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Research in the John McCloskey Lab focuses on quality improvements in the operating room and pediatric intensive care unit (PICU). Our work aims to improve the throughput of adolescents undergoing spinal fusions in order to better define interventions to ameliorate anesthesia emergence delirium and to improve protocols for sedation. One of our projects established an early oral feeding program for critically ill patients. Our goal is to enhance the delivery and quality of children’s health care while making it safer and more affordable.
The Michelle Eakin Lab conducts research on behavioral science and adherence and asthma outcomes in inner-city children. Our studies into behavioral science have included exploring the impact of medication adherence on lung health outcomes in patients with cystic fibrosis, disparities in anti-hypertensive medication adherence in adolescents and other key topics. We also investigate methods for improving asthma care and treatment as well as health disparities among various ethnicities, particularly in pediatric patients.
Research in the Richard Chaisson Lab primarily examines tuberculosis and HIV infection, with specific focus on global epidemiology, clinical trials, diagnostics and public health interventions. Our recent research has involved evaluating a molecular diagnostic test for tuberculosis in HIV patients; observing TB responses during treatment of pulmonary tuberculosis; and examining antiretroviral therapy adherence, virologic and immunologic outcomes in adolescents compared with adults in Southern Africa.
Research in the Sara Mixter Lab focuses on primary care medical education, particularly quality improvement, high-value care and care transitions for adolescents with developmental disabilities and other special health care needs.
The Virginia Weaver Lab uses molecular epidemiology tools to evaluate chemically exposed populations. We explore the validation of exposure and early biological effect markers for research and medical surveillance. Our primary research area is the effects of occupational and environmental toxicants on the kidney. We are currently investigating how metals affect kidney function, examining in particular clinical measures and early biological effect markers, including urinary N-acetyl-beta-D-glucosaminidase. Our studies have involved populations of lead workers in South Korea and environmentally exposed adolescents in Mexico.
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