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Displaying 1 to 9 of 9 results for chronic kidney disease

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  • Chirag Parikh Lab

    Dr. Parikh's research focuses on the translation and validation of novel biomarkers for the diagnosis and prognosis of acute kidney injury. Progress in kidney diseases has been hamstrung by significant heterogeneity within the current disease definitions, which are largely based on serum creatinine. Dr. Parikh's research has addressed this critical challenge by developing biomarkers of renal tubular injury, repair, and inflammation to dissect this heterogeneity. He has assembled multicenter longitudinal prospective cohorts for translational research studies across several clinical settings of acute kidney injury and chronic kidney disease for the efficient translation of novel biomarkers.



    His research is dedicated to the process of applying discoveries generated in the laboratory and in preclinical experiments, the development of clinical studies, and the design of clinical trials. Dr. Parikh's studies have refined the clinical definition in perioperative acute kidney in...jury and hepatorenal syndrome, developed strategies to reduce kidney discard in deceased donor transplantation, and advanced regulatory approvals of kidney injury biomarkers. He has also developed biomarkers to identify rapid progressors of early diabetic kidney disease before derangements in serum creatinine. Dr. Parikh's research goal is to translate our understanding of pathophysiological mechanisms into clinical practice and improve the outcomes in patients with kidney disease.



    Dr. Parikh has also been the recipient of numerous honors, including the 2017 Young Investigator Award from the American Society of Nephrology.
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    Research Areas: acute kidney injury, biomarkers, Kidney Transplantation, chronic kidney disease

    Lab Website

    Principal Investigator

    Chirag Parikh, M.B.B.S., Ph.D.

    Department

    Medicine

  • Deidra Crews Lab

    Dr. Crews’ team focuses on health disparities in chronic kidney disease. We have studied how social determinants of health, such as poverty and healthful food access, affect disparities in kidney disease outcomes. Our research on end-stage renal disease includes studies of the best timing and environment to initiate dialysis among vulnerable populations.

    Research Areas: poverty, chronic kidney disease, health disparities

    Principal Investigator

    Deidra Crews, M.D.

    Department

    Medicine

  • Kristin Riekert Lab

    Work in the Kristin Riekert Lab focuses on methods for improving health care quality and delivery, particularly among underserved and disadvantaged populations. Our research covers a range of important topics, including health beliefs, treatment adherence, doctor-patient communication, self-management interventions, mobile health initiatives, health disparities and patient-reported outcome methodology. We also work with the National Institutes of Health on multiple intervention trials focused on improving adherence and health outcomes in asthma, chronic kidney disease, cystic fibrosis (CF), sickle cell disease and secondhand smoke reduction.

    Research Areas: health care quality, treatment adherence, cystic fibrosis, patient-provider relationships, chronic illnesses, health disparities

    Principal Investigator

    Kristin Riekert, Ph.D.

    Department

    Medicine

  • Morgan Grams Lab

    Dr. Morgan Grams and her colleagues are involved in a wide range of clinical research projects applying quantitative methods to multidimensional data to develop actionable clinical indicators. Along with Dr. Josef Coresh, Dr. Grams leads the Chronic Kidney Disease (CKD) Prognosis Consortium, a global consortium of over 200 investigators and >11 million participants (https://ckdpc.org). They have developed and validated several risk calculators that are now widely used in clinical practice (https://ckdpcrisk.org). She holds a joint appointment in the Bloomberg School of Public Health, where she is a member of the Center of Drug Safety and Effectiveness. Her research in pharmacoepidemiology leverages electronic health records from multiple countries to evaluate the risks and benefits of commonly used medications across the spectrum of kidney function. Together with her team, Dr. Grams also focuses on identifying targetab...le pathways or biomarkers that underlie the development of chronic kidney disease using multi-omic approaches.



    Dr. Grams received the 2019 Frederick Brancati Mentoring Award. Currently, four of her mentees are supported by NIH K awards. More of their research can be found here: http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/40940579/?sort=date&direction=descending
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    Research Areas: organ donors, hyperglycemia, biomarkers, chronic kidney disease, health disparities

    Lab Website

    Principal Investigator

    Morgan Grams, M.D., M.H.S., Ph.D.

