Find a Research Lab

Enter a research interest, principal investigator or keyword

Displaying 1 to 4 of 4 results for Air pollution

Show: 10 · 20 · 50

  1. 1
  • Meredith McCormack Lab

    Research in the Meredith McCormack Lab deals primarily with pulmonary diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and the role of environmental exposures in lung diseases. We have researched the factors that contribute to inner-city asthma, with a focus on how particulate matter air pollution impacts pulmonary function. We are also part of the LIBERATE clinical study, which is focused on patients who experience difficulty breathing and have been diagnosed with severe emphysema. We also have a longstanding interest in the effects of race/ethnicity, poverty and urbanization on nutrition and food allergies.

    Research Areas: emphysema, environmental exposure, asthma, lung disease, COPD, health disparities

    Principal Investigator

    Meredith McCormack, M.D., M.H.S.

    Department

    Medicine

  • Patrick Breysse Lab

    Research in the Patrick Breysse Lab seeks to better understand the biological, chemical and physical factors that can impact a patient’s health. Our team is currently studying the effects of indoor and outdoor air pollution on childhood asthma, respiratory tract infections, chronic obstructive pulmonary disease (COPD) and other respiratory conditions. We also conduct research on secondhand smoke exposure around the world and have participated in a range of health and exposure studies in Peru, Nepal, Mongolia, Columbia and India.

    Research Areas: epidemiology, pollution, asthma, COPD, pediatrics

    Principal Investigator

    Patrick Breysse, M.H.S., Ph.D.

    Department

    Medicine

  • Shyam Sundar Biswal Lab

    xResearch in the Shyam Biswal Lab focuses on therapeutic resistance of cancer due to a gain-of-function mutation in transcription factor Nrf2. Using patient-derived xenografts in humanized immunocompetent mice and GEM models, we aim to understand the mechanisms of oncogenic cooperation and metabolic adaptation in cancer cells. We’re also investigating the systemic and pulmonary effects of air pollution as well as the health effects of recent tobacco products, such as electronic cigarettes and water pipes.

    Research Areas: Nrf2, tobacco use, genetics, cancer, pulmonary medicine, environment, lung cancer

    Principal Investigator

    Shyam Biswal, Ph.D.

    Department

    Medicine

  • The Ramanathan Lab

    Chronic rhinosinusitis (CRS) is a leading cause of morbidity globally and is the single most common self-reported chronic health condition and accounts for billions of dollars in health care costs and lost work days annually. Exposure to air pollutants is thought to be a critical modifier of CRS susceptibility. Despite marked reductions in air pollution levels in the United States, the fine particulate component of air pollution (PM2.5) and ultrafine pollutants secondary to traffic continue to remain a recalcitrant issue globally and in the United States. The Ramanathan Lab focuses on studying the role of air pollution (PM2.5) in CRS. In collaboration with scientists at the Bloomberg School of Public Health, we have utilized a state of the art air pollution exposure system to develop a novel mouse model of air pollution induced rhinosinusitis that mimics many of the features of CRS in humans. Our lab uses transgenic mouse models and novel immunologic/genomic techniques to study the mec...hanisms by which PM2.5 causes eosinophilic inflammation and sinonasal epithelial barrier dysfunction. We are also interested in the role of the antioxidant transcription factor, Nrf2, which has shown to stabilize the epithelial barrier and reduce eosinophilia in PM induced rhinosinusitis as a potential therapeutic target. view more

    Research Areas: nasal polyps, Nrf2, sinonasal epithelial barrier function, particulate matter, chronic rhinosinusitis, epithelial damage, Air pollution

  1. 1