Research Lab Results for Angelman syndrome
Seth Margolis LaboratoryPrincipal Investigator:
Seth Margolis, Ph.D.
The Seth Margolis Laboratory studies the signaling pathways that regulate synapse formation dur...ing normal brain development to try to understand how, when these pathways go awry, human cognitive disorders develop.Research Areas: cognition, Angelman syndrome, human development, cellular signaling, synapse formation
We use Ephexin5 to study the molecular pathways that regulate restriction of excitatory synapse formation and their relevance to the pathophysiology of Angelman syndrome. view more