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Displaying 1 to 3 of 3 results for Crohn’s disease

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  • Brindusa Truta Lab

    The Brindusa Truta Lab studies inflammatory bowel diseases, specifically Crohn’s disease and ulcerative colitis. Recent studies defined factors associated with the development of Crohn's disease after ileal pouch anal anastomosis; determined the value of histology in identifying Lynch syndrome in early-onset of colorectal cancer patients; and compared the phenotype and genotype in adenomatous polyposis patients with and without a family history.

    Research Areas: inflammatory bowel disease, Crohn’s disease, ulcerative colitis

    Principal Investigator

    Brindusa Truta, M.A.S., M.D.

    Department

    Medicine

  • IBD and Autoimmune Liver Diseases Laboratory

    Investigators in the IBD and Autoimmune Liver Diseases Laboratory conduct basic and translational research in inflammatory bowel disease (IBD) and autoimmune liver diseases. One area of focus is discovering and developing biomarkers for diagnosing and prognosticating IBD and other autoimmune liver diseases (AILDs). We also are exploring the molecular pathogenesis of—and developing novel therapies for—IBD. In addition, we are working to understand the molecular reason why many IBD patients fail to respond to mainstay drug therapies—and to develop diagnostic assays that can predict non-responders before starting them on those therapies. These biomarker studies have led to our application for four U.S. and international patents.

    Research Areas: inflammatory bowel disease, Crohn’s disease, gastrointestinal system, colitis, autoimmune diseases, pathogenesis, celiac disease, liver diseases

    Lab Website

    Principal Investigator

    Xu Li, Ph.D.

    Department

    Medicine

  • Susan Hutfless Lab

    The Susan Hutfless Lab uses administrative data to investigate epidemiologic questions about the causes of and treatments for chronic diseases, with a focus on gastrointestinal disorders. Our team has provided epidemiologic expertise to help design and analyze large-dataset studies of cervical cancer, colorectal cancer and mortality related to inflammatory bowel disease (IBD). We also have conducted research on infection-related triggers of Crohn’s disease in susceptible military personnel as well as prenatal and childhood predictors of pediatric-onset IBD.

    Research Areas: inflammatory bowel disease, Crohn’s disease, epidemiology, data analysis, maternal health, chronic disease, gastrointestinal

    Principal Investigator

    Susan Hutfless, Ph.D., S.M.

    Department

    Medicine

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