    Department

    Medicine

  • Rakhi Naik Lab

    The Rakhi Naik Lab studies sickle cell disease. We focus on complications related to the disease, including chronic kidney disease and venous thromboembolism. By defining the risks and factors for diseases related to the sickle cell trait, we hope to improve genetic counseling and screening and treatment recommendations. Other research in the lab examines the epidemiology and unique mechanisms of thrombosis in patients with hemoglobin disorders. Specifically, we are trying to identify mechanisms of hypercoagulability and develop treatments for patients with hemoglobinopathies.

    Research Areas: epidemiology, sickle cell diseases, kidney diseases, venous thromboembolism, hemoglobin disorders, genetic counseling

    Principal Investigator

    Rakhi Naik, M.D., M.H.S.

    Department

    Medicine

  • Raquel Greer Lab

    Work in the Raquel Greer Lab focuses primarily on health disparities in chronic kidney disease. Our most recent research explored the challenges perceived by primary care providers in educating patients about chronic kidney disease as well as physicians’ views on barriers to adequate preparation of patients for renal replacement therapy. We also are interested in examining how clinical-patient communication can impact quality of care in the primary care setting.

    Research Areas: primary care, kidney diseases, patient-provider relationships

    Principal Investigator

    Raquel Greer, M.D., M.H.S.

    Department

    Medicine

  • Sharon Turban Lab

    Research in the Sharon Turban Lab focuses on the effects of sodium and potassium on blood pressure and on kidney function. We lead the Chronic Kidney Disease-Potassium (CKD-K) clinical trial, funded by American Heart Association, which examines the benefits and safety of two levels of potassium intake in patients with kidney disease. Other research includes the Chronic Renal Insufficiency Cohort (CRIC) study, which aims to improve the understanding of chronic kidney disease and related cardiovascular illness.

    Research Areas: sodium, kidney diseases, potassium, chronic kidney disease, blood pressure

    Principal Investigator

    Sharon Turban, M.D.

    Department

    Medicine

  • Stephen Sozio Lab

    Dr. Sozio’s research focuses on 1) Clinical research related to chronic kidney disease and end stage renal disease, and 2) Educational research in undergraduate and graduate medical education.



    The Sozio lab pursues work related to stroke, cognitive impairment, manifestations of kidney disease, and systematic reviews on clinical topics, and collaborates on multiple projects with other key investigators. In particular, Dr. Sozio has been an active investigator in the Choices for Healthy Outcomes in Caring for ESRD (CHOICE) Study, Predictors of Arrhythmic and Cardiovascular Risk in End Stage Renal Disease (PACE) Study, Chronic Renal Insufficiency Cohort (CRIC) Study, and work funded through the Agency for Healthcare Research and Quality (AHRQ) and Johns Hopkins Evidence-Based Practice Center. In addition, the Sozio lab performs studies at the UME and GME levels, investing in understanding learners’ mentorship, research, and transitional experiences.

    Research Areas: end stage renal disease (ESRD), epidemiology, kidney diseases, stroke

    Principal Investigator

    Stephen Sozio, M.D.

    Department

    Medicine

  • Steven Menez Lab

    Dr. Menez and his laboratory are interested in clinical and translational acute kidney injury (AKI) research, specifically with a focus on the transition between AKI and chronic kidney disease (CKD). Dr. Menez has investigated novel approaches to evaluate AKI using biomarkers of kidney injury, inflammation, and repair in the multi-center TRIBE-AKI and ASSESS-AKI Studies. Dr. Menez collaborates nationwide through the NIDDK-sponsored Kidney Precision Medicine Project, with a goal to improve the global understanding of kidney disease subgroups and identify new pathways and targets for novel therapies.



    Since the start of the COVID-19 pandemic, he has additionally investigated the impact of COVID19 on kidney health, including short-term outcomes including need for dialysis or in-hospital mortality, as well as longer-term outcomes post-hospital discharge.

    Research Areas: acute kidney injury, chronic kidney disease

    Principal Investigator

    Steven Menez, M.D., M.H.S.

    Department

    Medicine

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