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Research Lab Results for cancer stem cells

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  • Richard John Jones Lab

    Principal Investigator:
    Richard Jones, M.D.
    Medicine

    The Richard J. Jones Lab studies normal and cancerous stem cells in order to make clinical improvements in areas such as blood and marrow transplantation (BMT). We discovered one of the most common stem-cell markers, Aldefluor, which identifies cells based on their expression of aldehyde dehydrogenase 1 (ALDH1), and have used this marker to detect and characterize normal stem cells and cancer stem cells from many hematologic malignancies. We also developed post-transplant cyclophosphamide and effective related haploidentical BMT.

    Research Areas: enzymes, stem cells, blood and marrow transplantation, leukemia, cancer
  • Zambidis Laboratory

    Principal Investigator:
    Elias Zambidis, M.D., Ph.D.
    Oncology

    The Zambidis Labratory studies the formation of pluripotent stem cells and the subsequent hematopoietic, endothelial and cardiac differentiation, as well as the potential therapeutic uses of pluripotent stem cell-derived cells.

    Research Areas: stem cells, vasculogenesis, cardiogenesis, hematopoiesis, cancer stem cells, pluripotency
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