodeling in patients with pulmonary hypertension. view more

Research in the Mary Beth Brady Lab focuses primarily on topics within the fields of anesthesio...logy, imaging and cardiology. Our work has explored transesophageal echocardiography simulation, echocardiography, cardiac and vascular-thoracic anesthesiology, and other areas within critical care medicine. A recent study involved obtaining 3-D images of the heart, which were then used to build computer programs to help cardiac surgeons improve their treatment of heart defects. view more

Work in the Pedro Alejandro Mendez-Tellez Lab focuses on critical care medicine and acute lung ...injury. Recent studies include evaluating demographic and clinical factors associated with self-reported dysphagia after oral endotracheal intubation and mechanical ventilation in patients with acute lung injury. We've also analyzed orticosteroids and their relationship with delirium in critically ill patients. view more