Research Lab Results for bacterial pathogens
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Advanced Optics Lab
Lab WebsiteThe Advanced Optics Lab uses innovative optical tools, including laser-based nanotechnologies, ...to understand cell motility and the regulation of cell shape. We pioneered laser-based nanotechnologies, including optical tweezers, nanotracking, and laser-tracking microrheology. Applications range from physics, pharmaceutical delivery by phagocytosis (cell and tissue engineering), bacterial pathogens important in human disease and cell division.
Research Areas: optics, microscopy, physics, cellular biology, imaging, nanotechnology, drugs, tissue engineering
Other projects in the lab are related to microscopy, specifically combining fluorescence and electron microscopy to view images of the subcellular structure around proteins. view more -
Caren L. Freel Meyers Laboratory
Lab WebsiteThe long-term goal of the Caren L. Freel Meyers Laboratory is to develop novel approaches to ki...ll human pathogens, including bacterial pathogens and malaria parasites, with the ultimate objective of developing potential therapeutic agents.
Research Areas: bacterial pathogens, biochemistry, enzymes, infectious disease, protein expression, synthetic chemistry, isoprenoid biosynthesis, malaria, pharmacology, chemistry, molecular biology
Toward this goal, we are pursuing studies of bacterial isoprenoid biosynthetic enzymes comprising the methylerythritol phosphate (MEP) pathway essential in many human pathogens. Studies focus on understanding mechanism and regulation in the pathway toward the development of selective inhibitors of isoprenoid biosynthesis. Our strategies for creating new anti-infective agents involve interdisciplinary research in the continuum of organic, biological and medicinal chemistry. Molecular biology, protein expression and biochemistry, and synthetic chemistry are key tools for our research.
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