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Displaying 21 to 28 of 28 results for AIDS

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  • Neuroimmunopathology Lab

    The research activities of the Neuroimmunopathology Laboratory focus on studies of immunological and molecular mechanisms involved in the pathogenesis of neurological disorders. Our main areas of research include studies of neurological complications of HIV infection and AIDS, multiple sclerosis, transverse myelitis, autism and epilepsy. We seek to explore and identify immunopathological mechanisms associated with neurological disease that may be the target of potential therapeutic interventions. The laboratory collaborates with other researchers and laboratories at Johns Hopkins and other institutions in projects related with studies of the interaction between the immune and central nervous systems in pathological processes leading to neurological dysfunction.

    Research Areas: multiple sclerosis, autism, epilepsy, HIV, transverse myelitis

    Principal Investigator

    Carlos Pardo-Villamizar, M.D.

    Department

    Neurology
    Neurosurgery

  • Philip Smith Lab

    Work in the Philip Smith Lab explores several key topics within the field of sleep medicine. We investigate the role of obesity and neural control in sleep-disordered breathing as well as the impact of metabolic function on sleep apnea. We also research the ways in which HIV and its treatments impact a patient’s sleep. Our studies have included the effects of HIV and highly active antiretroviral therapy (HAART) on both sleep and daytime function as well as the relationship between systemic inflammation and sleep apnea in men with HIV.

    Research Areas: AIDS, sleep medicine, obesity, HIV, metabolic function, sleep apnea

    Principal Investigator

    Philip Smith, M.D.

    Department

    Medicine

  • Richard Chaisson Lab

    Research in the Richard Chaisson Lab primarily examines tuberculosis and HIV infection, with specific focus on global epidemiology, clinical trials, diagnostics and public health interventions. Our recent research has involved evaluating a molecular diagnostic test for tuberculosis in HIV patients; observing TB responses during treatment of pulmonary tuberculosis; and examining antiretroviral therapy adherence, virologic and immunologic outcomes in adolescents compared with adults in Southern Africa.

    Research Areas: global health, epidemiology, infectious disease, AIDS, HIV, tuberculosis

    Principal Investigator

    Richard Chaisson, M.D.

    Department

    Medicine

  • Richard Moore Lab

    Research interests in the Richard Moore Lab include clinical epidemiology, costs, cost-effectiveness and outcomes of HIV/AIDS. We recently examined whether the effect of delaying antiretroviral therapy initiation in HIV-positive adults is modified by age at entry into care.

    Research Areas: epidemiology, antiretroviral therapies, AIDS, HIV

    Principal Investigator

    Richard Moore, M.D.

    Department

    Medicine

  • Stuart C. Ray Lab

    Chronic viral hepatitis (due to HBV and HCV) is a major cause of liver disease worldwide, and an increasing cause of death in persons living with HIV/AIDS. Our laboratory studies are aimed at better defining the host-pathogen interactions in these infections, with particular focus on humoral and cellular immune responses, viral evasion, inflammation, fibrosis progression, and drug resistance. We are engaged in synthetic biology approaches to rational vaccine development and understanding the limits on the extraordinary genetic variability of HCV.

    Research Areas: immunology, Hepatitis, AIDS, HIV, hepatitis B, hepatitis C, liver diseases, synthetic biology

    Lab Website

    Principal Investigator

    Stuart Ray, M.D.

    Department

    Medicine

  • Thomas Quinn Lab

    Research in the Thomas Quinn Lab encompasses epidemiology, pathogenesis and clinical features of HIV/AIDS internationally, which includes the interaction between STDs and tropical diseases on the natural history and spread of HIV/AIDS in developing countries. Our recent research has examined the viral kinetics and transmission probabilities of HIV among discordant couples with the subsequent design and application of interventions, including therapy to prevent transmission of HIV. Molecular studies have mapped the molecular epidemic of HIV on a global basis, linking virologic changes to the spread of HIV and measuring the demographic impact of the epidemic.

    Research Areas: epidemiology, infectious disease, AIDS, HIV, sexually transmitted diseases, pathogenesis

    Principal Investigator

    Thomas Quinn, M.D.

    Department

    Medicine

  • Wu Lab

    Dr. Wu leads a multi-disciplinary team with collaborators from the Bloomberg School of Public Health, JHU Whiting School of Engineering, and JHU Krieger School of Arts and Sciences. She conducts ongoing investigations with the Multicenter AIDS Cohort Study and Women’s Inter-agency Health Study. Her lab’s goals are to develop, implement, and validate novel imaging-based metrics of cardiac structure and function to improve risk prediction and stratification at the individual patient-level.

    Research Focuses:

    Predictors of Sudden Cardiac Death by Magnetic Resonance Imaging
    Subclinical myocardial disease in people living with HIV
    Individualized risk prediction
    Cardiac structural and mechanical modeling

    Research Areas: AIDS, HIV, risk prediction, myocardial disease

    Principal Investigator

    Katherine Wu, M.D.

    Department

    Medicine

  • Yukari Manabe Lab

    Investigators in the Yukari Manabe Lab evaluate the accuracy of rapid, point-of-care diagnostics for HIV, tuberculosis and related infectious diseases in resource-limited settings particularly sub-Saharan Africa and examine the impact of diagnostic interventions on disease detection and patient outcomes. The team also conducts operational and translational research in tuberculosis and HIV co-infection.

    Research Areas: Africa, infectious disease, AIDS, HIV, point-of-care diagnostics, resource limitations, tuberculosis

    Principal Investigator

    Yuka Manabe, M.D.

    Department

    Medicine

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