The Michael Edidin Lab studies membrane dynamics and organization in cells from lymphocytes to epithelial cells using biochemistry, biophysics (especially fluorescence methods), cell biology, biochemistry and immunology. We are interested in transplantation immunology, particularly in the cell biology of class I MHC molecules, and are working to understand the relationship between plasma membrane biophysics and antigen presentation by MHC molecules. We are currently studying the clustering of T cell receptors for the antigen TCR.