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Research Lab Results for Sjogren's syndrome

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  • Alan Baer Lab

    Principal Investigator:
    Alan Baer, M.D.
    Medicine

    Research in the Alan Baer Lab focuses on Sjogren's syndrome. Previously, we conducted the Sjogr...en's International Registry (SICCA), enrolling 300 patients and creating a valuable source of clinical data and biospecimens for research we're conducting with colleagues at Johns Hopkins and the University of California-San Francisco. Currently, we're conducting a longitudinal observational study of patients with Sjogren's syndrome. We're also collaborating with Dr. Ben Larman in the Department of Pathology, using phage immuno-precipation sequencing to work on a characterization of the complete autoantibody repertoire in Sjogren's syndrome patients. view more

    Research Areas: autoantibodies, Sjogren's syndrome, autoimmune rheumatic diseases, observational data
  • Livia Casciola-Rosen Lab

    Principal Investigator:
    Livia Casciola-Rosen, Ph.D.
    Medicine

    Work in the Livia Casciola-Rosen Lab explores the shared mechanisms present in autoimmune rheum...atic diseases, specifically scleroderma, Sjogren's syndrome and myositis. We use disease-specific autoantibodies to identify the factors that cause the autoimmune response in such diseases. Our current research involves identifying the antigen targets of autoimmune diseases, investigating the autoantigens targeted in cancers associated with rheumatic diseases and finding unique clinical biomarkers, such as the anti-HMGCR antibody specificity. view more

    Research Areas: autoantibodies, myositis, rheumatology, Sjogren's syndrome, scleroderma, autoimmune rheumatic diseases
  • Sonye Danoff Lab

    Principal Investigator:
    Sonye Danoff, M.D., Ph.D.
    Medicine

    Research in the Sonye Danoff Lab includes both basic and translational studies of lung fibrosis.... We have explored topics such as the role of support measures and palliative care, pulmonary manifestations of Sjogren's syndrome, idiopathic inflammatory myopathies and the treatment of cough in idiopathic pulmonary fibrosis. Our research has also involved investigating the lung as a potential target for the immune reaction in myositis. view more

    Research Areas: myositis, interstitial lung diseases, Sjogren's syndrome, lung disease, pulmonary fibrosis, autoimmune diseases
  • The Cihakova Lab

    Lab Website
    Principal Investigator:
    Daniela Cihakova, M.D., Ph.D.
    Pathology

    The Cihakova research laboratory is an immunology laboratory dedicated to the investigation of ...autoimmune diseases. Our most active research is focused on myocarditis and dilated cardiomyopathy. We expanded our interest in inflammatory heart diseases to include the study of immune mechanisms driving pericarditis and myocardial infarction. In addition, we are interested in the pathogenesis of a broad range of autoimmune diseases such as, Sjogren's syndrome, congenital complete heart block, and APECED (autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy). Through several collaborative projects we also investigate rheumatoid arthritis and the immune components of schizophrenia. view more

    Research Areas: schizophrenia, autoimmune diseases, myocardial infarction, cardiomyopathy
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