The Zhu lab is focused on characterizing the activities of large collection of proteins, buildi...ng signaling networks for better understanding the mechanisms of biological processes, and identifying biomarkers in human diseases and cancers.

More specifically, our group is interested in analyzing protein posttranslational modifications, and identifying important components involved in transcription networks and host-pathogen interactions on the proteomics level, and biomarkers in human IBD diseases. view more

The Zsuzsanna McMahan Lab conducts translational research that seeks to identify the novel anti...gens in scleroderma and to define the target tissue in this disease. We are conducting two active clinical research trials, including one that studies skin biopsy specimens as biomarkers of scleroderma and the response to mycophenolate mofetil (MMF or Cellcept). The other study is a gastrointestinal involvement registry that follows patients who are experiencing GERD, small bowel bacterial overgrowth, constipation, fecal incontinence and gastroparesis to see if there is improvement in symptoms after a change in treatment is implemented. view more